Patents Assigned to Neovasc Tiara Inc.
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Publication number: 20240122705Abstract: A prosthetic cardiac valve comprises an anchor having an atrial skirt, an annular region, and a ventricular skirt. The prosthetic valve also has a plurality of prosthetic valve leaflets each having a first end and a free end. The first end is coupled with the anchor and the free end is opposite the first end. The prosthetic cardiac valve has an open configuration in which the free ends of the prosthetic valve leaflets are disposed away from one another to allow antegrade blood flow therepast, and a closed configuration in which the free ends of the prosthetic valve leaflets engage one another and substantially prevent retrograde blood flow therepast. The anchor has a collapsed configuration for delivery to the heart and an expanded configuration for anchoring the prosthetic cardiac valve to a patient's heart.Type: ApplicationFiled: December 20, 2023Publication date: April 18, 2024Applicants: Neovasc Tiara Inc., Neovasc Inc.Inventors: Matthew Randy Lane, Colin A. Nyuli, Jeremy Brent Ratz, Arshad Quadri
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Patent number: 11931254Abstract: A low-profile prosthetic valve for treating a native valve includes a radially expandable frame having an expanded configuration and a collapsed configuration. The atrial end of the prosthetic valve forms a flared shape that engages an atrial surface of the native valve. The flare shape flares downward toward a ventricle of the native valve when initially expanded followed by inversion of the flared shape to form a tapered shape tapering toward the ventricle and flaring toward the atrium of the native valve when fully expanded. The prosthetic valve also has a plurality of prosthetic valve leaflets that open and close to control fluid flow through the prosthetic valve.Type: GrantFiled: March 14, 2022Date of Patent: March 19, 2024Assignee: Neovasc Tiara Inc.Inventors: Eric Soun-Sang Fung, Karen Tsoek-Ji Wong, Ephraim Ben-Abraham
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Patent number: 11793640Abstract: A sequentially deployed prosthetic cardiac valve includes a self-expanding frame having an atrial skirt, a ventricular skirt, and an annular region disposed therebetween. A first anterior tab is disposed on an anterior portion of the frame. A posterior tab is on a posterior portion of the self-expanding frame. The frame may be designed so that any portion may expand sequentially in any desired order. For example, a portion of the first anterior tab and a portion of the posterior tab may partially self-expand first. Next, the first anterior tab may fully self-expand before the posterior tab fully self-expands. The posterior tab may fully self-expand next followed by the ventricular skirt, or the ventricular skirt may self-expand next followed by full expansion of the posterior tab.Type: GrantFiled: October 21, 2020Date of Patent: October 24, 2023Assignee: Neovasc Tiara Inc.Inventors: Randy Matthew Lane, Colin A. Nyuli, Alexei J. Marko, Krista L. Neale
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Patent number: 11779742Abstract: An introducer sheath includes an elongate shaft having a proximal end, a distal end and a lumen extending therebetween. An actuatable hemostasis valve in a hub is adjacent the proximal end of the elongate shaft and may be used to prevent blood from escaping from the elongate shaft. The introducer sheath may also have a a self-expanding funnel adjacent the distal end of the elongate shaft.Type: GrantFiled: May 20, 2020Date of Patent: October 10, 2023Assignee: Neovasc Tiara Inc.Inventors: Aaron J. Chalekian, Kellen Bodell, Eric Soun-Sang Fung, Karen Tsoek-Ji Wong
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Patent number: 11737872Abstract: A method of delivering a prosthetic valve to a native mitral valve of patient's heart may include providing a radially expandable prosthetic mitral valve which has an upstream atrial portion, a downstream ventricular portion and an annular region therebetween. A constraint is removed from the ventricular portion thereby allowing radial expansion of a ventricular portion. A first anchoring tab on the ventricular portion is radially expanded and an annular region is radially expanded. An atrial skirt on the atrial flange is radially expanded after radial expansion of the ventricular portion.Type: GrantFiled: November 8, 2019Date of Patent: August 29, 2023Assignee: Neovasc Tiara Inc.Inventors: Eric Soun-Sang Fung, Kathleen Hung, Karen Tsoek-Ji Wong, David Andrew Moffatt
