Patents Assigned to New Chapter, Inc.
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Publication number: 20140271924Abstract: Compositions and methods for modulating blood sugar are provided. The composition comprises gymnema, green coffee, grape seed, hibiscus, cinnamon, holy basil, Russian tarragon, ginger, turmeric, and chromium.Type: ApplicationFiled: March 14, 2014Publication date: September 18, 2014Applicant: New Chapter, Inc.Inventors: Taryn Louise FORRELLI, Paul SCHULICK
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Patent number: 8252345Abstract: The inventive subject matter relates to methods for modulating an eicosanoid metabolic process in cells of an animal in need thereof, which comprises administering to the animal an amount of the inventive compositions effective for regulating the activity of an eicosanoid oxygenase. In particular, the inventive subject matter relates to methods for modulating arachidonic acid metabolism by administering an amount of the inventive compositions effective for regulating the activity of lipoxygenases and cyclooxygenases.Type: GrantFiled: December 29, 2008Date of Patent: August 28, 2012Assignee: New Chapter Inc.Inventors: Thomas Newmark, Paul Schulick, Robert Newman, Bharat Aggarwal
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Patent number: 8114446Abstract: The inventive subject matter relates to methods for modulating an eicosanoid metabolic process in cells of an animal in need thereof, which comprises administering to the animal an amount of the inventive compositions effective for regulating the activity of an eicosanoid oxygenase. In particular, the inventive subject matter relates to methods for modulating arachadonic acid metabolism by administering an amount of the inventive compositions effective for regulating the activity of lipoxygenases and cyclooxygenases.Type: GrantFiled: June 29, 2010Date of Patent: February 14, 2012Assignees: New Chapter Inc., Board Of Regents Of The University Of Texas SystemInventors: Thomas Newmark, Paul Schulick, Robert Newman, Bharat Aggarwal
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Publication number: 20110200689Abstract: The inventive subject matter relates to methods for treating glioblastoma, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry. The inventive subject matter further relates to methods for modulating gene expression of genes selected from the group consisting of interleukin-1?, interleukin-1?, heme oxygenase 1, aldo-keto reductase family 1, member C2, colony stimulating factor 3, leukemia inhibitory factor, heat shock 70 kDa protein, and combinations thereof, by administration of an effective amount of said compositions.Type: ApplicationFiled: March 24, 2011Publication date: August 18, 2011Applicants: NEW CHAPTER INC., THE CLEVELAND CLINIC FOUNDATIONInventors: Thomas NEWMARK, Mladen GOLUBIC, Paul SCHULICK
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Publication number: 20110189220Abstract: The present subject matter relates to a novel mushroom composition and methods for making and using the same. In one aspect, the subject matter involves a composition comprising a combination of mushrooms or components derived from mushrooms selected from the group consisting of Reishi Ganoderma lucidum, Reishi Ganoderma lucidum, Cordyceps sinensis, Maitake Grifola frondosa, Shiitake Lentinula edodes, Poria cocos, Lion's Mane Hericium erinaceus, Mesima Phellinus linteus, Turkey Tail Coriolus Tramentes versicolor, Chaga Inonotus obliquus, and Chaga Inonotus obliquus. In some embodiments, the present subject matter relates to methods for modulating immune function, regulating the activity of lipoxygenases and cyclooxygenases, improving cardiovascular health, and/or inhibiting cell proliferation diseases and disorders. In one embodiment the composition provides a balancing of anti-inflammatory and pro-inflammatory function in an animal, including in humans.Type: ApplicationFiled: January 28, 2011Publication date: August 4, 2011Applicants: NEW CHAPTER INC., BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMInventors: Peiying YANG, Robert NEWMAN, Paul SCHULICK
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Patent number: 7931922Abstract: The inventive subject matter relates to methods for treating glioblastoma, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry. The inventive subject matter further relates to methods for modulating gene expression of genes selected from the group consisting of interleukin-1?, interleukin-1?, heme oxygenase 1, aldo-keto reductase family 1, member C2, colony stimulating factor 3, leukemia inhibitory factor, heat shock 70 kDa protein, and combinations thereof, by administration of an effective amount of said compositions.Type: GrantFiled: November 20, 2009Date of Patent: April 26, 2011Assignees: New Chapter Inc., The Cleveland Clinic FoundationInventors: Thomas Newmark, Mladen Golubic, Paul Schulick
