Abstract: A pharmaceutical composition comprising: (a) a pharmaceutically effective amount of meloxicam, or a pharmaceutically acceptable salt thereof; (b) a skin permeation enhancing agent selected from the group consisting of: (i) an amine of formula I wherein: R1, R2, and R3 are each independently an alkanolyl group with 1 to 24 C-atoms, in which one or more H-atoms are optionally substituted by —OH and/or one or more —CH2— groups are optionally substituted by —O—, or a polyoxyethylene group with 2 to 30 ethylene oxide units, and R2 and R3 are additionally independently H or a linear, branched, or cyclic alkyl group with 1 to 24 C-atoms, in which one or more —CH2— groups are optionally substituted by —CH?CH— and/or —O— and/or in which one or more H-atoms are optionally substituted by —OH, and (ii) an amide of formula II wherein: R4 and R5 are each independently a linear, branched, or cyclic alkyl group with 1 to 24 C-atoms, in which one or more —CH2— groups are optionally substituted by —CH?CH—and/or —O— an