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Patent number: 11617650Abstract: A device for loading a prosthesis onto a delivery system includes a first housing having a central bore. One or more actuators on the first housing may be actuated radially inward to selectively compress a discrete portion of the prosthesis disposed in the central bore.Type: GrantFiled: June 16, 2022Date of Patent: April 4, 2023Assignee: Neovasc Tiara Inc.Inventors: Colin A. Nyuli, Randy Matthew Lane
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Patent number: 11602429Abstract: A prosthetic valve may be used to repair a diseased or otherwise damaged heart valve such as the mitral valve. The prosthetic valve may include atraumatic anchor tabs which may be radiopaque or echogenic. A cinching mechanism may also be coupled to the prosthetic valve to control radial expansion of the prosthetic valve. The cinching mechanism may include a wire lasso or a belt. The prosthetic valve may include an expandable frame which has a reduced number of strut connection nodes to allow a lower profile collapsed configuration and tighter crimping. The commissure posts of the prosthetic valve may extend beyond an edge of the ventricular skirt portion of the device.Type: GrantFiled: April 1, 2020Date of Patent: March 14, 2023Assignee: Neovasc Tiara Inc.Inventors: Eric Soun-Sang Fung, Kathleen Hung, Karen Tsoek-Ji Wong, Aaron J. Chalekian, Connor Lucas Haberl, Anson Wai Chung Cheung, Kellen Bodell, Christopher Brodeur
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Patent number: 11497602Abstract: A prosthetic valve comprises a self-expanding frame which includes a self-expanding atrial skirt that forms a flanged region, a self-expanding ventricular skirt, and a first self-expanding tab coupled with the ventricular skirt. A receptacle for receiving a valve leaflet is formed by the area bounded by an outer surface of the atrial skirt, an outer surface of the ventricular skirt, and an inner surface of the first tab. The receptacle has a window for receiving the valve leaflet that is defined by a gap between an edge of the flange and a tip of the first tab. The gap is maximized when the tip of the first tab is unconstrained and a base of the first tab is at least partially constrained. The gap is minimized when the tip of the first tab and its base are unconstrained.Type: GrantFiled: June 12, 2019Date of Patent: November 15, 2022Assignee: Neovasc Tiara Inc.Inventors: Randy Matthew Lane, Colin A. Nyuli, Alexei J. Marko
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Patent number: 11491006Abstract: A prosthetic valve may be formed to direct flow out of the outflow orifice toward a posterior portion of a heart wall. The prosthetic valve includes an expandable frame which may be covered with a cover that is suturelessly attached to the frame. The prosthetic valve may also include an outflow orifice size which is controlled. Methods of using these devices are also disclosed.Type: GrantFiled: April 10, 2020Date of Patent: November 8, 2022Assignee: Neovasc Tiara Inc.Inventors: Shmuel Banai, Kathleen Hung, Aaron J. Chalekian, Karen Tsoek-Ji Wong, Eric Soun-Sang Fung, Connor Lucas Haberl, David Andrew Moffatt
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Patent number: 11464631Abstract: Methods for the rapid retraction of trans-catheter heart valve delivery systems are provided. A rapid retraction trans-catheter heart valve delivery system comprises a catheter based delivery system. The delivery system has internal mechanisms that allow for the controlled deployment of a heart valve prosthesis, as well as mechanisms that allow for quickly closing the catheter once the heart valve prosthesis has been implanted. This rapid retraction ability allows for reduced procedural durations and thus reduced risk to the patient.Type: GrantFiled: February 20, 2020Date of Patent: October 11, 2022Assignee: Neovasc Tiara Inc.Inventors: Ian Fraser Kerr, Karen Tsoek-Ji Wong, Colin Alexander Nyuli, Randy Matthew Lane
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Patent number: 11432924Abstract: A prosthetic cardiac valve comprises an anchor having an atrial skirt, an annular region, and a ventricular skirt. The prosthetic valve also has a plurality of prosthetic valve leaflets each having a first end and a free end. The first end is coupled with the anchor and the free end is opposite the first end. The prosthetic cardiac valve has an open configuration in which the free ends of the prosthetic valve leaflets are disposed away from one another to allow antegrade blood flow therepast, and a closed configuration in which the free ends of the prosthetic valve leaflets engage one another and substantially prevent retrograde blood flow therepast. The anchor has a collapsed configuration for delivery to the heart and an expanded configuration for anchoring the prosthetic cardiac valve to a patient's heart.Type: GrantFiled: October 21, 2019Date of Patent: September 6, 2022Assignees: Neovasc Tiara Inc., Edwards Lifesciences CardiAQ LLCInventors: Randy Matthew Lane, Colin A. Nyuli, Jeremy Brent Ratz, Arshad Quadri
