Patents Assigned to NextBio
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Patent number: 10275711Abstract: The present invention relates to methods, systems and apparatus for capturing, integrating, organizing, navigating and querying large-scale data from high-throughput biological and chemical assay platforms. It provides a highly efficient meta-analysis infrastructure for performing research queries across a large number of studies and experiments from different biological and chemical assays, data types and organisms, as well as systems to build and add to such an infrastructure.Type: GrantFiled: August 17, 2012Date of Patent: April 30, 2019Assignee: NextbioInventors: Ilya Kupershmidt, Qiaojuan Jane Su, Francois Andry
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Patent number: 10127353Abstract: According to various embodiments, aspects of the invention provide a highly efficient meta-analysis infrastructure for performing research queries across a large number of studies and experiments from diverse sequencing technologies as well as different biological and chemical assays, data types and organisms, as well as systems to build and add to such an infrastructure. The methods, systems and apparatuses described enable combining orthogonal types of data and available public knowledge to elucidate mechanisms governing normal development, disease progression, as well as susceptibility of individuals to disease or response to drug treatments.Type: GrantFiled: March 6, 2017Date of Patent: November 13, 2018Assignee: NextbioInventors: Ilya Kupershmidt, Qiaojuan Jane Su
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Patent number: 9633166Abstract: According to various embodiments, aspects of the invention provide a highly efficient meta-analysis infrastructure for performing research queries across a large number of studies and experiments from diverse sequencing technologies as well as different biological and chemical assays, data types and organisms, as well as systems to build and add to such an infrastructure. The methods, systems and apparatuses described enable combining orthogonal types of data and available public knowledge to elucidate mechanisms governing normal development, disease progression, as well as susceptibility of individuals to disease or response to drug treatments.Type: GrantFiled: September 21, 2015Date of Patent: April 25, 2017Assignee: NextBioInventors: Ilya Kupershmidt, Qiaojuan Jane Su
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Patent number: 9183349Abstract: According to various embodiments, aspects of the invention provide a highly efficient meta-analysis infrastructure for performing research queries across a large number of studies and experiments from diverse sequencing technologies as well as different biological and chemical assays, data types and organisms, as well as systems to build and add to such an infrastructure. The methods, systems and apparatuses described enable combining orthogonal types of data and available public knowledge to elucidate mechanisms governing normal development, disease progression, as well as susceptibility of individuals to disease or response to drug treatments.Type: GrantFiled: June 8, 2010Date of Patent: November 10, 2015Assignee: NextBioInventors: Ilya Kupershmidt, Qiaojuan Jane Su
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Patent number: 9141913Abstract: The present invention relates to methods, systems and apparatus for capturing, integrating, organizing, navigating and querying large-scale data from high-throughput biological and chemical assay platforms. It provides a highly efficient meta-analysis infrastructure for performing research queries across a large number of studies and experiments from different biological and chemical assays, data types and organisms, as well as systems to build and add to such an infrastructure. According to various embodiments, methods, systems and interfaces for associating experimental data, features and groups of data related by structure and/or function with chemical, medical and/or biological terms in an ontology or taxonomy are provided. According to various embodiments, methods, systems and interfaces for filtering data by data source information are provided, allowing dynamic navigation through large amounts of data to find the most relevant results for a particular query.Type: GrantFiled: March 4, 2009Date of Patent: September 22, 2015Assignee: NextBioInventors: Ilya Kupershmidt, Qiaojuan Jane Su, Qingdi Liu, Satnam Alag, Suman Sundaresh
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Publication number: 20150193576Abstract: According to various embodiments, aspects of the invention provide a highly efficient meta-analysis infrastructure for performing research queries across a large number of studies and experiments from diverse sequencing technologies as well as different biological and chemical assays, data types and organisms, as well as systems to build and add to such an infrastructure. The methods, systems and apparatuses described enable combining orthogonal types of data and available public knowledge to elucidate mechanisms governing normal development, disease progression, as well as susceptibility of individuals to disease or response to drug treatments.Type: ApplicationFiled: June 8, 2010Publication date: July 9, 2015Applicant: NextBioInventors: Ilya Kupershmidt, Qiaojuan Jane Su
