Abstract: A device suitable for guiding a trajectory of a surgical shunt or needle comprising two protractors on a curved frame configured to fit over, or attach to, the skull of a patient, wherein the two protractors are respectively oriented in a circular dimension and anterior-posterior/medio-lateral directions. A method for using the device to guide a surgical needle, probe, shunt or other instrument during surgery.

Abstract: A plant-based composition containing an alcohol extract of Tecoma species (e.g. Tecoma stans) and an exogenous carrier and/or excipient. Also provided is a composition including a mixture of three acids, namely corosolic acid, oleanolic acid, and ursolic acid, which can be found in the Tecoma species. Methods of treating skin lesions (e.g. warts, corns, calluses, and umbilical granulomas) and reducing symptoms associated with the skin lesions using such compositions are specified.

Abstract: A method for isolating a protein complex comprising BCL10 and at least one, preferably all, of ROS1, LSD1, BTK, KU80, KU70, CUL4A, IMP3, thioredoxin, hTID1, DAP3, CDK1/CDC2, PRL1/PTP4A1 or NM23. Methods for using this complex to diagnose or prognose diseases including diabetes, obesity, cancer, neurodegenerative disease or inflammatory diseases associated with activation of NF-?B. Methods for distinguishing lean, obese and diabetic subjects based on expression of BCL10 and its ligands are also disclosed. The invention also pertains to pharmaceutical compositions comprising ligands for BCL10 or other components of this complex or agents such as siRNA or miRNA that regulate the expression of the protein components of this complex.

Abstract: Methods for medical diagnosis of heat-related health conditions including heatstroke, compositions comprising RNA or protein biomarkers for heatstroke and heat-associated conditions, probes and primers and antibodies to such biomarkers.

Abstract: A steerable endovascular catheter which can be used and for diagnosis and endovascular treatment of vascular diseases. Methods of diagnosis and endovascular treatment comprising steering the catheter through vasculature of a patient.

Abstract: A system for quickly determining antibiotic sensitivity of a microorganism comprising a triangular-shaped plate and cover for culturing, recovering, and re-suspending recovered microbial colonies and a second triangular-shaped plate comprising a non-liquid medium cut with concentric trenches over which the re-suspended microbial colonies are distributed by centrifugation and contacted with antimicrobial strips or disks.

Abstract: The invention pertains to a method for temporarily conferring advantageous cancer cell phenotypes, such as a higher proliferation rate, resistance to apoptosis and cell death, and resistance to endogenous factors that inhibit cell growth, on non-cancer cells that help repair and regenerate damaged tissues.

Abstract: The invention pertains to a medical device: an ECMO (extracorporeal membrane oxygenation) catheter which can be used during right heart and lung failure. It pertains to a dual lumen catheter with a single port of entry which when in place bypasses the right heart and lungs while completing the veno-arterial circuit.

Abstract: A positioning splint for safely and securely positioning a pediatric patient into a lithotomy position. The splint comprises a toroid, wedge-shaped splint having an anterior and posterior jaw which is attached to shoulder straps or a jacket/vest that holds the splint in place during use. The wedge splint and shoulder attachments are padded. The wedge splint may have a disposable covering. Methods of using the splint to position a patient for urinary catheterization as well as for other procedures, exams and surgeries requiring unobstructed access to the perineal and anorectal areas. Additional wrist/hand and ankle/leg straps are used for conscious patients who are uncooperative or incompetent patients or in the case of a patient with involuntary movement disorders.

Abstract: A bifunctional expandable stent delivery assembly having a bifunctional expandable stent, a breakable cover, and a balloon. The bifunctional expandable stent has a balloon-expandable body portion and a self-expandable trumpet portion. The breakable cover fits over only the self-expandable trumpet portion and prevents self-expansion. The balloon is used to expand the balloon-expandable portion, which breaks the breakable cover and allows the self-expandable trumpet portion to self-expand. A method of stenting a patient using the bifunctional expandable stent delivery assembly is also provided.

