Patents Assigned to Montech Medical Developments Pty. Ltd.
  • Method for detecting rheumatoid arthritis employing the CB10 peptide of mammalian type II collagen as an antigen
    Publication number: 20040157265
    Abstract: An highly specific and sensitive approach to detecting antibodies to collagen in a biological sample entails contacting the sample with an antigen that comprises the CB10 peptide of mammalian type II collagen, or with an antibody-binding fragment of that peptide, under conditions conducive to formation of an antibody-antigen complex, which then is detected.
    Type: Application
    Filed: February 9, 2004
    Publication date: August 12, 2004
    Applicants: MONTECH MEDICAL DEVELOPMENTS PTY. LTD., RONDOLE PTY. LTD.
    Inventors: Andrew Cook, Merrill Rowley, Ian Mackay
  • Method for detecting rheumatoid arthritis employing the CB10 peptide of mammalian type II collagen as an antigen
    Patent number: 6706490
    Abstract: A predictive test for rheumatoid arthritis comprises the detection of antibodies to collagen in a biological sample from a patient by contacting the biological sample with an antigen comprising the CB10 peptide of mammalian type II collagen, or an antibody-binding fragment or variant thereof, for a time and under conditions for an antibody-antigen complex to form, and detecting the antibody-antigen complex, for example by immunoassay. A diagnostic test kit is also disclosed.
    Type: Grant
    Filed: November 20, 2000
    Date of Patent: March 16, 2004
    Assignees: Montech Medical Developments Pty. Ltd., Rondole Pty. Ltd.
    Inventors: Andrew Cook, Merrill Rowley, Ian Mackay
  • Expression in yeast of antigenically active, recombinant hybrid glutamic acid decarboxylase
    Patent number: 6165738
    Abstract: An antigenically active hybrid glutamic acid decarboxylase (GAD) comprising an amino-terminal moiety derived from the GAD67 isoform linked directly or indirectly with a middle and carboxy-terminal moiety derived from the GAD65 isoform, and production thereof as a recombinant protein by expression in eukaryotic host cells, particularly yeasts.
    Type: Grant
    Filed: September 13, 1999
    Date of Patent: December 26, 2000
    Assignees: Montech Medical Developments Pty. Ltd., Rondole Pty. Ltd.
    Inventors: Ian Reay Mackay, Merrill Joy Rowley, Paul Zev Zimmet, Brian Corner, Ruby Law, Khay-Lin Teoh