Abstract: Provided are: a monoclonal antibody against human IgG4, for which the epitope is present in the CH3 of human IgG4 given by SEQ ID NO: 4; a hybridoma that produces the monoclonal antibody; a method for detecting IgG4 using the monoclonal antibody; and a kit used in this method.
Abstract: The present invention addresses the problem of providing a novel method for classifying cancer cells by an analysis method in which measurement of the activity of two types of protein kinase is used. Cancer cells are newly classified and drug sensitivity is predicted on the basis of the ratio of the activity of two types of protein kinase derived from the same sample.
Abstract: Provided are a copolymer of diallylamines and sulfur dioxide having a high molecular weight and a low content amount of impurities such as halogens, and a production method with which it is possible to produce such a copolymer relatively simply and at low cost. This problem is solved by: a copolymer having a weight-average molecular weight of 150,000 or higher obtained by GPC measurement and a degree of polymerization of 1000 or higher, the copolymer being obtained by copolymerizing sulfur dioxide and a sulfonate or alkyl sulfate salt of diallylamines having a specific structure; and a method for producing a copolymer, the method having a step for copolymerizing sulfur dioxide and a sulfonate or alkyl sulfate salt of diallylamines having a specific structure in ethylene glycol or in propylene glycol monomethyl ether.
Abstract: Provided is a glass cloth enabling to reduce a mass of the glass cloth, being manufactured efficiently, suppressing generation of pinholes in a prepreg including the glass cloth, and maintaining excellent appearance. The glass cloth is composed of warps and wefts obtained by bundling 30 to 44 glass filaments having a diameter in the range of 3.0 to 4.0 ?m, the weave densities of the warp and the weft being in the range of 100 to 125 yarns/25 mm; the glass cloth has a thickness in the range of 6.5 to 11.0 ?m; the glass yarn coverage C is 85.5 to 99.5%; and the glass yarn coverage C, the average value F of the number of glass filaments constituting the warp and the weft, and the average value D of the weave densities of the warp and the weft satisfy the following expression (1): 53.0?C×F1/2/D1/2?57.3??(1).
Abstract: The glass-fiber-yarn joined body 1 is provided with glass fiber yarns 2, 3, and a connection 5 in which a resin yarn 4 is wound around ends of both of the glass fiber yarns 2, 3, the ends being superimposed with each other. The connection 5 has a width W1 of 20 to 40 mm. When a connection diameter R as a total of diameters of the respective glass fiber yarns 2, 3 and the thickness of the resin yarn 4 wound around the connection 5 is 500 to 5000 ?m and a mass of each of the glass fiber yarns 2, 3 is 200 to 6000 tex, a value of a ratio of mass of each of the glass fiber yarns 2, 3 relative to the connection diameter R is in the range of 0.32 to 2.00.
Abstract: Provided are a pretreatment method for detecting the number of cells containing Ki-67 protein-positive nuclei using Ki-67 antibody; a method for the detection; a kit to be used in the detection method; and determination of a therapy regimen using the aforesaid method. Attempts were made to activate Ki-67 antigen with the use of an enzyme having been considered as inappropriate for the activation thereof. By pretreating a sample with an enzyme not recognizing the epitope of MIB-1 (a rare cutter enzyme), the antigen activation of Ki-67 antigen was enhanced, while enhancing the antigenicity of other antigens including a cytokeratin too. As a result, a method for more objectively and more universally quantifying Ki-67-positive cells at higher reproducibility, said method comprising isolating cell nuclei from an FFPE section while enhancing the antigenicity and performing a reaction between Ki-67 protein, i.e., the target, existing in the cell nuclei with a fluorescently labeled antibody, has been completed.
Type:
Application
Filed:
February 28, 2019
Publication date:
December 31, 2020
Applicant:
NITTO BOSEKI CO., LTD.
Inventors:
Natsuki SATO, Mika KUROIWA, Masatoshi NAKATSUJI, Hideki ISHIHARA
Abstract: The present invention addresses the problem of providing a novel method for classifying cancer cells by an analysis method in which measurement of the activity of two types of protein kinase is used. Cancer cells are newly classified and drug sensitivity is predicted on the basis of the ratio of the activity of two types of protein kinase derived from the same sample.
