Patents Assigned to Miris Bio Corporation
  • Intravascular delivery of nucleic acid
    Patent number: 7396821
    Abstract: Disclosed is a process for transfecting genetic material into a mammalian cell to alter endogenous properties of the cell. The process comprises designing a polynucleotide for transfection. Then the polynucleotide is inserted into a mammalian blood vessel. Prior to insertion, subsequent to insertion, or concurrent with insertion the permability of the vessel is increased using an exterior cuff and immunosuppression is applied thereby the genetic material is delivered to the parenchymal cell.
    Type: Grant
    Filed: November 6, 2000
    Date of Patent: July 8, 2008
    Assignee: Miris Bio Corporation
    Inventors: Jon A. Wolff, Vladimir G. Budker