Patents Assigned to Nichirei Biosciences Inc.
  • Patent number: 8575368
    Abstract: This invention provides useful applications of cashew apple. This invention also provides a naturally occurring active ingredient having useful activities, such as alpha-amylase inhibitory activity, lipase inhibitory activity, and antibacterial activity against Propionibacterium acnes. The invention also provides a composition containing cashew apple-derived proanthocyanidin having excellent alpha-amylase inhibitory activity, lipase inhibitory activity, and antibacterial activity against Propionibacterium acnes, which is prepared by allowing a plant fiber-degrading enzyme (e.g., pectinase) to react with a cashew apple and concentrating the resultant with the use of an ultrafiltration membrane. Further, the invention provides a proanthocyanidin compound having a novel structure.
    Type: Grant
    Filed: June 25, 2009
    Date of Patent: November 5, 2013
    Assignee: Nichirei Biosciences, Inc.
    Inventor: Kenichi Nagamine
  • Publication number: 20120295279
    Abstract: Disclosed are a pretreatment solution for immunohistochemical staining, which elutes a paraffin-containing embedding medium from a glass slide with a tissue specimen embedded in the medium, and retrieves antigenicity of the tissue specimen, and which is usable three or more times, and a pretreatment solution concentrate for immunohistochemical staining which allows ready preparation of the pretreatment solution. The pretreatment solution for immunohistochemical staining contains an antigen retrieving agent, particular nonionic surfactants, and cyclodextrin or a derivative thereof, with the balance being not less than 80 mass % of water. The content of the antigen retrieval agent is such that the pH of the pretreatment solution is in a predetermined range, and the content of cyclodextrin or a derivative thereof is a particular amount.
    Type: Application
    Filed: February 3, 2011
    Publication date: November 22, 2012
    Applicant: NICHIREI BIOSCIENCES INC.
    Inventor: Toshiyuki Kasamatsu
  • Publication number: 20110263698
    Abstract: This invention provides useful applications of cashew apple. This invention also provides a naturally occurring active ingredient having useful activities, such as alpha-amylase inhibitory activity, lipase inhibitory activity, and antibacterial activity against Propionibacterium acnes. The invention also provides a composition containing cashew apple-derived proanthocyanidin having excellent alpha-amylase inhibitory activity, lipase inhibitory activity, and antibacterial activity against Propionibacterium acnes, which is prepared by allowing a plant fiber-degrading enzyme (e.g., pectinase) to react with a cashew apple and concentrating the resultant with the use of an ultrafiltration membrane. Further, the invention provides a proanthocyanidin compound having a novel structure.
    Type: Application
    Filed: June 25, 2009
    Publication date: October 27, 2011
    Applicant: NICHIREI BIOSCIENCES, INC.
    Inventor: Kenichi Nagamine
  • Patent number: 7935673
    Abstract: It is an objective of the present invention to provide a polyphenol glycoside isolated from acerola, which has a binding mode that has not been conventionally known, and to provide the use of the same. The present invention relates to a compound represented by formula (I): and an antioxidant, a glucosidase inhibitor, a food, a cosmetic, and a skin preparation for external use, each of which comprises such compound.
    Type: Grant
    Filed: December 12, 2005
    Date of Patent: May 3, 2011
    Assignee: Nichirei Biosciences, Inc.
    Inventors: Masakazu Kawaguchi, Kenichi Nagamine
  • Publication number: 20100267659
    Abstract: This invention relates to an extract obtained from a plant of the genus Odontoglossum of the family Orchidaceae, or from a plant derived from a hybrid plant of the genus Odontoglossum and the genus Cochlioda, to a method for preparing the extract, and to an external agent for skin comprising the extract.
    Type: Application
    Filed: March 27, 2009
    Publication date: October 21, 2010
    Applicant: NICHIREI BIOSCIENCES INC.
    Inventors: Akiko Sasaki, Masakazu Kawaguchi, Ayaka Himono
  • Publication number: 20100029918
    Abstract: It is an objective of the present invention to provide a polyphenol glycoside isolated from acerola, which has a binding mode that has not been conventionally known, and to provide the use of the same. The present invention relates to a compound represented by formula (I): and an antioxidant, a glucosidase inhibitor, a food, a cosmetic, and a skin preparation for external use, each of which comprises such compound.
    Type: Application
    Filed: December 12, 2005
    Publication date: February 4, 2010
    Applicant: NICHIREI BIOSCIENCES INC.
    Inventors: Masakazu Kawaguchi, Kenichi Nagamine
  • Publication number: 20100022973
    Abstract: [Problems] An object of the present invention is to develop a sheet-shaped base material or a container having a structure which is designed in such a manner that snot or phlegm is collected as a biological excretory substance and said biological excretory substance is able to be easily applied to a test in medical therapy and also to develop a system where the biological excretory substance is collected using the same. [Solving Means] A biological excretory substance is collected using a bag-shaped container constituted from a sheet-shaped base material comprising a soft porous material only, a soft nonporous material only or a compounded material of a soft nonporous material and a soft porous material and then it is retained in the container.
