Patents Assigned to Neurofluidics, Inc.
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Publication number: 20210386981Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a catheter flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.Type: ApplicationFiled: June 22, 2021Publication date: December 16, 2021Applicant: NEUROFLUIDICS, INC.Inventors: SHIVANAND LAD, WILLIAM C. MOBLEY, KAROLY NIKOLICH, THOMAS SAUL
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Publication number: 20210386982Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a catheter flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.Type: ApplicationFiled: June 22, 2021Publication date: December 16, 2021Applicant: NEUROFLUIDICS, INC.Inventors: SHIVANAND LAD, WILLIAM C. MOBLEY, KAROLY NIKOLICH, THOMAS SAUL
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Patent number: 11065425Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a catheter flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.Type: GrantFiled: August 22, 2019Date of Patent: July 20, 2021Assignee: Neurofluidics, Inc.Inventors: Shivanand Lad, William C. Mobley, Karoly Nikolich, Thomas Saul
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Patent number: 11040179Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a catheter flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.Type: GrantFiled: August 22, 2019Date of Patent: June 22, 2021Assignee: Neurofluidics, Inc.Inventors: Shivanand Lad, William C. Mobley, Karoly Nikolich, Thomas Saul
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Publication number: 20200046954Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a catheter flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.Type: ApplicationFiled: August 22, 2019Publication date: February 13, 2020Applicant: NEUROFLUIDICS, INC.Inventors: SHIVANAND LAD, WILLIAM C. MOBLEY, KAROLY NIKOLICH, THOMAS SAUL
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Patent number: 10398884Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a catheter flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.Type: GrantFiled: January 19, 2017Date of Patent: September 3, 2019Assignee: NEUROFLUIDICS, INC.Inventors: Shivanand Lad, William C. Mobley, Karoly Nikolich, Thomas Saul
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Patent number: 9895518Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a multilumen flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.Type: GrantFiled: March 13, 2013Date of Patent: February 20, 2018Assignee: NEUROFLUIDICS, INC.Inventors: Shivanand Lad, William C. Mobley, Karoly Nikolich, Thomas Saul
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Publication number: 20140066830Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a multilumen flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.Type: ApplicationFiled: March 13, 2013Publication date: March 6, 2014Applicant: Neurofluidics, Inc.Inventors: Shivanand Lad, William C. Mobley, Karoly Nikolich, Thomas Saul
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Patent number: 8435204Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. A multilumen flow path allows exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.Type: GrantFiled: October 9, 2007Date of Patent: May 7, 2013Assignee: Neurofluidics, Inc.Inventors: Shivanand Lad, William C. Mobley, Karoly Nikolich, Thomas Saul