Abstract: Use of a polyamino acid as an adjuvant; an application of a polyamino acid as an adjuvant in the production of a vaccine; a vaccine comprising a polyamino acid as an adjuvant; a biodegradable nanoparticle having a virus antigen immobilized thereon; and a vaccine comprising the biodegradable nanoparticle.
Abstract: Use of a polyamino acid as an adjuvant; an application of a polyamino acid as an adjuvant in the production of a vaccine; a vaccine comprising a polyamino acid as an adjuvant; a biodegradable nanoparticle having a virus antigen immobilized thereon; and a vaccine comprising the biodegradable nanoparticle.
Type:
Grant
Filed:
April 19, 2006
Date of Patent:
August 31, 2010
Assignees:
Taiho Pharmaceutical Co., Ltd., Mitsuru Akashi, Masanori Baba
Abstract: A rigid polymer has: a homopolymer of one of a polymerizable bio-derived rigid compound having two or more reactive functional groups, a derivative of the bio-derived rigid compound, a hydrolyzed substance of the bio-derived rigid compound, a derivative of the hydrolyzed substance of the bio-derived rigid compound and the substances extracted from the bio resources, or copolymers of two or more of these compound, derivatives, and substances.
Abstract: A method for preparing a hydroxyapatite composite is disclosed. This method comprises alternately soaking a matrix which has been made hydrophilic at least on its surface, in a calcium ion aqueous solution containing calcium ions and substantially free of phosphate ions and in a phosphate ion aqueous solution containing phosphate ions and substantially free of calcium ions to securely form hydroxyapatite at least on the surface of the matrix. Also disclosed is a biocompatible material composed of the hydroxyapatite composite obtained by the method.
Abstract: The present invention relates to an antiviral raw material having mannose-binding type lectin bound, through a hydrophilic high-molecular chain, to a base material composed of a hydrophobic high-molecular chain. The raw material has excellent shape stability and at the same time has excellent antiviral activity so that it can be used in a wide range of fields.