Abstract: Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on the substrate, wherein the coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within the coating and on the substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of the medical device in the body of the subject a portion of the pharmaceutical agent and/or active biological agent is delivered at the intervention site along with at least a portion of the polymer and/or a at least a portion of the pharmaceutical carrying agents.
Type:
Application
Filed:
August 8, 2023
Publication date:
November 30, 2023
Applicant:
MT Acquisition Holdings LLC
Inventors:
James B. McClain, Charles Douglas Taylor, Brett G. Zani, John Neet, Timothy Charles Kiorpes
Abstract: Provided herein is a coated coronary stent, comprising: a. stent framework; b. a plurality of layers deposited on said stent framework to form said coronary stent; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form.
Type:
Application
Filed:
February 13, 2023
Publication date:
June 15, 2023
Applicant:
MT Acquisition Holdings LLC
Inventors:
James B. McClain, Charles Douglas Taylor
Abstract: A method for preparing a laminate coronary stent comprising: providing a stent framework; and depositing a plurality of layers on said stent framework to form said laminate coronary stent; wherein at least one of said layers comprises a bioabsorbable polymer.
Type:
Grant
Filed:
February 7, 2020
Date of Patent:
August 30, 2022
Assignee:
MT Acquisition Holdings LLC
Inventors:
James B. McClain, Charles Douglas Taylor, Robert Rabiner
Abstract: Stent delivery systems having improved deliverability comprising an elongate member having an inflation lumen and a guidewire lumen therein; a balloon having an interior that is in fluid communication with the inflation lumen; and a stent comprising a coating mounted on the balloon. Methods for making stent delivery systems having improved deliverability. Methods for delivering two stent delivery systems concurrently through a guiding catheter, each stent delivery system comprising elongate member having an inflation lumen and a guidewire lumen therein, a balloon having an interior that is in fluid communication with the inflation lumen, and a stent comprising a coating mounted on the balloon. Stent coatings may comprise a pharmaceutical agent at least a portion of which is in crystalline form.
Type:
Grant
Filed:
January 26, 2011
Date of Patent:
June 28, 2022
Assignee:
MT Acquisition Holdings LLC
Inventors:
James B. McClain, Douglas Taylor, David Enscore
Abstract: A method for depositing a coating comprising a polymer and at least two pharmaceutical agents on a substrate, comprising the following steps: providing a stent framework; depositing on said stent framework a first layer comprising a first pharmaceutical agent; depositing a second layer comprising a second pharmaceutical agent; Wherein said first and second pharmaceutical agents are selected from two different classes of pharmaceutical agents.
Type:
Application
Filed:
April 29, 2021
Publication date:
August 12, 2021
Applicant:
MT Acquisition Holdings LLC
Inventors:
James P. DeYoung, Charles Douglas Taylor, James B. McClain, Clint Smoke, Mike Cole