    Type: Application
    Filed: June 1, 2006
    Publication date: January 28, 2010
    Applicant: Nichirei Biosciences Inc.
    Inventors: Hirohisa Matsushita, Hideyuki Ikematsu
  • Publication number: 20080267894
    Abstract: The present invention relates to a pectin derived from an acerola fruit or a hydrolysate thereof, comprising a complex formed of Aceronidin, which is a novel polyphenol compound. The pectin of the present invention can be used as an active ingredient of an antioxidant or a skin-whitening agent.
    Type: Application
    Filed: February 28, 2006
    Publication date: October 30, 2008
    Applicants: NICHIREI FOODS INC., NICHIREI BIOSCIENCES INC.
    Inventors: Masakazu Kawaguchi, Akiko Sasaki, Kenichi Nagamine, Jun Kamihigashi
  • Patent number: 7235369
    Abstract: A complex of enzyme, protein and carrier comprising two or more molecules of an enzyme conjugated through an amino group or other group to a carrier such as polylysine, and a protein (for example, antibody) with a specific binding potency to other substance(s) (for example, antigen) conjugated to at least one of said two or more molecules of the enzyme. This complex enables accurate assay of a trace amounts of a substance at a high sensitivity.
    Type: Grant
    Filed: June 30, 2003
    Date of Patent: June 26, 2007
    Assignee: Nichirei Biosciences Inc.
    Inventors: Hirokazu Ohbayashi, Yuriko Kitano
  • Patent number: 7192617
    Abstract: The invention relates to a whitening agent that makes effective use of camu camu seeds, which have conventionally been discarded, and that has high safety and whitening effect useful in cosmetics and the like, as well as skin preparations for external use and cosmetics containing the whitening agent. The whitening agent of the present invention contains camu camu seed extract as an active component, and the skin preparations for external use and cosmetics of the present invention contain the whitening agent.
    Type: Grant
    Filed: December 8, 2003
    Date of Patent: March 20, 2007
    Assignee: Nichirei Biosciences Inc.
    Inventors: Kenichi Nagamine, Miki Hayashi, Kaori Yamasaki
  • Patent number: 7090872
    Abstract: The invention relates to antioxidants that make effective use of acerola seeds, which have conventionally been discarded, that have high safety and excellent antioxidative effect in skin preparations for external use, cosmetics, and food, and that contain acerola seed extract as an active component. The invention also relates to skin preparations for external use, cosmetics, and food containing the antioxidant.
    Type: Grant
    Filed: November 21, 2003
    Date of Patent: August 15, 2006
    Assignee: Nichirei Biosciences Inc.
    Inventors: Kenichi Nagamine, Miki Hayashi, Kaori Yamasaki
  • Patent number: 7074907
    Abstract: The compound of the present invention is a component originated from a natural material, camu camu (Myrciaria dubia), has strong antioxidative activity and stable whitening effect, and is represented by the formula (1).
    Type: Grant
    Filed: December 24, 2003
    Date of Patent: July 11, 2006
    Assignee: Nichirei Biosciences Inc.
    Inventors: Kenichi Nagamine, Miki Hayashi, Kaori Yamasaki
  • Publication number: 20060104927
    Abstract: The compound of the present invention is a component originated from a natural material, camu camu (Myrciaria dubia), has strong antioxidative activity and stable whitening effect, and is represented by the formula (1). The antioxidant, whitening agent, skin preparation for external use, cosmetics, and food of the present invention are characterized by the inclusion of the compound represented by the formula (1).
    Type: Application
    Filed: December 24, 2003
    Publication date: May 18, 2006
    Applicant: Nichirei Biosciences Inc.
    Inventors: Kenichi Nagamine, Miki Hayashi, Kaori Yamasaki
  • Publication number: 20060104926
    Abstract: The invention relates to a whitening agent that makes effective use of camu camu seeds, which have conventionally been discarded, and that has high safety and whitening effect useful in cosmetics and the like, as well as skin preparations for external use and cosmetics containing the whitening agent. The whitening agent of the present invention contains camu camu seed extract as an active component, and the skin preparations for external use and cosmetics of the present invention contain the whitening agent.
    Type: Application
    Filed: December 8, 2003
    Publication date: May 18, 2006
    Applicant: Nichirei Bioscience Inc.
    Inventors: Kenichi Nagamine, Miki Hayashi, Kaori Yamasaki
  • Publication number: 20060051439
    Abstract: The invention relates to antioxidants that make effective use of acerola seeds, which have conventionally been discarded, that have high safety and excellent antioxidative effect in skin preparations for external use, cosmetics, and food, and that contain acerola seed extract as an active component. The invention also relates to skin preparations for external use, cosmetics, and food containing the antioxidant.
    Type: Application
    Filed: November 21, 2003
    Publication date: March 9, 2006
    Applicant: Nichirei Biosciences Inc.
    Inventors: Kenichi Nagamine, Miki Hayashi, Kaori Yamasaki