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Patent number: 11419720Abstract: A prosthetic cardiac valve comprises an anchor having an atrial skirt, an annular region, and a ventricular skirt. The prosthetic valve also has a plurality of prosthetic valve leaflets each having a first end and a free end. The first end is coupled with the anchor and the free end is opposite the first end. The prosthetic cardiac valve has an open configuration in which the free ends of the prosthetic valve leaflets are disposed away from one another to allow antegrade blood flow therepast, and a closed configuration in which the free ends of the prosthetic valve leaflets engage one another and substantially prevent retrograde blood flow therepast. The anchor has a collapsed configuration for delivery to the heart and an expanded configuration for anchoring the prosthetic cardiac valve to a patient's heart.Type: GrantFiled: September 3, 2019Date of Patent: August 23, 2022Assignees: Neovasc Tiara Inc., Edwards Lifesciences CardiAQ LLCInventors: Randy Matthew Lane, Colin A. Nyuli, Jeremy Brent Ratz, Arshad Quadri
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Patent number: 11413139Abstract: A sequentially deployed prosthetic cardiac valve includes a self-expanding frame having an atrial skirt, a ventricular skirt, and an annular region disposed therebetween. A first anterior tab is disposed on an anterior portion of the frame. A posterior tab is on a posterior portion of the self-expanding frame. The frame may be designed so that any portion may expand sequentially in any desired order. For example, a portion of the first anterior tab and a portion of the posterior tab may partially self-expand first. Next, the first anterior tab may fully self-expand before the posterior tab fully self-expands. The posterior tab may fully self-expand next followed by the ventricular skirt, or the ventricular skirt may self-expand next followed by full expansion of the posterior tab.Type: GrantFiled: December 9, 2019Date of Patent: August 16, 2022Assignee: Neovasc Tiara Inc.Inventors: Randy Matthew Lane, Colin A. Nyuli, Alexei J. Marko, Krista L. Neale
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Patent number: 11389294Abstract: A device for loading a prosthesis onto a delivery system includes a first housing having a central bore, One or more actuators on the first housing may be actuated radially inward to selectively compress a discrete portion of the prosthesis disposed in the central bore.Type: GrantFiled: February 5, 2021Date of Patent: July 19, 2022Assignee: Neovasc Tiara Inc.Inventors: Colin A. Nyuli, Randy Matthew Lane
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Patent number: 10856984Abstract: A sequentially deployed prosthetic cardiac valve includes a self-expanding frame having an atrial skirt, a ventricular skirt, and an annular region disposed therebetween. A first anterior tab is disposed on an anterior portion of the frame. A posterior tab is on a posterior portion of the self-expanding frame. The frame may be designed so that any portion may expand sequentially in any desired order. For example, a portion of the first anterior tab and a portion of the posterior tab may partially self-expand first. Next, the first anterior tab may fully self-expand before the posterior tab fully self-expands. The posterior tab may fully self-expand next followed by the ventricular skirt, or the ventricular skirt may self-expand next followed by full expansion of the posterior tab.Type: GrantFiled: August 24, 2018Date of Patent: December 8, 2020Assignee: Neovasc Tiara Inc.Inventors: Randy Matthew Lane, Colin A. Nyuli, Alexei J. Marko, Krista L. Neale
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Publication number: 20200146818Abstract: A prosthetic cardiac valve comprises an anchor having an atrial skirt, an annular region, and a ventricular skirt. The prosthetic valve also has a plurality of prosthetic valve leaflets each having a first end and a free end. The first end is coupled with the anchor and the free end is opposite the first end. The prosthetic cardiac valve has an open configuration in which the free ends of the prosthetic valve leaflets are disposed away from one another to allow antegrade blood flow therepast, and a closed configuration in which the free ends of the prosthetic valve leaflets engage one another and substantially prevent retrograde blood flow therepast. The anchor has a collapsed configuration for delivery to the heart and an expanded configuration for anchoring the prosthetic cardiac valve to a patient's heart.Type: ApplicationFiled: October 21, 2019Publication date: May 14, 2020Applicants: Edwards Lifesciences CardiAQ LLC, Neovasc Tiara Inc.Inventors: Randy Matthew Lane, Colin A. Nyuli, Jeremy Brent Ratz, Arshad Quadri
