Patents Assigned to NEOTHETICS, INC.
  • Lipolytic methods
    Patent number: 9707192
    Abstract: Compositions, formulations, methods, and systems for treating regional fat deposits comprise contacting a targeted fat deposit with a composition comprising long acting beta-2 adrenergic receptor agonist and a compound that reduces desensitization of the target tissue to the long acting beta-2 adrenergic receptor agonist, for example, glucocorticosteroids and/or ketotifen. Embodiments of the composition are administered, for example, by injection, and/or transdermally.
    Type: Grant
    Filed: July 10, 2014
    Date of Patent: July 18, 2017
    Assignee: NEOTHETICS, INC.
    Inventor: John Daniel Dobak
  • Selective, lipophilic, and long-acting beta agonist monotherapeutic formulations and methods for the cosmetic treatment of adiposity and contour bulging
    Patent number: 9597531
    Abstract: Provided herein are pharmaceutical and cosmetic formulations and methods for regional adiposity reduction and treatment of body contour defects such as abdominal bulging; comprising an injectable formulation, said formulation comprising: an active ingredient that consists essentially of an adipose tissue-reducing amount of one or more lipophilic long-acting selective beta-2 adrenergic receptor agonists, or salts, solvates, or polymorphs thereof; and one or more subcutaneously acceptable inactive ingredients.
    Type: Grant
    Filed: November 22, 2011
    Date of Patent: March 21, 2017
    Assignee: NEOTHETICS, INC.
    Inventors: John Daniel Dobak, Kenneth Walter Locke
  • Methods for administration and formulations for the treatment of regional adipose tissue
    Patent number: 9452132
    Abstract: Provided herein are pharmaceutical formulations, methods, and systems for treating regional fat deposits and fat-related conditions and indications. Methods comprise administering a pharmaceutical formulation comprising a long-acting beta-2 adrenergic receptor agonist, for example, salmeterol, suitable for subcutaneous administration. Formulations comprise a pharmaceutical formulation that is suitable for subcutaneous injection comprising: (a) a lipophilic long-acting selective beta-2 adrenergic receptor agonist, or a salt thereof; and (b) at least one subcutaneously acceptable inactive ingredient.
    Type: Grant
    Filed: July 29, 2015
    Date of Patent: September 27, 2016
    Assignee: NEOTHETICS, INC.
    Inventors: John Daniel Dobak, Kenneth Walter Locke
  • Lipolytic methods
    Patent number: 9452147
    Abstract: Compositions, formulations, methods, and systems for treating regional fat deposits comprise contacting a targeted fat deposit with a composition comprising long acting beta-2 adrenergic receptor agonist and a compound that reduces desensitization of the target tissue to the long acting beta-2 adrenergic receptor agonist, for example, glucocorticosteroids and/or ketotifen. Embodiments of the composition are administered, for example, by injection, and/or transdermally.
    Type: Grant
    Filed: August 25, 2015
    Date of Patent: September 27, 2016
    Assignee: NEOTHETICS, INC.
    Inventor: John Daniel Dobak
  • Methods of using lipolytic formulations for regional adipose tissue treatment
    Patent number: 9370498
    Abstract: Compositions, formulations, methods, and systems for treating regional fat deposits comprise contacting a targeted fat deposit with a composition comprising long acting beta-2 adrenergic receptor agonist and a compound that reduces desensitization of the target tissue to the long acting beta-2 adrenergic receptor agonist, for example, glucocorticosteroids and/or ketotifen. Embodiments of the composition are administered, for example, by injection, and/or transdermally.
    Type: Grant
    Filed: April 19, 2010
    Date of Patent: June 21, 2016
    Assignee: NEOTHETICS, INC.
    Inventor: John Daniel Dobak
  • Lipolytic methods for regional adiposity comprising salmeterol or formoterol
    Patent number: 9198885
    Abstract: Compositions, formulations, methods, and systems for treating regional fat deposits comprise contacting a targeted fat deposit with a composition comprising long acting beta-2 adrenergic receptor agonist and a compound that reduces desensitization of the target tissue to the long acting beta-2 adrenergic receptor agonist, for example, glucocorticosteroids and/or ketotifen. Embodiments of the composition are administered, for example, by injection, and/or transdermally.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: December 1, 2015
    Assignee: NEOTHETICS, INC.
    Inventor: John Daniel Dobak
  • Methods for administration and formulations for the treatment of regional adipose tissue
    Patent number: 9132084
    Abstract: Provided herein are pharmaceutical formulations, methods, and systems for treating regional fat deposits and fat-related conditions and indications. Methods comprise administering a pharmaceutical formulation consisting essentially of a long-acting beta-2 adrenergic receptor agonist, for example, salmeterol, suitable for subcutaneous administration. Methods further comprise administering a pharmaceutical formulation that is suitable for subcutaneous injection comprising: (a) a lipophilic long-acting selective beta-2 adrenergic receptor agonist and/or glucocorticosteroid, or a salt, optical isomer, racemate, solvate, or polymorph thereof; and (b) at least one subcutaneously acceptable inactive ingredient.
    Type: Grant
    Filed: May 26, 2010
    Date of Patent: September 15, 2015
    Assignee: NEOTHETICS, INC.
    Inventors: John Daniel Dobak, Kenneth Walter Locke