Abstract: A three-dimensional guide for a wire for forming a pedicle screw insertion hole is produced based on a CT image of a spine, and includes a contact surface section that comes in surface contact with a morphological surface of a bone at an insertion site, and a guide block section that is provided upright from the contact surface section. The guide block section has a guide hole that restricts the insertion direction of the wire. The guide hole has an inner diameter slightly larger than the outer diameter of the wire. The guide hole has a length of 15 to 30 mm to restrict the insertion position and the insertion direction of the wire.

Abstract: The dried amniotic membrane is produced by drying a fresh amniotic membrane, which envelopes an embryo of an animal including human, and can be used as a substitute membrane for a membrane tissue in a living body; the dried amniotic membrane is dehydrated and dried so that the dried amniotic membrane can be stored in a dry air in a sterile state; when hydrated again by immersing in water or a buffer solution, the amniotic membrane still has an epithelial cell, a basement membrane and a connective tissue which constitute the fresh amniotic membrane. The dried amniotic membrane is useful as a medical substitute membrane for a membrane tissue in a living body such as a dura mater, a meninx, a pericardium, a pleura and a peritoneum.

Abstract: In a conventional Bagley polygon power divider of a planar configuration, a length of transmission lines from an input port to output ports adjacent thereto on both sides is determined to be a quarter wavelength and a geometry thereof is an odd regular polygon with each side being a length equal to half of a wavelength at a designed frequency, which is large in size. Since the output ports are located at vertices of the regular polygon, inconvenience can be caused, e.g., in arrangement of the output ports. The present invention is directed to a design wherein only a characteristic impedance of a transmission line is designated for achieving matching and wherein a length of the line is allowed to be arbitrarily selected. This permits the line length between adjacent output ports to be appropriately adjusted to a short one according to a design object, and also enables fabrication of a power divider in which output ports are aligned in a line.

Abstract: A method which can isolate plasma cells and plasmablasts efficiently and with high purity, from mammals and birds, without using a cell surface marker is provided. Further disclosed is a fluorescent probe wherein the staining selectivity for the endoplasmic reticulum of cells is higher than the staining selectivity for cell organelles other than the endoplasmic reticulum. Also disclosed is a method for identifying plasma cells and plasmablasts which includes staining cells derived from lymph node tissue or similar by using this probe, and identifying plasma cells and plasmablasts on the basis of the fluorescence intensity from the stained cells. Also disclosed is a fluorescent probe wherein the staining selectivity for cell nuclei is higher than the staining selectivity for cell organelles other than the cell nuclei.

Abstract: Provided is a method for selectively obtaining, for a given target gene, a “joined DNA fragment” wherein just a target gene fragment is joined with desired other DNA fragments, regardless of whether a DNA fragment containing a target gene sequence has been purified. In the provided method, a double-stranded joining DNA fragment containing a sequence A and/or a sequence B is selectively joined to the ends of a target gene fragment. A mixture of a double-stranded gene fragment, the 3? end of which is protruding, and the double-stranded joining DNA fragment, which are related in a prescribed manner, undergoes at least two cycles of thermal denaturation, reassociation, and DNA synthesis, resulting in a “joined DNA fragment,” which is a double-stranded DNA fragment including at least one instance of a sequence resulting from joining sequence A, the target gene sequence, and sequence B. A “single-side joined DNA fragment” can also be obtained, by a similar method.

Abstract: A system rapidly detects and identifies pathogenic bacteria responsible for infection (particularly septicemia), and selects an appropriate antimicrobial drug. A method according to the present invention for detecting and identifying pathogenic bacteria includes performing gene amplification such as real-time PCR, and analyzing the combination of the melting temperatures (Tm values) determined by gene amplification product melting curve analysis or the difference between the Tm values. Specifically, real-time PCR is performed using 4 to 16 primer sets including 1 to 7 primer sets for the 16S ribosomal RNA of bacteria, 1 to 6 primer sets for the 18S ribosomal RNA of fungi, and one primer set respectively for the spa gene and the mecA gene specific to MRSA, and the combination of the Tm values of the amplification product or the combination of the differences between the Tm values is compared with a database to identify pathogenic bacteria responsible for septicemia.

