Patents Assigned to National University Corporation Shimane University
  • Patent number: 11938254
    Abstract: The present invention provides a hollow fiber membrane oxygenator comprising a housing comprising a blood flow path; a blood inlet port and a blood outlet port disposed in the housing so as to allow blood to flow through the blood flow path; a gas exchange part comprising a bundle of a plurality of hollow fiber membranes disposed in the blood flow path, a gas inflow port and a gas outflow port provided in the housing so as to allow an oxygen-containing gas to flow through lumens of the hollow fiber membranes, and a gas temperature control part for adjusting the temperature of a gas flowing through the lumens of the hollow fiber membranes.
    Type: Grant
    Filed: March 26, 2019
    Date of Patent: March 26, 2024
    Assignee: NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
    Inventor: Teiji Oda
  • Publication number: 20230324349
    Abstract: One mode of a method for analyzing acylcarnitine according to the present invention is a method for analyzing C5 acylcarnitine using a tandem mass spectrometer, the method including: a measurement step of performing MRM measurement on a specimen according to at least one of MRM transitions of m/z 24>187, m/z 246>57, m/z 246>41, and m/z 246>29; and a processing step of distinguishing between isovalerylcarnitine and pivaloylcarnitine which is an isomer of isovalervicarnitine in the specimen or determining whether or not C5 acylcarnitine in the specimen includes pivaloylcarnitine, using a measurement result obtained in the measurement step. This makes it possible to satisfactorily distinguish between isovalerylcarnitine and pivaloylcarnitine, which have been conventionally difficult to distinguish.
    Type: Application
    Filed: August 24, 2021
    Publication date: October 12, 2023
    Applicants: Shimadzu Corporation, NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
    Inventors: Takanari HATTORI, Jun WATANABE, Misa TANAKA, Hironori KOBAYASHI, Yoshitomo NOTSU
  • Publication number: 20230122509
    Abstract: Provided is a method by which the disaccharides derived from glycosaminoglycans can be analyzed in a stable and highly reproduceable manner. A method for analyzing a glycosaminoglycan according to the present invention includes: a first process for producing a plurality of kinds of disaccharides derived from a glycosaminoglycan in a biological sample by adding a plurality of kinds of glycosaminoglycan-specific enzymes to the biological sample: and a second process for separating and analyzing the plurality of kinds of disaccharides by a liquid chromatography-mass spectrometry method, where a column used for liquid chromatography in the liquid chromatography-mass spectrometry method is a column packed with a stationary-phase support to which an amide group as a functional group is bound, or a column packed with a stationary-phase support to which an adamantyl group as a functional group is bound.
    Type: Application
    Filed: October 14, 2021
    Publication date: April 20, 2023
    Applicants: SHIMADZU CORPORATION, NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
    Inventors: Takanari HATTORI, Jun WATANABE, Tetsuo IIDA, Misa TANAKA, Hironori KOBAYASHI, Shunji TOMATSU
  • Publication number: 20210015985
    Abstract: The present invention provides a hollow fiber membrane oxygenator comprising a housing comprising a blood flow path; a blood inlet port and a blood outlet port disposed in the housing so as to allow blood to flow through the blood flow path; a gas exchange part comprising a bundle of a plurality of hollow fiber membranes disposed in the blood flow path, a gas inflow port and a gas outflow port provided in the housing so as to allow an oxygen-containing gas to flow through lumens of the hollow fiber membranes, and a gas temperature control part for adjusting the temperature of a gas flowing through the lumens of the hollow fiber membranes.
    Type: Application
    Filed: March 26, 2019
    Publication date: January 21, 2021
    Applicant: NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
    Inventor: Teiji ODA
  • Patent number: 10780127
    Abstract: The present invention provides fermented milk having a high angiotensin converting enzyme inhibition activity, a high hypotensive activity and/or a high stroke-preventing activity. The present invention also provides a method for producing fermented milk having a high angiotensin converting enzyme inhibition activity, a high hypotensive activity and/or a high stroke-preventing activity and a method for producing Tyr-Pro, each of which is characterized by comprising fermenting milk with a mushroom.