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Patent number: 10631984Abstract: A delivery system includes a delivery catheter with a capsule configured to carry a prosthesis and a steering catheter for steering the delivery catheter. The delivery catheter can be advanced through a patient's vasculature to a target treatment area. The capsule can be opened and the prosthesis can be deployed into the target treatment area. Additionally, a method for delivering a prosthesis to a target treatment area includes advancing a delivery catheter through a patient's vasculature to the target treatment area, steering the delivery catheter toward the target treatment area, opening a capsule on the delivery catheter, and deploying the prosthesis into the target treatment area.Type: GrantFiled: December 15, 2016Date of Patent: April 28, 2020Assignee: Neovasc Tiara Inc.Inventors: Colin A. Nyuli, Randy Matthew Lane, Karen Tsoek-Ji Wong
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Patent number: 10583002Abstract: A prosthetic valve for implanting in a patient's native valve has a self-expanding frame that comprises a first end, a second end opposite the first end, an anterior portion, and a posterior portion. The self-expanding frame has an expanded configuration adapted to engage tissue at a treatment site, and a collapsed configuration adapted to be delivered to the treatment site. The expandable frame also comprises a self-expanding atrial skirt near the second end, a self-expanding ventricular skirt near the first end, a self-expanding annular region disposed between first and second ends, a first self-expanding anterior tab disposed on the anterior portion, and a self-expanding foot coupled to the posterior portion and extending radially outward. The foot has an outer surface for engaging the tissue thereby facilitating anchoring of the prosthetic valve and minimizing or preventing rotation of the prosthetic valve.Type: GrantFiled: March 3, 2014Date of Patent: March 10, 2020Assignee: Neovasc Tiara Inc.Inventors: Randy Matthew Lane, Colin A. Nyuli, Alexei J. Marko, Krista L. Neale
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Patent number: 10537422Abstract: A sequentially deployed prosthetic cardiac valve includes a self-expanding frame having an atrial skirt, a ventricular skirt, and an annular region disposed therebetween. A first anterior tab is disposed on an anterior portion of the frame. A posterior tab is on a posterior portion of the self-expanding frame. The frame may be designed so that any portion may expand sequentially in any desired order. For example, a portion of the first anterior tab and a portion of the posterior tab may partially self-expand first. Next, the first anterior tab may fully self-expand before the posterior tab fully self-expands. The posterior tab may fully self-expand next followed by the ventricular skirt, or the ventricular skirt may self-expand next followed by full expansion of the posterior tab.Type: GrantFiled: June 21, 2017Date of Patent: January 21, 2020Assignee: Neovasc Tiara Inc.Inventors: Randy Matthew Lane, Colin A. Nyuli, Alexei J. Marko, Krista L. Neale
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Patent number: 10449042Abstract: A prosthetic cardiac valve comprises an anchor having an atrial skirt, an annular region, and a ventricular skirt. The prosthetic valve also has a plurality of prosthetic valve leaflets each having a first end and a free end. The first end is coupled with the anchor and the free end is opposite the first end. The prosthetic cardiac valve has an open configuration in which the free ends of the prosthetic valve leaflets are disposed away from one another to allow antegrade blood flow therepast, and a closed configuration in which the free ends of the prosthetic valve leaflets engage one another and substantially prevent retrograde blood flow therepast. The anchor has a collapsed configuration for delivery to the heart and an expanded configuration for anchoring the prosthetic cardiac valve to a patient's heart.Type: GrantFiled: August 22, 2017Date of Patent: October 22, 2019Assignee: Neovasc Tiara Inc.Inventors: Randy Matthew Lane, Colin A. Nyuli, Jeremy Brent Ratz, Arshad Quadri