Abstract: A fused tricyclic compound having aldose reductase inhibitory activity and shown by the following formula, wherein R1 represents 1 to 3 atoms or substituents selected from a hydrogen atom, a halogen atom, a substituted or unsubstituted alkyl, cycloalkyl, alkylene, or alkoxy group, and a protected or unprotected hydroxyl or carboxyl group, R2 represents a protected or unprotected carboxyl group, R3 represents 1 or 2 atoms or substituents selected from a hydrogen atom, a halogen atom, an oxo group, a substituted or unsubstituted alkyl or alkoxy group, and a protected or unprotected carboxyl group, A represents an alkylene group, and B represents an oxygen atom, a sulfur atom, or a group shown by the following formula, wherein R4 represents an alkyl or aryl group substituted by an aryl, cycloalkyl, or heterocyclic group, and X represents an oxygen atom or a sulfur atom, provided that, when B represents a group shown by the following formula: wherein R4 represents an alkyl or aryl group substituted

Abstract: An organic transistor includes a semiconductor section that includes a thin-film laminate in which a first organic thin film and a second organic thin film are alternately stacked. The thin-film laminate includes at least two layers of the first organic thin film. The first organic thin film is a pentacene thin film, and the second organic thin film is an amorphous organic thin film. The pentacene thin film may be a pentacene bilayer thin film, and the amorphous organic thin film may be a tetraaryldiamine thin film. The tetraaryldiamine thin film may be an ?-NPD thin film. The organic transistor has improved transistor characteristics (e.g., mobility, ON/OFF ratio, or threshold value control).

Abstract: A digital microphone comprises a ?? modulator. The ?? modulator has a resonator including a membrane which vibrates by receiving a sound wave and a wiring pattern disposed opposite to the membrane, an oscillator, including the resonator, for outputting an FM signal according to the vibration of the membrane, and a one-bit quantizer for outputting a one-bit quantized signal by sampling the FM signal with a high-frequency clock.

Abstract: A tissue piece forming device suitable for forming a tissue piece required in the process of fabricating a novel tissue array chip having many benefits such as the one that the tissue array chip can be fabricated even if the tissue included in a tissue block has a small thickness. The tissue piece forming device (100) for forming a sheet-like tissue piece (S) into a roll shape includes a rotary shaft (1) to which one end of the sliced tissue piece (S) is secured and a drive means for rotating the rotary shaft (1). The tissue piece (S) can be formed into a tight roll shape while rotating the rotary shaft (1).

Abstract: The method for manufacturing an unsaturated hydrocarbon and an oxygen-containing compound according to the present invention comprises: a first step of dispersing a catalyst in poly-?-olefin and reducing the catalyst with carbon monoxide or synthesis gas, wherein the catalyst is prepared by supporting iron on a support containing manganese and having an average pore size of 2 to 100 nm; and a second step of bringing the catalyst after reduction in the first step into contact with synthesis gas under the conditions of a reaction temperature of 100 to 600° C. and a reaction pressure of 0.1 to 10 MPa to obtain a reaction product containing an unsaturated hydrocarbon and an oxygen-containing compound.

Abstract: A device for detecting or quantifying influenza viruses in a sample, which comprises a detection region having a human anti-influenza virus nucleoprotein antibody immobilized onto a support, a sample supply region, and a sample-migrating region; and a kit for detecting or quantifying influenza viruses, which comprises a solid phase in which a human anti-influenza virus nucleoprotein antibody is fixed onto a carrier.

Abstract: Disclosed is a method which can achieve the homologous recombination of a gene of interest selectively. Also disclosed is a recombinant DNA molecule produced by the method. Specifically disclosed is a homologous recombination method which uses a PCR product and a linearized vector. The PCR product comprises a sequence for a target gene and amplification primer sequences P1 and P2 attached to both termini of the sequence for the target gene.

Abstract: Disclosed is organic diode which is capable of light emitting display by an organic EL display, image sensing by a organic photodiode and power generation by an organic solar cell. Also disclosed is a matrix panel of such a multifunction organic diode. Specifically disclosed is a multifunction organic diode comprising a first electrode (12) formed on a substrate (11), an organic thin film (13) formed on the first electrode (12) and having both light emitting and photoconductive properties, and a second electrode (14) formed on the organic thin film (13).

