Patents Assigned to Nobelpharma Co., Ltd.
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Publication number: 20230293510Abstract: It is an object of the present invention to provide a novel patch for alleviating or treating the symptoms of neurodegenerative disease. According to the present invention, provided is a patch for alleviating or treating the symptoms of neurodegenerative disease, comprising a scopolamine salt and/or a hydrate thereof, wherein the application time of the patch per application is within 48 hours.Type: ApplicationFiled: August 30, 2021Publication date: September 21, 2023Applicant: NOBELPHARMA CO., LTD.Inventors: Takayuki OGAWA, Kenta NISHIMURA, Hiroaki UENO, Yuhei TANI, Mieko OGINO, Koki SATO, Hisanori HATSUKAIWA, Katsunori MIYOSHI, Takahiro INOUE
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Patent number: 11523908Abstract: Object: Provided is a dysphonia treatment tool in which a front surface piece is bent. Resolution means: A dysphonia treatment tool includes a plurality of clamping sections (1, 1) each including a front surface piece (1a) disposed from a cut end surface of thyroid cartilage incised to a front surface, and a rear surface piece (1b) disposed on a rear surface of the thyroid cartilage, and being fitted respectively to cut ends of the thyroid cartilage that are opposite each other, and a bridging section (2) linking the plurality of clamping sections (1, 1) to each other. The front surface piece (1a) is bent in an intermediation section between a base end and a distal end of the front surface piece (1a).Type: GrantFiled: December 29, 2016Date of Patent: December 13, 2022Assignee: NOBELPHARMA CO., LTD.Inventors: Nobuhiko Isshiki, Takako Aburada
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Patent number: 11517424Abstract: The present invention provides a jig for forming a dysphonia treatment tool, the jig being capable of bending a front piece in a position not through a hole. A jig 20C for forming a dysphonia treatment tool X by deformation, the dysphonia treatment tool X including: a plurality of clamping sections each having a front piece 1a disposed on a front surface of incised thyroid cartilage and a rear piece disposed on a rear surface of the thyroid cartilage, the clamping sections configured to be fit to respective cut ends of the thyroid cartilage facing each other; and a bridging section linking the clamping sections to each other, the front piece having a hole 3 formed therein, the forming jig includes a clip section 22 having a pair of maintaining sections 21a, 21b configured to sandwich the front piece 1a from both surfaces to cover at least a portion of the hole 3.Type: GrantFiled: June 13, 2018Date of Patent: December 6, 2022Assignee: Nobelpharma Co., Ltd.Inventor: Takako Aburada
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Publication number: 20220160697Abstract: A medicinal composition containing a scopolamine salt and/or a hydrate thereof, polyvinylpyrrolidone, and a base. The medicinal composition is excellent in terms of absorption of the drug into the living body and chemical stability thereof.Type: ApplicationFiled: March 6, 2020Publication date: May 26, 2022Applicants: NOBELPHARMA CO., LTD., YUTOKU PHARMACEUTICAL INDUSTRIES CO., LTD.Inventors: Takayuki OGAWA, Kenta NISHIMURA, Hiroaki UENO, Yuhei TANI
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Patent number: 11051985Abstract: [Problem] The present invention provides a preparation jig for a tympanic membrane regenerating agent and a preparation vessel for a tympanic membrane regenerating agent enabling simple preparation of a tympanic membrane regenerating agent. [Solution] A preparation jig for a tympanic membrane regenerating agent (1a) and a preparation vessel for a tympanic membrane regenerating agent (1A) each include: a vessel (3A) including housing walls (6, 7) forming an interior space (S1) housing a medicinal solution support (2), and including an opening (6h) opening in one direction and formed in the housing walls (6, 7); and a holding portion (4A) disposed in the interior space (S1). The deep side of the interior space (S1) is a housing portion (S3) housing the medicinal solution support (2) holding a medicinal solution. The opening (6h) side of the interior space (S1) is an installation space (S2) in which the holding portion (4A) is disposed.Type: GrantFiled: September 30, 2016Date of Patent: July 6, 2021Assignee: Nobelpharma Co., Ltd.Inventors: Takako Aburada, Shinobu Yamada
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Patent number: 11001557Abstract: The present invention pertains to an antiviral drug for severe fever with thrombocytopenia syndrome, which contains a compound represented by formula (I) or a salt thereof, or a solvate of the compound or salt (In the formula, R1 and R2 are the same or different from each other, and each represents a substituted or unsubstituted C1-10 alkyl group, R1 and R2 may form a substituted or unsubstituted 5- or 6-member ring in conjunction with an adjacent nitrogen atom, and X represent a halogen atom.Type: GrantFiled: January 16, 2018Date of Patent: May 11, 2021Assignees: Kagoshima University, Nobelpharma Co., Ltd.Inventors: Masanori Baba, Masaaki Toyama, Norikazu Sakakibara