Abstract: Provided is a glass composition for glass fiber having a low dielectric constant and a low dielectric loss tangent, suppressing occurrence of phase separation, and reducing viscosity at high temperatures. The glass composition for glass fiber includes: SiO2 in the range of 52.0 to 59.5% by mass; B2O3 in the range of 17.5 to 25.5% by mass; Al2O3 in the range of 9.0 to 14.0% by mass; SrO in the range of 0.5 to 6.0% by mass; MgO in the range of 1.0 to 5.0% by mass; and CaO in the range of 1.0 to 5.0% by mass, and includes F2 and Cl2 in the range of 0.1 to 2.5% by mass in total, with respect to the total amount.
Abstract: Disclosed is a test instrument for measuring an analyte in a liquid sample by a noble metal colloid aggregation measurement method. The test instrument involves a reaction chamber in which at least the liquid sample is to be reacted with a reagent, wherein the reagent is adhered on at least a part of a surface constituting the reaction chamber in a dried state, and the reagent enables the measurement of the analyte by a noble metal colloid aggregation measurement method.
Abstract: Even when used in applications such as electronic materials, display materials, and inks, in which required standards in terms of coloring prevention, long term stability, low impurity content, and the like, are extremely high, the present invention can meet such required standards. The present invention addresses the problem of providing an allylamine (co)polymer which overcomes the limitations of the prior art, undergoes little coloring, contains little impurities and exhibits excellent long term stability; and a method for producing the same. This problem can be solved by an allylamine (co)polymer which has constituent units derived from allylamine and contains sulfuric acid groups in the structure thereof, in which the proportion of the sulfuric acid groups with respect to the total mass of the allylamine (co)polymer is 20,000 ppm by mass or less.
Abstract: Provided is a glass fiber-reinforced resin molded article having excellent mechanical strength, heat resistance, long-term durability, and molding processability. This glass fiber-reinforced resin molded article is characterized in that glass fibers contained in the glass fiber-reinforced resin molded article have a fiber diameter D (?m) in a range from 3.0 to 12.0 ?m; the glass fibers contained in the glass fiber-reinforced resin molded article have a number-average fiber length L (?m) in a range from 160 to 350 ?m; the glass fiber-reinforced resin molded article has a glass fiber volume fraction V (%) in a range from 3.0 to 50.0%; and D, L, and V satisfy formula (1): 300.0?D2×L/V?1000.0??(1).
Abstract: Provided are a copolymer of diallylamines and sulfur dioxide having a high molecular weight and a low content amount of impurities such as halogens, and a production method with which it is possible to produce such a copolymer relatively simply and at low cost. This problem is solved by: a copolymer having a weight-average molecular weight of 150,000 or higher obtained by GPC measurement and a degree of polymerization of 1000 or higher, the copolymer being obtained by copolymerizing sulfur dioxide and a sulfonate or alkyl sulfate salt of diallylamines having a specific structure; and a method for producing a copolymer, the method having a step for copolymerizing sulfur dioxide and a sulfonate or alkyl sulfate salt of diallylamines having a specific structure in ethylene glycol or in propylene glycol monomethyl ether.
Abstract: Provided are a copolymer of diallylamines and sulfur dioxide having a high molecular weight and a low content amount of impurities such as halogens, and a production method with which it is possible to produce such a copolymer relatively simply and at low cost. This problem is solved by: a copolymer having a weight-average molecular weight of 150,000 or higher obtained by GPC measurement and a degree of polymerization of 1000 or higher, the copolymer being obtained by copolymerizing sulfur dioxide and a sulfonate or alkyl sulfate salt of diallylamines having a specific structure; and a method for producing a copolymer, the method having a step for copolymerizing sulfur dioxide and a sulfonate or alkyl sulfate salt of diallylamines having a specific structure in ethylene glycol or in propylene glycol monomethyl ether.
Abstract: The purpose of the present invention is to provide a method for separating and concentrating a target substance as an alternative to existing cationic polymers, and a kit for implementing this method.
