Patents Assigned to Molecular Genetics, Inc.
  • Herbicide resistance in plants
    Patent number: 4761373
    Abstract: This invention is directed to the production of plants, plant tissues and plant seeds which are resistant to inhibition by an herbicide which normally inhibits the growth and development of those plants, plant tissues and plant seeds. In particular this invention is directed to altered acetohydroxyacid synthase enzymes which are resistant to inhibition by herbicides which normally inhibit the activity of the synthase before such alteration. This invention further relates to genes encoding such enzymes, and to processes for utilizing these novel genes and enzymes. Further products of the invention include plants, plant tissues and seeds which exhibit resistance to such herbicides resulting from expression of genes encoding herbicide resistant acetohydroxyacid synthase enzyme.
    Type: Grant
    Filed: August 10, 1984
    Date of Patent: August 2, 1988
    Assignee: Molecular Genetics, Inc.
    Inventors: Paul C. Anderson, Kenneth A. Hibberd
  • Vaccines against rift valley fever virus
    Patent number: 4735800
    Abstract: Methods and compositions are provided for the cloning and expression of Rift Valley Fever Virus genes in single cell host organisms. Also described are methods for culturing these novel single-cell organisms to produce Rift Valley Fever Virus gene gene products which may be formulated for use as products which may be formulated for use as immunogens in vaccines to protect against Rift Valley Fever Virus infections.
    Type: Grant
    Filed: August 23, 1984
    Date of Patent: April 5, 1988
    Assignee: Molecular Genetics, Inc.
    Inventors: Marc S. Collett, Anthony F. Purchio
  • Production of reverse transcriptase
    Patent number: 4663290
    Abstract: Methods are described for the production of the .beta.-subunit of reverse transcriptase using recombinant DNA techniques. Methods and compositions are described for cloning and expressing the gene coding for the .beta.-subunit of reverse transcriptase and characterizing and isolating the gene product. The recombinant plasmids constructed herein contain the necessary signals and controls for efficient expression of the reverse transcriptase gene in bacteria and other microorganisms. The isolated reverse transcriptase gene product is a functional, metabolically stable and biologically active protein.
    Type: Grant
    Filed: January 21, 1982
    Date of Patent: May 5, 1987
    Assignee: Molecular Genetics, Inc.
    Inventors: John H. Weis, John S. Salstrom
  • Use of monoclonal antibodies against bacterial adhesins
    Patent number: 4652448
    Abstract: Monoclonal antibodies specific for surface antigens of bacteria which act as adhesins between prokaryotic and eukaryotic cells and, in particular, K-99 pili, and methods for production thereof are described. These monoclonal antibodies may be used for the prophylactic and therapeutic treatment of diseases induced by adhesin-bearing pathogens in animals and humans, and for the diagnostic identification of adhesin-bearing bacteria.
    Type: Grant
    Filed: December 6, 1983
    Date of Patent: March 24, 1987
    Assignee: Molecular Genetics, Inc.
    Inventor: Peter L. Sadowski
  • Production of monoclonal antibodies against bacterial adhesins
    Patent number: 4443549
    Abstract: Monoclonal antibodies specific for surface antigens of bacteria which act as adhesins between prokaryotic and eukaryotic cells and, in particular, K-99 pili, and methods for production thereof are described. These monoclonal antibodies may be used for the prophylactic and therapeutic treatment of diseases induced by adhesin-bearing pathogens in animals and humans, and for the diagnostic identification of adhesin-bearing bacteria.
    Type: Grant
    Filed: October 7, 1982
    Date of Patent: April 17, 1984
    Assignee: Molecular Genetics, Inc.
    Inventor: Peter L. Sadowski