Patents Assigned to Nobel Ilaç Sanayii Ve Ticaret A.S.
  • 1-(dimethylamino)ethyl-substituted 6H-benzo[C]chromen-6-ones against senile dementia
    Patent number: 9586925
    Abstract: This invention relates to novel (±)1-(Dimethylamino)ethyl substituted 6H-benzo[c]chromen-6-one compounds which are useful as pharmaceutical compositions.
    Type: Grant
    Filed: February 6, 2014
    Date of Patent: March 7, 2017
    Assignee: NOBEL ILAÇ SANAYII VE TICARET A.S.
    Inventors: Hayrettin Ozan Gulcan, Serdar Unlu, Ilker Esiringu, Yasemin Sahin, Tugba Ercetin, Demet Oz, Fethi Sahin
  • 1 -(DIMETHYLAMINO)ETHYL-SUBSTITUTED 6H-BENZO[C]CHROMEN-6-ONES AGAINST SENILE DEMENTIA
    Publication number: 20160002194
    Abstract: This invention relates to novel (±)1-(Dimethylamino)ethyl substituted 6H-benzo[c]chromen-6-one compounds which are useful as pharmaceutical compositions.
    Type: Application
    Filed: February 6, 2014
    Publication date: January 7, 2016
    Applicant: NOBEL ILAÇ SANAYII VE TICARET A.S
    Inventors: Hayrettin Ozan GULCAN, Serdar UNLU, Ilker ESIRINGU, Yasemin SAHIN, Tugba ERCETIN, Demet OZ, Fethi SAHIN
  • Method for the synthesis of rasagiline
    Patent number: 8901352
    Abstract: We have developed a new method for the synthesis of Rasagiline (Formula 1) based on the alkylation of trifluoroacetyl protected aminoindan. This protection enabled us to carry out an alkylation of aminoindan with a high yield and purity under very mild conditions with a wide range of reaction conditions and reagent selection. Considering the ease, purity and high yields of introducing and removal of the trifluoroacetyl group, this approach is a highly practical and economical way for the synthesis of rasagiline or its pharmaceutically acceptable salts.
    Type: Grant
    Filed: January 13, 2011
    Date of Patent: December 2, 2014
    Assignee: Nobel Ilaç Sanayii Ve Ticaret A.S.
    Inventors: Ömer Reis, Hasan Koyuncu, Ilker Esiringu, Yasemin Sahin, H. Ozan Gulcan