Abstract: There are disclosed sterilant compositions having improved biocompatibility comprising a sterilant such as sodium chlorite, an acid such as citric acid, and a buffer such as sodium bicarbonate, the compositions forming an isotonic solution with pH of approximately 7.3.The compositions are particularly useful for cleansing and sterilizing kidney hemodialysis apparatus with minimal disruption of the protein layer which forms on the internal surface of the hollow fibers of a dialysis membrane when a patient is undergoing treatment with the apparatus thus establishing improved biocompatibility between patient and apparatus. The compositions are also useful in other areas of technology, such as, for example, food and wine making technologies.
Abstract: A dialysis module for use with a variety of single pass or single pass-recirculating artificial kidney dialyzers as desired. The apparatus has quick disconnects to allow attachment of a single pass kidney dialyzer or shunt tube so that a single housing can be used to provide two entirely different modes of operation as selected. A clear canister forms a part of the dialysis flow path in both modes of operation to enable rapid detection of blood leaks in either mode of operation.
Type:
Grant
Filed:
February 18, 1975
Date of Patent:
October 25, 1977
Assignee:
National Medical Care, Inc.
Inventors:
Richard A. Friedrich, Robert L. MacNeill
Abstract: A dialysis module for use with a variety of single pass or single pass-recirculating artificial kidney dialyzers as desired. The apparatus has quick disconnects to allow attachment of a single pass kidney dialyzer or blocking off of a portion of a fluid conduit when a coil dialyzer is used so that a single housing can be used to provide two entirely different modes of operation as selected. A clear canister preferably forms a part of the dialysis flow path in both modes of operation to enable rapid detection of blood leaks in either mode of operation. An aspirator is associated with a recirculating pump to provide negative pressure to dialysate in the flow path when a single pass dialyzer is used while only the recirculating pump is necessary during single pass-recirculating dialysis.
Type:
Grant
Filed:
September 30, 1974
Date of Patent:
May 31, 1977
Assignee:
National Medical Care, Inc.
Inventors:
Richard A. Friedrich, Robert L. MacNeill