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Patent number: 10813765Abstract: [Problem] The present invention provides a voice disorder treatment tool in which a clamping section thereof does not break easily. [Solution] The present invention includes a plurality of clamping sections 1, 1 that are provided with a front surface piece 1b disposed on a front surface 11a of incised thyroid cartilage 11 and a rear surface piece 1c disposed on a rear surface of the thyroid cartilage 11, and fit to cut ends 12 of the incised thyroid cartilage 11 that are facing each other, and a bridging section 2 that connects the plurality of clamping sections 1, 1. The front surface piece 1b includes a bending region 15 deformable about a virtual line K extending in a width direction of this front surface piece 1b, and the bending region 15 has a reinforcing structure S.Type: GrantFiled: August 9, 2016Date of Patent: October 27, 2020Assignees: NOBELPHARMA CO., LTD., NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY, WAKAYOSHI SEISAKUSHO CO., LTD.Inventors: Tetsuji Sanuki, Shuji Wakayoshi, Tsukasa Harada, Seiichi Masuda, Hiroyuki Nishihata, Kazuhiro Kinoshita, Takako Aburada
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Publication number: 20190389803Abstract: The present invention pertains to an antiviral drug for severe fever with thrombocytopenia syndrome, which contains a compound represented by formula (I) or a salt thereof, or a solvate of the compound or salt (In the formula, R1 and R2 are the same or different from each other, and each represents a substituted or unsubstituted C1-10 alkyl group, R1 and R2 may form a substituted or unsubstituted 5- or 6-member ring in conjunction with an adjacent nitrogen atom, and X represent a halogen atom.Type: ApplicationFiled: January 16, 2018Publication date: December 26, 2019Applicants: Kagoshima University, Nobelpharma Co., Ltd.Inventors: Masanori BABA, Masaaki TOYAMA, Norikazu SAKAKIBARA
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Patent number: 10369159Abstract: [Problem] To provide a therapeutic agent for estrogen-dependent gynecological diseases such as endometriosis, uterine fibroids, and uterus adenomyosis. [Solution] To use an estrogen receptor ?-inhibiting ? partial agonist represented by the formula (a), a pharmaceutically-acceptable salt thereof, or a hydrate of either of the afore-mentioned, as an active ingredient.Type: GrantFiled: September 21, 2018Date of Patent: August 6, 2019Assignees: Nobelpharma Co., Ltd., National University Corporation Tottori UniversityInventors: Kenichiro Nakao, Tasuku Harada, Fuminori Taniguchi
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Patent number: 10357595Abstract: Provided is a tympanic membrane or ear canal regeneration agent comprising a combination of a gelatin sponge that carries basic fibroblast growth factor (bFGF) and a covering material. The covering material is used not only to fix the gelatin sponge to the affected portion, but also for the purpose of preventing drying and infections to provide a culturing environment that is favorable for regenerating tissue isolated from the outside. To promote tissue regeneration, the margin of the tympanic membrane or ear canal defect is preferably freshened in advance.Type: GrantFiled: October 12, 2018Date of Patent: July 23, 2019Assignee: NOBELPHARMA CO., LTD.Inventor: Shin-ichi Kanemaru
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Publication number: 20190038811Abstract: Provided is a tympanic membrane or ear canal regeneration agent comprising a combination of a gelatin sponge that carries basic fibroblast growth factor (bFGF) and a covering material. The covering material is used not only to fix the gelatin sponge to the affected portion, but also for the purpose of preventing drying and infections to provide a culturing environment that is favorable for regenerating tissue isolated from the outside. To promote tissue regeneration, the margin of the tympanic membrane or ear canal defect is preferably freshened in advance.Type: ApplicationFiled: October 12, 2018Publication date: February 7, 2019Applicant: NOBELPHARMA CO., LTD.Inventor: Shin-ichi Kanemaru
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Patent number: 10117969Abstract: Provided is a tympanic membrane or ear canal regeneration agent comprising a combination of a gelatin sponge that carries basic fibroblast growth factor (bFGF) and a covering material. The covering material is used not only to fix the gelatin sponge to the affected portion, but also for the purpose of preventing drying and infections to provide a culturing environment that is favorable for regenerating tissue isolated from the outside. To promote tissue regeneration, the margin of the tympanic membrane or ear canal defect is preferably freshened in advance.Type: GrantFiled: September 9, 2015Date of Patent: November 6, 2018Assignee: NOBELPHARMA CO., LTD.Inventor: Shin-ichi Kanemaru
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Patent number: 9161904Abstract: Provided is a tympanic membrane or ear canal regeneration agent comprising a combination of a gelatin sponge that carries basic fibroblast growth factor (bFGF) and a covering material. The covering material is used not only to fix the gelatin sponge to the affected portion, but also for the purpose of preventing drying and infections to provide a culturing environment that is favorable for regenerating tissue isolated from the outside. To promote tissue regeneration, the margin of the tympanic membrane or ear canal defect is preferably freshened in advance.Type: GrantFiled: June 26, 2009Date of Patent: October 20, 2015Assignee: Nobelpharma Co., Ltd.Inventor: Shin-ichi Kanemaru