Patents Assigned to Nanjing Yoko Biomedical R & D Ltd.
  • Histone deacetylase inhibitors and synthetic method thereof and use thereof in manufacture of medicaments
    Patent number: 8933195
    Abstract: The invention provides histone deacetylase (HDAC) inhibitors shown as Formula I, where R1 to R8 are as defined in the specification. The invention also provides methods for synthesis of these compounds and applications of these compounds in preparing pharmaceuticals for preventing or treating mammal diseases related to the dysregulation of HDAC.
    Type: Grant
    Filed: February 23, 2012
    Date of Patent: January 13, 2015
    Assignees: Nanjing Yoko Biomedical R & D Ltd., Nanjing Xingang Medical Co., Ltd., Nanjing Yoko Pharmaceutical Co., Ltd.
    Inventors: Sheng Jiang, Shang Li, Zhiyi Yao, Yiwu Yao, Feng Zhang, Yang Chao, Hai Ye, Min Chen
  • HISTONE DEACETYLASE INHIBITORS AND SYNTHETIC METHOD THEREOF AND USE THEREOF IN MANUFACTURE OF MEDICAMENTS
    Publication number: 20140243501
    Abstract: The invention provides histone deacetylase (HDAC) inhibitors shown as Formula I, where R1 to R8 are as defined in the specification. The invention also provides methods for synthesis of these compounds and applications of these compounds in preparing pharmaceuticals for preventing or treating mammal diseases related to the dysregulation of HDAC.
    Type: Application
    Filed: February 23, 2012
    Publication date: August 28, 2014
    Applicants: NANJING YOKO BIOMEDICAL R & D LTD. [CN/CN], NANJING XINGANG MEDICAL CO., LTD. [CN/CN], NANJING YOKO PHARMACEUTICAL CO., LTD. [CN/CN]
    Inventors: Sheng Jiang, Shang Li, Zhiyi Yao, Yiwu Yao, Feng Zhang, Yang Chao, Hai Ye, Min Chen