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Publication number: 20110020479Abstract: The inventive subject matter relates to methods for modulating an eicosanoid metabolic process in cells of an animal in need thereof, which comprises administering to the animal an amount of the inventive compositions effective for regulating the activity of an eicosanoid oxygenase. In particular, the inventive subject matter relates to methods for modulating arachadonic acid metabolism by administering an amount of the inventive compositions effective for regulating the activity of lipoxygenases and cyclooxygenases.Type: ApplicationFiled: June 29, 2010Publication date: January 27, 2011Applicants: NEW CHAPTER INC., BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMInventors: Thomas NEWMARK, Paul SCHULICK, Robert NEWMAN, Bharat AGGARWAL
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Publication number: 20110008457Abstract: The present subject matter relates to a novel herbal and oil composition and methods for modulating fatty acid composition and metabolism in an animal. In one aspect, the subject matter involves a composition comprising rosemary extract, oregano extract, and a polyunsaturated oil. In a particular embodiment, the polyunsaturated oil is fish oil or a derivative thereof. In some embodiments, the present subject matter relates to methods for modulating essential dietary fatty acid composition of lipoprotein particles or cell membranes, modulating essential fatty acid metabolism, regulating the activity of lipoxygenases and cyclooxygenases, improving cardiovascular health, and/or inhibiting cell proliferation diseases and disorders.Type: ApplicationFiled: May 28, 2010Publication date: January 13, 2011Applicants: NEW CHAPTER INC., BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMInventors: Robert A. NEWMAN, Peiying YANG, Paul SCHULICK
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Publication number: 20100278947Abstract: The inventive subject matter relates to methods for modulating an eicosanoid metabolic process in cells of an animal in need thereof, which comprises administering to the animal an amount of the inventive compositions effective for regulating the activity of an eicosanoid oxygenase. In particular, the inventive subject matter relates to methods for modulating arachadonic acid metabolism by administering an amount of the inventive compositions effective for regulating the activity of lipoxygenases and cyclooxygenases.Type: ApplicationFiled: December 29, 2008Publication date: November 4, 2010Applicants: New Chapter Inc., The University of Texas MD Anderson Cancer CenterInventors: Thomas Newmark, Paul Schulick, Robert Newman, Bharat Aggarwal
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Patent number: 7744934Abstract: The inventive subject matter relates to methods for treating prostate cancer, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry.Type: GrantFiled: December 29, 2008Date of Patent: June 29, 2010Assignees: New Chapter Inc., Board of Regents of the University of Texas SystemInventors: Thomas Newmark, Paul Schulick, Aaron Katz
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Patent number: 7744931Abstract: The inventive subject matter relates to methods for treating oral cancers, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry. The inventive subject matter further relates to methods for modulating gene expression of genes selected from the group consisting of interleukin-1?, interleukin-1?, heme oxygenase 1, aldo-keto reductase family 1, member C2, colony stimulating factor 3, leukemia inhibitory factor, heat shock 70 kDa protein, and combinations thereof, by administration of an effective amount of said compositions.Type: GrantFiled: November 8, 2007Date of Patent: June 29, 2010Assignees: New Chapter Inc., Board of Regents of the University of Texas SystemInventors: Thomas Newmark, Robert Newman, Peiying Yang, Paul Schulick
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Publication number: 20100074977Abstract: The inventive subject matter relates to methods for treating glioblastoma, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry. The inventive subject matter further relates to methods for modulating gene expression of genes selected from the group consisting of interleukin-1?, interleukin-1?, heme oxygenase 1, aldo-keto reductase family 1, member C2, colony stimulating factor 3, leukemia inhibitory factor, heat shock 70 kDa protein, and combinations thereof, by administration of an effective amount of said compositions.Type: ApplicationFiled: November 20, 2009Publication date: March 25, 2010Applicants: NEW CHAPTER, INC., The Cleveland Clinic FoundationInventors: Thomas Newmark, Mladen Golubic, Paul Schulick
