Patents Assigned to NeoMatrix, LLC
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Publication number: 20110118627Abstract: Disclosed is a disposable patient interface for an intraductal fluid aspiration system. The interface has a flexible tubular distal member for contacting the patient, and a proximal support portion forming a vacuum chamber therein. The support portion has a vacuum aperture for communication with a source of vacuum, and a retention structure for releasably mounting within a hand piece of an intraductal fluid aspiration system. The flexible member preferably has a low modulus of elasticity and a high tear strength, such that it can be stretched to fit over a rigid support without rupture.Type: ApplicationFiled: January 26, 2011Publication date: May 19, 2011Applicant: NEOMATRIX, LLCInventors: Kevin B. Morton, Rex O. Bare, Jeffrey C. Smith, Timothy J. Payne, Paul Gleason
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Patent number: 7468043Abstract: Disclosed is a method and apparatus for accomplishing a noninvasive screen for breast disease markers, including breast cancer markers and cytologically abnormal cells. Intraductal fluid is noninvasively aspirated using compression, heating and suction cycles. The removed sample is thereafter assayed for the presence of cytologically abnormal cells and/or one or more breast disease markers. In addition to the diagnostic applications of the disclosed method and apparatus, a therapeutic application is also contemplated wherein intraductal fluids are noninvasively aspirated using compression, heating and suction cycles to remove toxic buildups within the fluid.Type: GrantFiled: April 5, 2005Date of Patent: December 23, 2008Assignee: Neomatrix, LLCInventors: Kevin B. Morton, Rex O. Bare, Jeffrey C. Smith, Timothy J. Payne, Paul Gleason
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Publication number: 20080015495Abstract: Disclosed is a method and apparatus for accomplishing a noninvasive screen for breast disease markers, including breast cancer markers and cytologically abnormal cells. Intraductal fluid is noninvasively aspirated using compression, heating and suction cycles. The removed sample is thereafter assayed for the presence of cytologically abnormal cells and/or one or more breast disease markers. In addition to the diagnostic applications of the disclosed method and apparatus, a therapeutic application is also contemplated wherein intraductal fluids are noninvasively aspirated using compression, heating and suction cycles to remove toxic buildups within the fluid.Type: ApplicationFiled: July 10, 2007Publication date: January 17, 2008Applicant: Neomatrix, LLCInventors: Kevin Morton, Rex Bare, Jeffrey Smith, Timothy Payne, Paul Gleason
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Publication number: 20080015469Abstract: Disclosed is a disposable patient interface for an intraductal fluid aspiration system. The interface has a flexible tubular distal member for contacting the patient, and a proximal support portion forming a vacuum chamber therein. The support portion has a vacuum aperture for communication with a source of vacuum, and a retention structure for releasably mounting within a hand piece of an intraductal fluid aspiration system. The flexible member preferably has a low modulus of elasticity and a high tear strength, such that it can be stretched to fit over a rigid support without rupture.Type: ApplicationFiled: July 10, 2007Publication date: January 17, 2008Applicant: Neomatrix, LLCInventors: Kevin Morton, Rex Bare, Jeffrey Smith, Timothy Payne, Paul Gleason
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Patent number: 6981950Abstract: Disclosed is an apparatus for noninvasive intraductal fluid aspiration. Intraductal fluid is noninvasively aspirated using compression, heating and suction cycles. The device is configured to provide a compression force, deliver heat, and apply a vacuum pressure to encourage the aspiration of patient fluid. The device includes an adjustable support and a movable wall for applying compression. Withdrawn fluid may be used either for diagnostic or therapeutic purposes.Type: GrantFiled: February 8, 2002Date of Patent: January 3, 2006Assignee: Neomatrix, LLCInventors: Kevin B. Morton, Rex O. Bare, Jeffrey C. Smith, Timothy J. Payne, Paul Gleason
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Patent number: 6899696Abstract: A method is disclosed for noninvasively obtaining intraductal fluid. The method includes the use of an intraductal fluid sampling device to contact the patient, provide compression, and deliver heat thereto according to predetermined cycle characteristics. The cycle characteristics, such as compression cycle times and compression rates, may be varied and controlled by a control circuit.Type: GrantFiled: March 29, 2004Date of Patent: May 31, 2005Assignee: Neomatrix, LLCInventors: Kevin B. Morton, Rex O. Bare, Jeffrey C. Smith, Timothy J. Payne, Paul Gleason
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Patent number: 6875184Abstract: Disclosed is a method and apparatus for accomplishing a noninvasive screen for breast disease markers, including breast cancer markers and cytologically abnormal cells. Intraductal fluid is noninvasively aspirated using compression, heating and suction cycles. The removed sample is thereafter assayed for the presence of cytologically abnormal cells and/or one or more breast disease markers. In addition to the diagnostic applications of the disclosed method and apparatus, a therapeutic application is also contemplated wherein intraductal fluids are noninvasively aspirated using compression, heating and suction cycles to remove toxic buildups within the fluid.Type: GrantFiled: February 8, 2002Date of Patent: April 5, 2005Assignee: Neomatrix, LLCInventors: Kevin B. Morton, Rex O. Bare, Jeffrey C. Smith, Timothy J. Payne, Paul Gleason
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Patent number: 6866994Abstract: Disclosed is a method and apparatus for accomplishing a noninvasive screen for breast disease markers, including breast cancer markers and cytologically abnormal cells. Intraductal fluid is noninvasively aspirated using compression, heating and suction cycles. The removed sample is thereafter assayed for the presence of cytologically abnormal cells and/or one or more breast disease markers. Sample size and intraductal mobility of breast disease markers may be enhanced by retrograde introduction of a carrier. Devices and assays are also disclosed.Type: GrantFiled: May 30, 2001Date of Patent: March 15, 2005Assignee: NeoMatrix, LLCInventor: Kevin Morton
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Patent number: 6712785Abstract: A method is disclosed for noninvasively obtaining intraductal fluid. The method includes the use of an intraductal fluid sampling device to contact the patient, provide compression, and deliver heat thereto according to predetermined cycle characteristics. The cycle characteristics, such as compression cycle times and compression rates, may be varied and controlled by a control circuit.Type: GrantFiled: February 8, 2002Date of Patent: March 30, 2004Assignee: Neomatrix, LLCInventors: Kevin B. Morton, Rex O. Bare, Jeffrey C. Smith, Timothy J. Payne, Paul Gleason
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Patent number: 6676610Abstract: Disclosed is a disposable patient interface for an intraductal fluid aspiration system. The interface has a flexible tubular distal member for contacting the patient, and a rigid proximal member forming a vacuum chamber therein. The rigid member has a vacuum aperture for communication with a source of vacuum. The flexible member preferably has a low modulus of elasticity and a high tear strength, such that it can be stretched to fit over a rigid support without rupture.Type: GrantFiled: February 8, 2002Date of Patent: January 13, 2004Assignee: Neomatrix, LLCInventors: Kevin B. Morton, Rex O. Bare, Jeffrey C. Smith, Timothy J. Payne, Paul Gleason
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Patent number: 6517513Abstract: Methods and devices are disclosed for reducing the level of carcinogens in the breast, and influencing the transport of blood carotenoids into the intraductal environment. In one embodiment, the device comprises a pump having compression, suction, and heat adapted to optimize noninvasive extraction of intraductal breast fluid during periods of non-lactation, from a parous or nulliparous patient.Type: GrantFiled: January 21, 2000Date of Patent: February 11, 2003Assignees: NeoMatrix, LLC, Wayne State UniversityInventors: Chandice Covington, Kevin Morton