Abstract: Butyrylcholinesterase inhibitors, their formulation, and their use primarily in the treatment of neurodegenerative diseases. These inhibitors generally are phosphates, phosphonates, phosphinates, and phosphoramidates. These inhibitors can be incorporated in pharmaceutical compositions and administered to a patient in therapeutically effective amounts to treat neurodegenerative diseases.
Abstract: A device for the removal of heavy metals and heavy metal complexes, such as thimerosal, from medications is provided wherein the device comprises a solid support having at least one substantially purified metallothionein protein associated therewith.
Abstract: Metal binding proteins, associated compositions and methods for their production and use are disclosed. The metal binding proteins included have amino acid sequences analogous to at least one metal binding protein, and conservative amino acid substitutions thereof from a brine shrimp (Artemia). Also provided are the associated nucleic acid sequences encoding metal binding proteins.
Type:
Application
Filed:
June 13, 2008
Publication date:
October 30, 2008
Applicant:
MGP BIOTECHNOLOGIES, LLC
Inventors:
Roger A. Acey, Michael Mustillo, Brenton G. Harpham
Abstract: Devices, such as solid supports having metal binding proteins, such as metallothionein proteins, bound thereto are disclosed for removing metals from substrates in need of having such metals removed therefrom. Specifically membranes having metallothionein proteins from the brine shrimp Artemia are disclosed for removing metals from liquid substrates. Associated methods for removing metals from substrates using metallothionein proteins are also disclosed.
Abstract: Metal binding proteins, associated compositions and methods for their production and use are disclosed. The metal binding proteins included have amino acid sequences analogous to at least one metal binding protein, and conservative amino acid substitutions thereof from a brine shrimp (Artemia). Also provided are the associated nucleic acid sequences encoding metal binding proteins.
Type:
Application
Filed:
August 23, 2006
Publication date:
May 24, 2007
Applicant:
MGP BIOTECHNOLOGIES, LLC
Inventors:
Roger Acey, Michael Mustillo, Brenton Harpham
Abstract: Metal binding proteins, associated compositions and methods for their production and use are disclosed. The metal binding proteins include have amino acid sequences analogous to at least one metal binding protein, and conservative amino acid substitutions thereof from a brine shrimp (Artemia). Also provided are the associated nucleic acid sequences encoding metal binding proteins.
Type:
Grant
Filed:
March 9, 2004
Date of Patent:
November 14, 2006
Assignee:
MGP Biotechnologies, LLC
Inventors:
Roger A. Acey, Michael Mustillo, Brenton Glen Harpham
Abstract: Devices, such as solid supports having metal binding proteins, such as metallothionein proteins, bound thereto are disclosed for removing metals from substrates in need of having such metals removed therefrom. Specifically membranes having metallothionein proteins from the brine shrimp Artemia are disclosed for removing metals from liquid substrates. Associated methods for removing metals from substrates using metallothionein proteins are also disclosed.
Abstract: Metal binding proteins, associated compositions and methods for their production and use are disclosed. The metal binding proteins include have amino acid sequences analogous to at least one metal binding protein, and conservative amino acid substitutions thereof from a brine shrimp (Artemia). Also provided are the associated nucleic acid sequences encoding metal binding proteins.
Type:
Application
Filed:
March 9, 2004
Publication date:
December 30, 2004
Applicant:
MGP Biotechnologies LLC
Inventors:
Roger A. Acey, Michael Mustillo, Brenton G. Harpham