Abstract: A device (10) having a blood oxygenator (12) and heat exchanger (14) of the outside perfusion type. The blood oxygenator (12) employs a tightly packed, crisscrossing bundle of gas permeable hollow fibers (50). The heat exchanger (14) employs a bundle of polyurethane, liquid impermeable hollow tubes (96). A center divider (16) facilitates two separate compartments (30, 40) and allows control over pack densities within each compartment while allowing blood to move in a planar manner throught out the device (10).

Abstract: A device having a blood oxygenator and heat exchanger of the outside perfusion type. The blood oxygenator employs a tightly packed, crisscrossing bundle of gas permeable hollow fibers. The heat exchanger employs a bundle of polyurethane, liquid impermeable hollow tubes. A center divider facilitates two separate compartments and allows control over pack densities within each compartment while allowing blood to move in a planar manner throughout the device.

Abstract: A filter cartridge using hollow fiber tubes is provided in a housing and configuration constructed and arranged to fit most commercial filter housing systems without modification. The hollow fiber cartridge provide a multiple improvement in filtering capacity and life before requiring replacement over prior units.

Abstract: A method for non-destructive testing for approximation of oxygen transmission in hollow fiber blood oxygenators or the like is provided which method includes passing a first fluid at a predetermined temperature and volume flow rate through the hollows of the fibers and a second fluid at a second predetermined input temperature and volume flow rate across the outside of the fibers and measuring the heat rise or fall of the fluids and comparing the results with standards for a given blood oxygenator device.

Abstract: A venous reservoir for use in cardiotomy bypasses comprising a flexible, variable capacity bag having a vertical seal positioned between the outlets and inlets along the lower seal line. The vertical seal line is positioned off-center such that the velocity of blood decreases as it passes the top of said seal line and towards the lower outlet to increase the removal of bubbles from the blood. All ports serving the reservoir are constructed without internal projections into the reservoir to decrease the possibility of thrombosis. The upper and lower edges of the reservoir are looped to receive horizontal rods slidably attached to a vertical support. Adjustment of the distance between the rods varies the volume possible within the reservoir.

Abstract: An implant device for introduction of insulin into the peritoneal cavity which permits a flexible catheter to be removed and replaced without invasive surgery. The catheter is passed through a substantially rigid percutaneous body and a distally extending catheter conduit which together form a continuous conduit from the body exterior through the peritoneal wall. A polytetrafluoroethylene polymer sleeve allows tissue ingrowth to secure the body to the epidermis. A polyethylene terephthalate portion of the sleeve provides tissue ingrowth to stabilize the implant and prevent extrusion from the dermis. The catheter is associated with the percutaneous tubular body so as to be removable and replaceable through the conduit thereformed after implantation. The catheter preferably terminates within the interior cavity of the percutaneous body and is sealed from the environment by means of a septum closure within the device cavity.

Abstract: Improvements and accessories for a septum closed T-shaped blood access device adapted for implantation into a patient. The implantable device has a stem portion extending above the skin of the patient and defining a septum closed opening into the device. The improvements include an improved septum having a groove in the side thereof encircling the septum and an elastomeric ring carried within the side groove, an improved needle assembly which provides access to the circulatory system through the septum, and a flexible cap for sealing the stem of the implantable device from the outside atmosphere which may be fitted in place or removed without the necessity of specialized tools.

Abstract: A system and process for preparation of dialysis solution from dry chemicals and water on a large scale batch basis. The required amount of water is metered into a dialysis solution tank. Water from the tank is pumped into a spray head which is positioned above a shipping drum containing predetermined amounts of chemicals. Water rains down on the chemicals dissolving and/or entraining the same and the resulting slurry is returned to the dialysate tank as a slurry by means of a pickup wand and suction source. The liquid and chemicals in the dialysis solution tank are continually cycled until all the chemicals in the drum have been removed. Typically, an additional drum containing other kinds of chemicals is then added to the dialysis solution tank in the same manner. Circulation of the solution is continued within the tank until a fully uniform solution results.

Abstract: A machine for reprocessing catheters of the type having a double lumen, one of which leads to a balloon. A used catheter is sealed within a cassette which in turn is connected by multiple ports to a cleaning side of the machine. Cleaning solution is flushed through the inside and outside of the catheter. The balloon integrity is tested by adding step wise volume additions and monitoring the pressure. The data generated is compared to a standard curve for new catheters. The cleaned, sterile catheter is then rinsed to remove all traces of sterilant. Sterile saline is alternatively flushed through the cassette and catheter. The balloon is again tested for leaks. No portion of the rinse side of the machine requires sterilizing except for the disposable tubing set and saline source. The rinsed, clean and sterile catheter is removed from the cassette for reuse.