Abstract: Cell deposition and staining apparatuses and methods are disclosed herein. In particular, the deposition and staining apparatuses disclosed herein provide low-volume, automated bench top systems for depositing and staining cellular samples on a cytological slide. An example deposition and staining apparatus includes a housing having an access door; a substrate processing holder located within the housing configured to hold one or more substrates and/or one or more substrate cartridges, wherein the substrate processing holder is accessible when the access door is in an open configuration; at least one opening located at least partially above at least a portion of the substrate processing holder; a spray nozzle configured to dispense a gaseous substance into the substrate processing area; a user interface configured receive an input from a user, and in response to receiving the input, cause execution of a pre-programmed protocol; and a waste and/or reagent holder element.
Type:
Grant
Filed:
July 10, 2019
Date of Patent:
August 8, 2023
Assignees:
NANOCYTOMICS, LLC, NORTHWESTERN UNIVERSITY
Inventors:
Hariharan Subramanian, Michael Verleye, Micah Litow, Justin R. Derbas, Sergey Rozhok, John Hart, Chester Henderson, Rebecca Bartel, Nathan Ray, Anthony White
Abstract: Systems and methods that enable automated spray deposition of biological specimens carried on microscope slides are described herein. Aspects of the technology are directed, for example, to automated specimen deposition systems and methods of generating high-quality, reproducible specimen-bearing microscope slides in automated processing systems.
Type:
Grant
Filed:
May 23, 2022
Date of Patent:
February 7, 2023
Assignees:
NanoCytomics, LLC, Northwestern University
Abstract: Automated cell staining systems and methods are disclosed herein. In particular, the staining systems disclosed herein provide low-volume, automated bench top staining systems for staining biological samples contained on a cytological slide.
Type:
Grant
Filed:
June 16, 2017
Date of Patent:
October 4, 2022
Assignees:
NanoCytomics, LLC, Northwestern University
Inventors:
Sergey Rozhok, Justin R. Derbas, Jarema Czarnecki, Hariharan Subramanian
Inventors:
John Hart, Micah Litow, Hariharan Subramanian, Justin R. Derbas, Jerry Czarnecki, Sergey Rozhok, Michael Verleye, Mirela Wohlford, Anthony White, Simon Spence, Nathan Ray, Kyle Wolf