    Type: Grant
    Filed: June 22, 2017
    Date of Patent: September 22, 2020
    Assignees: NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY, NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
    Inventors: Kenji Okamoto, Toru Nabika
  • Patent number: 10760993
    Abstract: A measurement method for measuring an effective refractive index difference between two propagation modes of a multimode fiber is provided. The method includes: measuring a first Brillouin frequency shift ?1 by specifying a frequency having a lowest-frequency peak out of peaks in a first frequency spectrum of scattered light in a first propagation mode; measuring a second Brillouin frequency shift ?2 by specifying a frequency having a lowest-frequency peak out of peaks in a second frequency spectrum of scattered light in a second propagation mode; and calculating an effective refractive index difference ?neff in accordance with ?neff=(?1??2)/(2kVL) with use of the first Brillouin frequency shift ?1, the second Brillouin frequency shift ?2, a predetermined wave number k of light in a vacuum, and a predetermined constant VL.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: September 1, 2020
    Assignees: Fujikura Ltd., NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
    Inventors: Ryo Maruyama, Nobuo Kuwaki, Fumihiko Ito
  • Patent number: 10533732
    Abstract: A headlight (1) for a healthcare worker includes: a base part (10), which has a U-shape, is configured to come into abutment, at a center part of the base part (10), with a back side of a head and neck part of a wearer, and includes a right end part (11) and a left end part (11), each of which is configured to be hung on an upper part of an ear so that the base part (10) is retained on a head; a light source device (20), which extends from both or any one of a vicinity of the end parts (11), includes LEDs as light sources, and is configured to illuminate a region in front of the head; and a controller (30) configured to control an illumination state of the light source device (20). The controller (30) is configured to light the light source device (20) when the base part (10) reaches a predetermined depression angle with a standing state of the wearer serving as a reference.
    Type: Grant
    Filed: January 18, 2017
    Date of Patent: January 14, 2020
    Assignees: National University Corporation Shimane University, Do Light Co., Ltd.
    Inventors: Morihiko Nakamura, Makie Yano, Hiroyuki Tanaka
  • Publication number: 20190343884
    Abstract: The present invention provides fermented milk having a high angiotensin converting enzyme inhibition activity, a high hypotensive activity and/or a high stroke-preventing activity. The present invention also provides a method for producing fermented milk having a high angiotensin converting enzyme inhibition activity, a high hypotensive activity and/or a high stroke-preventing activity and a method for producing Tyr-Pro, each of which is characterized by comprising fermenting milk with a mushroom.
    Type: Application
    Filed: June 22, 2017
    Publication date: November 14, 2019
    Applicants: NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY, NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
    Inventors: Kenji OKAMOTO, Toru NABIKA
  • Patent number: 10458881
    Abstract: This internal pressure loading system includes an internal pressure loading device and an information processing device. The internal pressure loading device is set at an inner face of a pipe, and includes a load meter which detects the load applied to the inner face of the pipe and a displacement meter which detects the deformation amount of the pipe. When the internal pressure loading device is expanded so as to increase the load to be detected by the load meter, the width of the pipe at which the displacement meter is located is reduced. On the basis of the load detected by the load meter and the deformation amount detected by the displacement meter, the information processing device evaluates the remaining strength of the pipe.
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: October 29, 2019
    Assignees: NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY, NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
    Inventors: Masahiro Hyodo, Hidehiko Ogata, Naoki Kawamura, Tsuguhiro Nonaka, Masayuki Ishii
  • Publication number: 20190226941
    Abstract: A measurement method for measuring an effective refractive index difference between two propagation modes of a multimode fiber is provided. The method includes: measuring a first Brillouin frequency shift v1 by specifying a frequency having a lowest-frequency peak out of peaks in a first frequency spectrum of scattered light in a first propagation mode; measuring a second Brillouin frequency shift v2 by specifying a frequency having a lowest-frequency peak out of peaks in a second frequency spectrum of scattered light in a second propagation mode; and calculating an effective refractive index difference ?neff in accordance with ?neff=(v1?v2)/(2kVL) with use of the first Brillouin frequency shift v1, the second Brillouin frequency shift v2, a predetermined wave number k of light in a vacuum, and a predetermined constant VL.
    Type: Application
    Filed: May 1, 2017
    Publication date: July 25, 2019
    Applicants: FUJIKURA LTD., NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
    Inventors: Ryo Maruyama, Nobuo Kuwaki, Fumihiko Ito
  • Patent number: 10301542
    Abstract: A scintillator includes a support substrate, an emission layer formed on the substrate, made of ZnO with impurities added to have an electron concentration of 2×1019 cm?3 or more and 2×1020 cm?3 or less, and for generating scintillation light in response to incidence of radiation, a protective layer formed on the emission layer and made of a material having a hand gap wider than that of ZnO, and a metal layer formed on the protective layer. The support substrate is made of a material transmitting the scintillation light generated in the emission layer. Further, the metal layer functions as a reflection layer for reflecting the scintillation light from the emission layer.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: May 28, 2019
    Assignees: NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY, HAMAMATSU PHOTONICS K.K.
