Abstract: The method involves an approach of inhibiting replication of dysfunctional cells which adopt alternative lengthening of telomeres, or “ALT.” The methodology involves inhibition of Fanconi anemia complementation group M (FANCM), and one or both of breast cancer 1 (BRCA1) and Bloom syndrome protein (BLM). These molecules are the keys to the elimination of replication stress caused by ALT. In other words, they permit the dysfunctional cells to proliferate. Inhibition of these molecules inhibits proliferation.

Abstract: The invention relates to a catheter useful in recording His electrogram alternans. The catheter includes a catheter probe containing at least one row of receiving poles positioned at an edge of the catheter probe, equidistantly spaced from each other.

Abstract: A motorized walker is provided that can enable users to walk without being slowed by the walker and without needing to exert themselves to push the walker forward. The motorized walker provides additional haptic speed cues to inform the user's posture and locomotion control to prevent falling.

Abstract: A motorized walker is provided that can enable users to walk without being slowed by the walker and without needing to exert themselves to push the walker forward. The motorized walker provides additional haptic speed cues to inform the user's posture and locomotion control to prevent falling.

Abstract: The invention relates to an apparatus, e.g., a bracket, configured for reception of vessels, such as plastic bottles which have been cut in a way which makes them useful upon assembly, as roofing construction elements. The roofing elements, the roofing structures which result and kits for manufacturing these structures, are all features of the invention.

Abstract: The invention relates to an apparatus, e.g., a bracket, configured for reception of vessels, such as plastic bottles which have been cut in a way which makes them useful upon assembly, as roofing construction elements. The roofing elements, the roofing structures which result and kits for manufacturing these structures, are all features of the invention.

Abstract: Various methodologies for the immobilization of molecules such, as multistranded nucleic acid molecules, are described. The methodologies include activation of solid supports, as well as treatment of, e.g. termini of nucleic acid molecules to render them more receptive to immobilization on surfaces.

Abstract: A method for distributing energy in a vehicle having a hybrid electric drive system that includes an internal combustion engine and at least one electric motor which deliver torque to a primary drive shift having at least two drive wheels operatively associated therewith. The method includes the steps of delivering torque from the internal combustion engine and the electric motor to the primary drive shaft to accelerate the vehicle from a stationary position to a predetermined cruising velocity, disengaging the electric motor from the primary drive shaft once the vehicle has accelerate to the cruising velocity to reduce parasitic drag on the system, and delivering torque from the internal combustion engine to the primary drive shaft utilizing the mean horsepower of the internal combustion engine to maintain the vehicle at the cruising velocity.

Abstract: A hybrid electric drive system for a vehicle having at least two drive wheels which receive torque from a primary drive shaft. The system includes an internal combustion engine which is operatively connected to a secondary drive shaft for delivering torque thereto, a transmission assembly for delivering torque to the primary drive shaft which has an input shaft that is operatively connected to the secondary drive shaft for receiving torque therefrom, and at least one electric motor which is operatively connected to the input shaft of the transmission assembly for delivering torque thereto.

Abstract: An ultrasonic inspection system uses a submerged ultrasonic transducer to provide an ultrasonic beam focused to a small spot on a submerged surface of a member to be internally inspected. By use of a focused beam projected through a fluid, such as water, to a submerged surface, the ultrasonic energy is efficiently coupled to a surface area which may be small and/or of irregular or curved shape. Systems and methods for inspecting turbine rotor blade tenons permit a turbine rotor with hundreds of blades to be rotated past a submerged transducer with automatic recording and processing of ultrasonic echoes to develop two-dimensional color images of internal portions of tenons at which cracks may typically occur. Automated adjustment of beam focusing of a transducer including an array of elements and threshold monitoring of fault-indicative echo returns are provided for.

Abstract: A method and apparatus is disclosed for combining a first video signal representative of a first image and a second video signal representative of a second image. In one embodiment, the first video signal is filtered to remove high frequency two-dimensional diagonal frequency components therefrom. The second video signal is also filtered to remove high frequency two-dimensional diagonal frequency components therefrom. The filtered second video signal is two-dimensionally modulated, and the filtered first video signal is combined with said modulated filtered second video signal. In a further embodiment, filtered signals are spatially decimated and combined.