Abstract: A ethically sound, safe, feasible, and cost-effective microsurgery practice technique that can easily be practiced by trainees having different skill levels and an adjustable device for holding and manipulating vascular tissue during microsurgery practice, especially for practicing anastomoses.

Abstract: A system comprising a stent and a stent delivery device configured with a tiny intravascular ultrasound (“IVUS”) transducer on the tip of a delivery catheter which can image the interior of blood vessels. Methods for treating ostial or bifurcated lesions using the system.

Abstract: A hybrid ID system for a medical practitioner and patient care includes a hybrid electronic ID/key having a transmitter device having circuitry for storing ID data and transmitting a signal containing the ID data, and a key having a predetermined shape on a surface of the hybrid electronic ID/key. A radio frequency receptor device having circuitry, storing location information, that detects the signal containing ID data, a matching detection section configured to match the predetermined shape of the key, and a movement tracking portion that tracks movement of the predetermined shape as the key is rotated. A computer system including a patient database is configured to receive the ID data in conjunction with the location information from the radio frequency receptor device when the predetermined shape is completely rotated to a final position, and store the ID data, location information, together with patient data associated with the location.

Abstract: A blood collection tube for physically separating the plasma and red blood cell fractions of a centrifuged sample is described. The blood collection tube has an elastomeric sleeve with rigid tube segments at both ends. Following blood collection and centrifugation, the elastomeric sleeve may be twisted to constrict its inner diameter and physically separate the two fractions. The blood collection tube may be secured in this position with a pin and a clamp, and further with an adhesive tape with pH paper. This enables blood samples to be transferred over long distances to a central lab facility without spoiling.

Abstract: An apparatus and method for testing dissolution properties of a drug, especially anti-inflammatory drugs administered by aerosol into the respiratory system. The apparatus shortens the time it takes for a drug to dissolve and thus provides for rapid testing of new drugs for quality control as well as for regulatory purposes. It is suitable for evaluating bioequivalence or to study the pharmacokinetics of drugs administered into the respiratory system. This method shortens dissolution times for testing a drug to about 10 and 20 minutes and thus provides for rapid testing.

Abstract: A hybrid ID system for a medical practitioner and patient care includes a hybrid electronic ID/key having a transmitter device having circuitry for storing ID data and transmitting a signal containing the ID data, and a key having a predetermined shape on a surface of the hybrid electronic ID/key. A radio frequency receptor device having circuitry, storing location information, that detects the signal containing ID data, a matching detection section configured to match the predetermined shape of the key, and a movement tracking portion that tracks movement of the predetermined shape as the key is rotated. A computer system including a patient database is configured to receive the ID data in conjunction with the location information from the radio frequency receptor device when the predetermined shape is completely rotated to a final position, and store the ID data, location information, together with patient data associated with the location.

Abstract: A peptide that binds to the Si spike protein of Middle East Respiratory syndrome coronavirus or MERS-CoV and a method for inhibiting infection of a subject exposed to or having MERS-CoV by administering the peptide.

Abstract: Maillard reaction products produced by heating carbohydrates with one or more amino acids (e.g., lysine), at basic pH and for a selected reaction time at a particular concentration in solution, can exhibit inhibitory activity against Aggregatibacter actinomycetemcomitans.

Abstract: A hybrid ID system for a medical practitioner and patient care includes a hybrid electronic ID/key having a transmitter device having circuitry for storing ID data and transmitting a signal containing the ID data, and a key having a predetermined shape on a surface of the hybrid electronic ID/key. A radio frequency receptor device having circuitry, storing location information, that detects the signal containing ID data, a matching detection section configured to match the predetermined shape of the key, and a movement tracking portion that tracks movement of the predetermined shape as the key is rotated. A computer system including a patient database is configured to receive the ID data in conjunction with the location information from the radio frequency receptor device when the predetermined shape is completely rotated to a final position, and store the ID data, location information, together with patient data associated with the location.

Abstract: A finger protector to prevent lacerations to the fingers of a surgeon during suturing. A kit comprising the finger protector and a method of using it during surgery.