    Inventors: Yasuhisa Fujita, Minoru Kondo
  • Publication number: 20190023982
    Abstract: A scintillator includes a support substrate, an emission layer formed on the substrate, made of ZnO with impurities added to have an electron concentration of 2×1019 cm?3 or more and 2×1020 cm?3 or less, and for generating scintillation light in response to incidence of radiation, a protective layer formed on the emission layer and made of a material having a band gap wider than that of ZnO, and a metal layer formed on the protective layer. The support substrate is made of a material transmitting the scintillation light generated in the emission layer. Further, the metal layer functions as a reflection layer for reflecting the scintillation light from the emission layer.
    Type: Application
    Filed: December 9, 2016
    Publication date: January 24, 2019
    Applicants: National University Corporation Shimane University, HAMAMATSU PHOTONICS K.K.
    Inventors: Yasuhisa FUJITA, Minoru KONDO
  • Publication number: 20170131175
    Abstract: This internal pressure loading system includes an internal pressure loading device and an information processing device. The internal pressure loading device is set at an inner face of a pipe, and includes a load meter which detects the load applied to the inner face of the pipe and a displacement meter which detects the deformation amount of the pipe. When the internal pressure loading device is expanded so as to increase the load to be detected by the load meter, the width of the pipe at which the displacement meter is located is reduced. On the basis of the load detected by the load meter and the deformation amount detected by the displacement meter, the information processing device evaluates the remaining strength of the pipe.
    Type: Application
    Filed: January 25, 2017
    Publication date: May 11, 2017
    Applicants: NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY, NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
    Inventors: Masahiro Hyodo, Hidehiko Ogata, Naoki Kawamura, Tsuguhiro Nonaka, Masayuki Ishii
  • Patent number: 9570981
    Abstract: A bidirectional DC-DC converter includes a series circuit of a first winding of a first reactor, a second reactor, and a first switch connected to both ends of a first DC power source, a series circuit of a second switch and a second DC power source connected to both ends of the first switch, a series circuit of a second winding of the first reactor, a third reactor, a first selector switch, and a first diode connected to both ends of a series circuit of the second reactor and the first switch, a series circuit of a second selector switch, a second diode, and the second DC power source connected to both ends of a series circuit of the first selector switch and first diode, and a controller turning on/off the switches and the selector switches.
    Type: Grant
    Filed: January 24, 2013
    Date of Patent: February 14, 2017
    Assignees: Sanken Electric Co., Ltd., National University Corporation Shimane University
    Inventors: Hiromitsu Terui, Hideki Asuke, Hideharu Takano, Masayoshi Yamamoto, Takahiro Kawashima
  • Patent number: 9515450
    Abstract: A plurality of cores 51 is disposed around the center axis of a first cladding 52 in a state in which an inter-core distance ? of cores adjacent to each other is equal, a refractive index n1 of the core 51 is provided higher than a refractive index n2 of the first cladding 52, and the refractive index n2 of the first cladding 52 is provided higher than a refractive index n3 of a second cladding 53. Moreover, 5.8??/MFD(2?c/(?c+?op))?8 is satisfied, where the inter-core distance is defined as ?, a mode field diameter of the core is defined as MFD, a cutoff wavelength is defined as ?c, and a wavelength of communication light incident on the core 51 is defined as ?op.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: December 6, 2016
    Assignees: FUJIKURA LTD., NIPPON TELEGRAPH AND TELEPHONE CORPORATION, OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION, NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
    Inventors: Shoichiro Matsuo, Katsuhiro Takenaga, Kentaro Ichii, Hirotaka Ono, Kyouzou Tsujikawa, Makoto Yamada, Hiroji Masuda
  • Patent number: 9266106
    Abstract: A convenient technique allows detecting fluorescence emitted in the channel with a uniformly high detection sensitivity and a good reproducibility. On the front face side of a plate-like body 11, a groove-shaped introduction channel 12 and separation channel 14 are formed. In this micro-channel chip 10, on the inner faces of a groove constituting the separation channel 14 formed in a surface of the plate-like body 11, there is formed a fine particle layer 20 provided by sintering fine particles having an average particle diameter of 10 to 500 nm mainly composed of zinc oxide (ZnO) or titanium oxide (TiO2).