Abstract: The present invention provides a device and a method whereby plural kinds of reaction operations and washing operations can be conducted in parallel without washing or replacing an instrument used in transferring a solution and the like in each operation. A reaction device having a plurality of projecting barriers provided in a line on one surface of a substrate, wherein the projecting barrier has at least one cutoff portion and an inner space capable of holding a droplet, and at least the face holding the droplets of the substrate surface has a contact angle to pure water of from 90 to 150 degrees.

Abstract: [Subject] To provide laser Doppler blood flow measuring method and device which achieve multi-dimensional measurement efficiently at a high degree of accuracy over a wide range with a simple optical system and device. [Solving Means] Laser light from a semiconductor laser 12 is split and formed into sheet lights Ls using a cylindrical lens 22, and the sheet lights Ls are crossed with each other at a predetermined position. A lens system 30 configured to form an image of scattered lights into a linear shape at a linear irradiation site Lx where the sheet lights Ls cross with each other is provided. An optical fiber array 32 having a plurality of optical fibers 34 is provided at an image-forming position of the lens system 30. Avalanche photodiodes 42 configured to convert the scattered lights which are shifted in frequency by the Doppler effect caused by the blood flow into electric signals for the each optical fiber 34 are provided.

Abstract: Provided is a signal analysis device that has a high frequency resolution not depending on an analysis window length and can analyze a frequency with considerably high accuracy. When the signal analysis device inputs therein an analysis object signal to be analyzed, the device obtains a frequency f?, amplitude A? and an initial phase ?? such that the sum of squares of a difference between the analysis object signal and a sinusoidal model signal expressed by a phase using the frequency f? and the initial phase ?? and by the amplitude A? is a minimum value.

Abstract: A fused tricyclic compound having aldose reductase inhibitory activity and shown by the following formula, wherein R1 represents 1 to 3 atoms or substituents selected from a hydrogen atom, a halogen atom, a substituted or unsubstituted alkyl, cycloalkyl, alkylene, or alkoxy group, and a protected or unprotected hydroxyl or carboxyl group, R2 represents a protected or unprotected carboxyl group, R3 represents 1 or 2 atoms or substituents selected from a hydrogen atom, a halogen atom, an oxo group, a substituted or unsubstituted alkyl or alkoxy group, and a protected or unprotected carboxyl group, A represents an alkylene group, and B represents an oxygen atom, a sulfur atom, or a group shown by the following formula, wherein R4 represents an alkyl or aryl group substituted by an aryl, cycloalkyl, or heterocyclic group, and X represents an oxygen atom or a sulfur atom, provided that, when B represents a group shown by the following formula: wherein R4 represents an alkyl or aryl group substituted wi

Abstract: [Task] A process of fabricating a tissue array block; a process of fabricating a tissue array sheet; a tissue array block; a tissue array chip; a system of fabricating a tissue array block; and a system of fabricating a tissue array sheet are proposed, in which the tissue array block can be fabricated even in the case of that having a small thickness, is little affected by tissue hardness and, when having been processed into a tissue array chip, does not suffer any defect in a piece of tissue or at a site of interests, enables the collection of pieces of tissue from a dispersed area, also enables the establishment of positional relationship between the inside of a tissue piece and the inside of a tissue block, and scarcely affects the utilization of the tissue block remaining after collecting the pieces of tissue. [Solving Means] A tissue block B1 is sliced to fabricate roll-shaped pieces of tissue t2. Then, the roll-shaped tissue pieces t2 are inserted into a base block B2 to give a tissue array block B3.

Abstract: In a conventional Bagley polygon power divider of a planar configuration, a length of transmission lines from an input port to output ports adjacent thereto on both sides is determined to be a quarter wavelength and a geometry thereof is an odd regular polygon with each side being a length equal to half of a wavelength at a designed frequency, which is large in size. Since the output ports are located at vertices of the regular polygon, inconvenience can be caused, e.g., in arrangement of the output ports. The present invention is directed to a design wherein only a characteristic impedance of a transmission line is designated for achieving matching and wherein a length of the line is allowed to be arbitrarily selected. This permits the line length between adjacent output ports to be appropriately adjusted to a short one according to a design object, and also enables fabrication of a power divider in which output ports are aligned in a line.