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Publication number: 20130166599Abstract: The present invention relates to methods, systems and apparatus for capturing, integrating, organizing, navigating and querying large-scale data from high-throughput biological and chemical assay platforms. It provides a highly efficient meta-analysis infrastructure for performing research queries across a large number of studies and experiments from different biological and chemical assays, data types and organisms, as well as systems to build and add to such an infrastructure.Type: ApplicationFiled: August 17, 2012Publication date: June 27, 2013Applicant: NEXTBIOInventors: Ilya Kupershmidt, Qiaojuan Jane Su, Francois Andry
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Publication number: 20130166320Abstract: Provided herein are methods, systems and apparatus for querying and interpreting data derived from individual patients. The methods, systems and apparatus described herein can be used in clinical and research settings. Included are methods, systems and apparatus for identifying similar patients, germline DNA analysis, somatic tissue analysis, pathway-based therapy selection, prioritizing drugs, and querying a database to return patients and clinical attributes.Type: ApplicationFiled: September 17, 2012Publication date: June 27, 2013Applicant: NEXTBIOInventors: Ilya Kupershmidt, Qiaojuan Jane Su
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Patent number: 8364665Abstract: The present invention relates to methods, systems and apparatus for capturing, integrating, organizing, navigating and querying large-scale data from high-throughput biological and chemical assay platforms. It provides a highly efficient meta-analysis infrastructure for performing research queries across a large number of studies and experiments from different biological and chemical assays, data types and organisms, as well as systems to build and add to such an infrastructure. In particular, aspects of the invention relate to integrating, organizing, navigating and querying “directional” data, such as gene expression profiles.Type: GrantFiled: September 19, 2008Date of Patent: January 29, 2013Assignee: NextBioInventors: Qiaojuan Jane Su, Ilya Kupershmidt
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Patent number: 8275737Abstract: The present invention relates to methods, systems and apparatus for capturing, integrating, organizing, navigating and querying large-scale data from high-throughput biological and chemical assay platforms. It provides a highly efficient meta-analysis infrastructure for performing research queries across a large number of studies and experiments from different biological and chemical assays, data types and organisms, as well as systems to build and add to such an infrastructure.Type: GrantFiled: December 18, 2006Date of Patent: September 25, 2012Assignee: NextBioInventors: Ilya Kupershmidt, Qiaojuan Jane Su, Francois Andry
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Publication number: 20100318528Abstract: According to various embodiments, aspects of the invention provide a highly efficient meta-analysis infrastructure for performing research queries across a large number of studies and experiments from diverse sequencing technologies as well as different biological and chemical assays, data types and organisms, as well as systems to build and add to such an infrastructure. The methods, systems and apparatuses described enable combining orthogonal types of data and available public knowledge to elucidate mechanisms governing normal development, disease progression, as well as susceptibility of individuals to disease or response to drug treatments.Type: ApplicationFiled: June 8, 2010Publication date: December 16, 2010Applicant: NextBioInventors: Ilya Kupershmidt, Qiaojuan Jane Su
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Publication number: 20090222400Abstract: The present invention relates to methods, systems and apparatus for capturing, integrating, organizing, navigating and querying large-scale data from high-throughput biological and chemical assay platforms. It provides a highly efficient meta-analysis infrastructure for performing research queries across a large number of studies and experiments from different biological and chemical assays, data types and organisms, as well as systems to build and add to such an infrastructure. According to various embodiments, methods, systems and interfaces for associating experimental data, features and groups of data related by structure and/or function with chemical, medical and/or biological terms in an ontology or taxonomy are provided. According to various embodiments, methods, systems and interfaces for filtering data by data source information are provided, allowing dynamic navigation through large amounts of data to find the most relevant results for a particular query.Type: ApplicationFiled: March 4, 2009Publication date: September 3, 2009Applicant: NextBioInventors: Ilya Kupershmidt, Qiaojuan Jane Su, Qingdi Liu, Satnam Alag, Suman Sundaresh
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Publication number: 20090049019Abstract: The present invention relates to methods, systems and apparatus for capturing, integrating, organizing, navigating and querying large-scale data from high-throughput biological and chemical assay platforms. It provides a highly efficient meta-analysis infrastructure for performing research queries across a large number of studies and experiments from different biological and chemical assays, data types and organisms, as well as systems to build and add to such an infrastructure. In particular, aspects of the invention relate to integrating, organizing, navigating and querying “directional” data, such as gene expression profiles.Type: ApplicationFiled: September 19, 2008Publication date: February 19, 2009Applicant: NextBioInventors: Qiaojuan Jane SU, Ilya Kupershmidt