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: February 23, 2016
    Assignee: NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
    Inventors: Yasuhisa Fujita, Haruo Takeshita, Junko Fujihara, Yutaka Fukui, Mari Tabuchi
  • Patent number: 9252556
    Abstract: The first cladding 52 has a two-layer structure formed of a solid inner layer 62A passed through the center axis of the first cladding 52 and an outer layer 62B enclosing the inner layer 62A and the plurality of cores 51 with no gap. A refractive index n1 of the core 51 is provided higher than refractive indexes n2A and n2B of the inner layer 62A and the outer layer 62B, the refractive indexes n2A and n2B of the inner layer 62A and the outer layer 62B are provided higher than a refractive index n3 of the second cladding 53, and the refractive index n2A of the inner layer 62A is provided lower than the refractive index n2B of the outer layer 62B.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: February 2, 2016
    Assignees: FUJIKURA LTD., NIPPON TELEGRAPH AND TELEPHONE CORPORATION, OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION, NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
    Inventors: Shoichiro Matsuo, Katsuhiro Takenaga, Kentaro Ichii, Hirotaka Ono, Kyouzou Tsujikawa, Makoto Yamada, Hiroji Masuda
  • Publication number: 20150318659
    Abstract: A plurality of cores 51 is disposed around the center axis of a first cladding 52 in a state in which an inter-core distance ? of cores adjacent to each other is equal, a refractive index n1 of the core 51 is provided higher than a refractive index n2 of the first cladding 52, and the refractive index n2 of the first cladding 52 is provided higher than a refractive index n3 of a second cladding 53. Moreover, 5.8??/MFD(2?c/(?c+?op))?8 is satisfied, where the inter-core distance is defined as ?, a mode field diameter of the core is defined as MFD, a cutoff wavelength is defined as ?c, and a wavelength of communication light incident on the core 51 is defined as ?op.
    Type: Application
    Filed: October 31, 2013
    Publication date: November 5, 2015
    Applicants: FUJIKURA LTD., NIPPON TELEGRAPH AND TELEPHONE CORPORATION, OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION, NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
    Inventors: Shoichiro Matsuo, Katsuhiro Takenaga, Kentaro Ichii, Hirotaka Ono, Kyouzou Tsujikawa, Makoto Yamada, Hiroji Masuda
  • Publication number: 20150318661
    Abstract: The first cladding 52 has a two-layer structure formed of a solid inner layer 62A passed through the center axis of the first cladding 52 and an outer layer 62B enclosing the inner layer 62A and the plurality of cores 51 with no gap. A refractive index n1 of the core 51 is provided higher than refractive indexes n2A and n2B of the inner layer 62A and the outer layer 62B, the refractive indexes n2A and n2B of the inner layer 62A and the outer layer 62B are provided higher than a refractive index n3 of the second cladding 53, and the refractive index n2A of the inner layer 62A is provided lower than the refractive index n2B of the outer layer 62B.
    Type: Application
    Filed: October 31, 2013
    Publication date: November 5, 2015
    Applicants: FUJIKURA LTD., NIPPON TELEGRAPH AND TELEPHONE CORPORATION, OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION, NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
    Inventors: Shoichiro Matsuo, Katsuhiro Takenaga, Kentaro Ichii, Hirotaka Ono, Kyouzou Tsujikawa, Makoto Yamada, Hiroji Masuda
  • Publication number: 20150070942
    Abstract: A DC-DC converter includes a coupling transformer that has windings 11 and 12, switches (Tr1, Tr2) that are connected through the windings to both ends of a DC power source Vi, a series circuit that is connected to both ends of each of the switches and includes a diode and a smoothing capacitor, and a controller 100 that alternately turns on the switches Tr1 and Tr2 and simultaneously turns on the switches Tr1 and Tr2 for a predetermined overlapping period on every half cycle. The coupling transformer 1 includes an I-shaped core 4, two E-shaped cores 2 and 3 holding the I-shaped core 4 between them, and a gap 5 formed between each of center legs 2a and 3a of the E-shaped cores 2 and 3 and the I-shaped core 4. The windings 11 and 12 are wound around the I-shaped core 4.
    Type: Application
    Filed: January 24, 2013
    Publication date: March 12, 2015
    Applicants: Sanken Electric Co., Ltd., National University Corporation Shimane University
    Inventors: Hiromitsu Terui, Hideki Asuke, Hideharu Takano, Masayoshi Yamamoto, Jun Imaoka