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Publication number: 20100040732Abstract: Nutritional products are prepared using a dual fermentation process in which distinct and separate botanical fermentation and probiotic fermentation steps increase nutritional value and/or quality of a vitamin or other nutritionally relevant compound. Alternatively, both fermentation steps could also be combined. Most preferably, a nutritionally desirable carrier such as cow milk, soy milk, or rice milk is used as fermentation medium, which is then subjected to a botanical fermentation with a sprout extract and a probiotic fermentation with a lactobacillus culture. It is further preferred that at least one of the fermentation steps is performed in the presence of the vitamin or other nutritionally relevant compound.Type: ApplicationFiled: August 18, 2008Publication date: February 18, 2010Applicants: VDF FUTURECEUTICALS, INC., NEW CHAPTER, INC.Inventors: Jeff Van Drunen, John Hunter
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Patent number: 7622142Abstract: The inventive subject matter relates to methods for treating glioblastoma, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry. The inventive subject matter further relates to methods for modulating gene expression of genes selected from the group consisting of interleukin-1?, interleukin-1?, heme oxygenase 1, aldo-keto reductase family 1, member C2, colony stimulating factor 3, leukemia inhibitory factor, heat shock 70 kDa protein, and combinations thereof, by administration of an effective amount of said compositions.Type: GrantFiled: September 14, 2005Date of Patent: November 24, 2009Assignees: New Chapter Inc., The Cleveland Clinic FoundationInventors: Thomas Newmark, Mladen Golubic, Paul Schulick
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Patent number: 7563462Abstract: The inventive subject matter relates to methods for modulating an eicosanoid metabolic process in cells of an animal in need thereof, which comprises administering to the animal an amount of the inventive compositions effective for regulating the activity of an eicosanoid oxygenase. In particular, the inventive subject matter relates to methods for modulating arachadonic acid metabolism by administering an amount of the inventive compositions effective for regulating the activity of lipoxygenases and cyclooxygenases.Type: GrantFiled: June 14, 2006Date of Patent: July 21, 2009Assignees: The University of Texas MD Anderson Cancer Center, New Chapter Inc.Inventors: Thomas Newmark, Paul Schulick, Robert Newman, Bharat Aggarwal
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Publication number: 20090110757Abstract: The inventive subject matter relates to methods for treating prostate cancer, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry.Type: ApplicationFiled: December 29, 2008Publication date: April 30, 2009Applicant: New Chapter Inc.Inventors: Thomas Newmark, Paul Schulick, Aaron Katz
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Patent number: 7470440Abstract: The inventive subject matter relates to methods for treating prostate cancer, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry.Type: GrantFiled: June 26, 2006Date of Patent: December 30, 2008Assignee: New Chapter, Inc.Inventors: Thomas Newmark, Paul Schulick, Aaron Katz
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Patent number: 7070816Abstract: The inventive subject matter relates to methods for treating prostatic intraepithelial neoplasia, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry.Type: GrantFiled: December 5, 2003Date of Patent: July 4, 2006Assignee: New Chapter, Inc.Inventors: Thomas Newmark, Paul Schulick, Aaron Katz
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Patent number: 7067159Abstract: The inventive subject matter relates to methods for treating prostate cancer, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry.Type: GrantFiled: December 5, 2003Date of Patent: June 27, 2006Assignee: New Chapter, Inc.Inventors: Thomas Newmark, Paul Schulick, Aaron Katz
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Patent number: D778729Type: GrantFiled: October 9, 2014Date of Patent: February 14, 2017Assignee: New Chapter, Inc.Inventor: Todd Spenceman