Abstract: The purpose of the present invention is to provide a monoclonal antibody that is useful in specifically assaying tartrate resistant acid phosphatase 5b (TRACP-5b). A hybridoma producing a monoclonal antibody against TRACP-5b, said monoclonal antibody showing higher reactivity with TRACP-5b than with tartrate resistant acid phosphatase 5a (TRACP-5a) and, therefore, being specific to TRACP-5b, is obtained by cell fusion using, as an antigen, human recombinant TRACP-5b purified from silkworm silk gland. By using this monoclonal antibody, TRACP-5b in a specimen can be highly sensitively and specifically detected.
Abstract: In a glass chopped strand mat, a short chopped strand layer having first glass chopped strands with an average length of 25.4 to 76.2 mm and a long chopped strand layer having second glass chopped strands with an average length of 76.2 to 203.2 mm are laminated, a difference between the average length of the first glass chopped strands and that of the second glass chopped strands is 25.4 mm or greater, the short chopped strand layer occupies 50 to 70 parts by mass, and the long chopped strand layer occupies 30 to 50 parts by mass with respect to 100 parts by mass of the glass chopped strand mat, a mass per unit area of the glass chopped strand mat is 180 g/m2 or lower, and a loss on ignition of the glass chopped strand mat measured on the basis of JIS R 3420 is lower than 10%.
Abstract: Provided are: a graft copolymer which can be safely and stably produced with simple operation, while maintaining the characteristics of an amine, and which is lower in the introduction cost than conventional graft copolymers; and a method for producing the graft copolymer. A polyamine graft polymer that is obtained by polymerizing a polyamine derivative, which is obtained by reacting a polymer compound (a) having at least one amino group with a compound (b) having at least one epoxy group, with an ethylenically unsaturated monomer (c). A method for producing a polyamine graft polymer, which comprises a step for adding, for polymerization, an ethylenically unsaturated monomer (c) and a radical polymerization initiator to a polyamine derivative, which is obtained by reacting a polymer compound (a) having at least one amino group with a compound (b) having at least one epoxy group, in a polar solvent.
Abstract: In a glass chopped strand mat, a short chopped strand layer having first glass chopped strands with an average length of 25.4 to 76.2 mm and a long chopped strand layer having second glass chopped strands with an average length of 76.2 to 203.2 mm are laminated, a difference between the average length of the first glass chopped strands and that of the second glass chopped strands is 25.4 mm or greater, the short chopped strand layer occupies 50 to 70 parts by mass, and the long chopped strand layer occupies 30 to 50 parts by mass with respect to 100 parts by mass of the glass chopped strand mat, a mass per unit area of the glass chopped strand mat is 180 g/m2 or lower, and a loss on ignition of the glass chopped strand mat measured on the basis of JIS R 3420 is lower than 10%.
Abstract: Provided is a glass fiber fabric-resin composition laminate which is thinner than the conventional glass fiber fabric-resin composition laminates and has a strength equal to or higher than that of the conventional laminates. In the glass fiber fabric-resin composition laminate 1, one or more layers of first glass fiber fabrics 2 to 5 have a total thickness of 50 to 100% with respect to the overall thickness. The glass composition of the first glass fiber fabrics 2 to 5 is 57 to 70 mass % of SiO2, 18 to 30 mass % of Al2O3, 5 to 15 mass % of MgO, 0 to 12 mass % of CaO, 0 to 1 mass % of at least one of Li2O, Na2O, and K2O, 0 to 1 mass % of TiO2, and 0 to 1 mass % of B2O3.
Type:
Grant
Filed:
October 16, 2014
Date of Patent:
July 24, 2018
Assignee:
Nitto Boseki Co., Ltd.
Inventors:
Dai Sakuma, Noriyoshi Sato, Toshihiro Tashiro
Abstract: Provided are a copolymer of diallylamines and sulfur dioxide having a high molecular weight and a low content amount of impurities such as halogens, and a production method with which it is possible to produce such a copolymer relatively simply and at low cost. This problem is solved by: a copolymer having a weight-average molecular weight of 150,000 or higher obtained by GPC measurement and a degree of polymerization of 1000 or higher, the copolymer being obtained by copolymerizing sulfur dioxide and a sulfonate or alkyl sulfate salt of diallylamines having a specific structure; and a method for producing a copolymer, the method having a step for copolymerizing sulfur dioxide and a sulfonate or alkyl sulfate salt of diallylamines having a specific structure in ethylene glycol or in propylene glycol monomethyl ether.