Abstract: A method of manufacturing feather-filled items of clothing includes the following steps: preparing at least one mold provided with first concavities of shape substantially complementary to a respective padded cambered region of at least one portion of the item of clothing to be obtained; and associating a first sheet of deformable material with the mold. The method further includes deforming the first sheet against the mold so as to obtain, on the first sheet, second concavities that substantially correspond to the first concavities of the mold. Then, each second concavity of the first sheet is filled with down, and a second sheet is anchored to the first sheet. The semi-finished product is removed from the mold.