Patents Assigned to Neurofluidics, Inc.
  • Publication number: 20210386981
    Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a catheter flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.
    Type: Application
    Filed: June 22, 2021
    Publication date: December 16, 2021
    Applicant: NEUROFLUIDICS, INC.
    Inventors: SHIVANAND LAD, WILLIAM C. MOBLEY, KAROLY NIKOLICH, THOMAS SAUL
  • Publication number: 20210386982
    Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a catheter flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.
    Type: Application
    Filed: June 22, 2021
    Publication date: December 16, 2021
    Applicant: NEUROFLUIDICS, INC.
    Inventors: SHIVANAND LAD, WILLIAM C. MOBLEY, KAROLY NIKOLICH, THOMAS SAUL
  • Patent number: 11065425
    Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a catheter flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: July 20, 2021
    Assignee: Neurofluidics, Inc.
    Inventors: Shivanand Lad, William C. Mobley, Karoly Nikolich, Thomas Saul
  • Patent number: 11040179
    Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a catheter flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: June 22, 2021
    Assignee: Neurofluidics, Inc.
    Inventors: Shivanand Lad, William C. Mobley, Karoly Nikolich, Thomas Saul
  • Publication number: 20200046954
    Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a catheter flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.
    Type: Application
    Filed: August 22, 2019
    Publication date: February 13, 2020
    Applicant: NEUROFLUIDICS, INC.
    Inventors: SHIVANAND LAD, WILLIAM C. MOBLEY, KAROLY NIKOLICH, THOMAS SAUL
  • Patent number: 10398884
    Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a catheter flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: September 3, 2019
    Assignee: NEUROFLUIDICS, INC.
    Inventors: Shivanand Lad, William C. Mobley, Karoly Nikolich, Thomas Saul
  • Patent number: 9895518
    Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a multilumen flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: February 20, 2018
    Assignee: NEUROFLUIDICS, INC.
    Inventors: Shivanand Lad, William C. Mobley, Karoly Nikolich, Thomas Saul
  • Publication number: 20140066830
    Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a multilumen flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.
    Type: Application
    Filed: March 13, 2013
    Publication date: March 6, 2014
    Applicant: Neurofluidics, Inc.
    Inventors: Shivanand Lad, William C. Mobley, Karoly Nikolich, Thomas Saul
  • Patent number: 8435204
    Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. A multilumen flow path allows exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.
    Type: Grant
    Filed: October 9, 2007
    Date of Patent: May 7, 2013
    Assignee: Neurofluidics, Inc.
    Inventors: Shivanand Lad, William C. Mobley, Karoly Nikolich, Thomas Saul