Abstract: A method and an apparatus are disclosed for encoding and decoding video to achieve bandwidth compression. In one embodiment, frames of a video signal are divided into a multiplicity of tiles. The picture content of each tile is separated into a plurality of frequency bands having a predetermined priority order. Motion is determined at each tile from changes in picture content of the tile from frame to frame. Signals are generated for each frame, the signals including an indication of the motion status for each tile and a representation of a frequency band for each tile. The frequency band representation for each particular tile is selected as a function of the motion status for the particular tile.

Abstract: A method for generating electronic representations of animated images from stored image data elements with reduced computational requirements. The image data elements may be made available from one or more data base sources, and may be of any suitable form from which images can be computed. A first sequence of relatively low resolution frames are computed from the stored image data elements, this first sequence of frames representing animated images over a given time period. A second sequence of relatively high resolution frames are computed from the stored image data elements, this second sequence of frames representing the animated images over the given time period. The number of frames in the second sequence is less than the number of frames in the first sequence. Corresponding frames of the first and second sequences are combined to obtain output high resolution frames representative of the animated images over the given time period.

Abstract: The disclosed invention takes advantage of the fact that the speech information and processing needed for successful animation lip-synching is actually much less than the information and processing which is needed for identifying individual words, as in the traditional speech recognition task, The disclosed embodiment utilizes linear prediction to obtain speech parameters which can be used to identify phonemes from a limited set corresponding to visually distinctive mouth positions. In the disclosed embodiment there is set forth an apparatus for producing lip-synching for a spoken sound track. Means are provided for storing, for each of a number of mouth positions, an unvoiced phonetic information representation associated with a mouth position. Means, responsive to samples of sound from the sound track, are provided for generating unvoiced phonetic information signals for the samples.

Abstract: A solid state light modulator apparatus is disclosed for displaying images represented by video signals. The system includes an array of semiconductor devices having electrodes which extend over the tops of their respective devices. The devices are used, in conjuction with related circuitry, for applying sampled video signals to the electrodes. The resulting charge pattern deforms a conductive/reflective layer, and the deformations are converted to a viewable image by an optical system. The electrodes are divided into separate fingers which decreases the effective grating line spacing of the light modulator and accordingly increases resolution. Electrodes of the array have at least three electrically connected fingers such that at least one of the fingers is interleaved with fingers of an electrode in a row above in said array and at least another of said fingers is interleaved with fingers of an electrode in a row below in said array.

Abstract: A solid state light modulator apparatus for displaying images represented by video signals. The system includes an array of semiconductor devices having electrodes which extend over the tops of their respective devices. The devices are used, in conjunction with related circuitry, for applying sampled video signals to the electrodes. The resulting charge pattern deforms a concuctive/reflective layer, and the deformations are converted to a viewable image by an optical system. The electrodes are divided into separated fingers which decreases the effective grating line spacing of the light modulator and accordingly increases resolution. Also, the electrodes are at two different levels, and the spurious light immunity of the light modulator is improved.

Abstract: A system and method are disclosed for transmission and reception of high definition television signals. A standard television signal is transmitted over a first transmission frequency channel, and an enhancement signal, to be used for enhancing the standard signal to obtain a high definition signal, is transmitted over a second transmission frequency channel that is non-adjacent to the first transmission frequency channel. A code signal, which identifies the second transmission frequency channel, is combined into the standard television signal before transmission. The code signal is recovered at the receiver, and used to automatically tune the receiver to also receive the enhancement signal sent over the second transmission frequency channel. A second code signal, representative of other information, such as the portion of the second transmission frequency channel that contains the enhancement information, can also be sent with the standard signal.

Abstract: An apparatus is disclosed for temporally processing video signals. A temporal filter is used which enhances temporal response of video at around the peak of the human vision transient system's temporal response (which is around 10 Hertz), and results in moving images which appear sharper.

Abstract: A technique is disclosed for generating a progressively scanned video signal from an interlaced signal without the need for motion-adaptive processing. Low resolution information is obtained from the current interlaced field, and the remaining detail information is obtained from a stored signal that includes a prior field or fields. The obtained signal can then be displayed with progressive scanning at full resolution and without motion artifacts.

Abstract: An analog video frame store, resident in certain types of video displays, is used to obtain video signal noise reduction. A frame storage system has an array of semiconductor-controlled storage units for receiving and storing frames of video information as a pattern of stored charge. A circuit is provided for applying sampled portions of the video signals to respective ones of the elemental storage units of the frame storage system. The circuit is operative to apply the sampled portions of the video signals to their respective semiconductor unit storage regions with a time constant for each particular storage unit that depends upon the difference between the sampled signal level being applied to the particular storage unit and the signal level stored at the particular storage unit.