Patents Assigned to NovaBay Pharmaceuticals, Inc.
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Patent number: 9625744Abstract: The present invention relates generally to systems and methods for cleaning and disinfecting contact lenses. In various respects, the invention is directed to an insulated system that reduces heat loss from catalyzed neutralization of a disinfecting solution resulting in an increased temperature of the disinfection solution during the disinfection process and neutralization of the disinfection solution. The increased temperature increases the kill rate (i.e., better reduction) of microorganisms present on the lenses, and increases the neutralization rate of the disinfection solution. Increase of the kill rate allows better reduction of microorganisms resistant to elimination using previous systems and methods, (e.g., Acanthamoeba cysts), and decreases the amount of time as compared to previous systems and methods necessary to reduce microorganisms to acceptable levels.Type: GrantFiled: October 31, 2014Date of Patent: April 18, 2017Assignee: NovaBay Pharmaceuticals, Inc.Inventors: Charles Francavilla, David Stroman
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Publication number: 20170051842Abstract: The present invention relates generally to a magnetic valve system. Embodiments of the present invention provide a system to minimize the potential for mistakenly dispensing one fluid in place of another or desired fluid. More particularly, embodiments of the present invention provide a magnetic valve, where a bias mechanism is provided to bias the magnetic valve into a closed position, whereby a receptacle having a magnet with a magnetic polarity arranged opposite to that of the magnetic valve exerts a force on the magnetic valve sufficient to over come the bias mechanism, and the magnetic valve slides into an open position or state permitting fluid to flow into the receptacle. When the receptacle is removed, the bias mechanism forces the magnetic valve back into the closed position, where no or minimal fluid is permitted to flow.Type: ApplicationFiled: August 20, 2015Publication date: February 23, 2017Applicant: NOVABAY PHARMACEUTICALS, INC.Inventor: Charles Francavilla
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Publication number: 20160346324Abstract: Lipases produced by bacteria break down tear lipids and cause or exacerbate discomfort due to meibomian gland dysfunction, blepharitis or dry eye. In one embodiment, the present invention provides methods of treating and prevention further discomfort by inactivating lipases through use chlorinated solution and or their derivatives.Type: ApplicationFiled: May 27, 2016Publication date: December 1, 2016Applicant: NovaBay Pharmaceuticals, Inc.Inventors: Arthur B. Epstein, Lu Wang, Dmitri Debabov, Kathryn Najafi, Ramin Najafi
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Publication number: 20160331779Abstract: Toxins produced by bacteria promote infection and disease by directly damaging host tissues and by disabling the immune system. In one embodiment, the present application provides methods of treating and prevention further inflammation by inactivating toxins through use positive chlorinated ionic solution and or their derivatives.Type: ApplicationFiled: May 10, 2016Publication date: November 17, 2016Applicant: NovaBay Pharmaceuticals, Inc.Inventors: John CREW, Kathryn Najafi-Tagol, Ron Najafi, Dmitri Debabov, Camron Noorbakhsh, Timothy Shiau, Lu Wang
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Patent number: 9248117Abstract: The present application describes compounds of Formula I: which are antimicrobial agents, including antibacterial, disinfectant, antifungal, germicidal and/or antiviral agents.Type: GrantFiled: October 18, 2011Date of Patent: February 2, 2016Assignee: NOVABAY PHARMACEUTICALS, INC.Inventors: Rakesh K. Jain, Timothy Shiau, Charles Francavilla, Eddy Low, Eric Douglas Turtle, Donogh John Roger O'Mahony
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Publication number: 20150118108Abstract: The present invention relates generally to systems and methods for cleaning and disinfecting contact lenses. In various respects, the invention is directed to an insulated system that reduces heat loss from catalyzed neutralization of a disinfecting solution resulting in an increased temperature of the disinfection solution during the disinfection process and neutralization of the disinfection solution. The increased temperature increases the kill rate (i.e., better reduction) of microorganisms present on the lenses, and increases the neutralization rate of the disinfection solution. Increase of the kill rate allows better reduction of microorganisms resistant to elimination using previous systems and methods, (e.g., Acanthamoeba cysts), and decreases the amount of time as compared to previous systems and methods necessary to reduce microorganisms to acceptable levels.Type: ApplicationFiled: October 31, 2014Publication date: April 30, 2015Applicant: NovaBay Pharmaceuticals, Inc.Inventors: Charles Francavilla, David Stroman
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Patent number: 8851091Abstract: The invention monitors the neutralization process involving hydrogen peroxide solution and a hydrogen peroxide neutralization catalyst and compares measured values with theoretical values. The system monitors the chemical reaction and notifies the user of the neutralization status. In an exemplary embodiment, the initial hydrogen peroxide solution concentration is neutralized with a palladium catalyst after a period of time. A microcontroller analyzes the measurements and displays the neutralization process results using colored LED lights and/or text or images on a LCD display. In one embodiment, an apparatus adapted for use with a cleaning solution used to clean a medical device may include a trigger, a processing device in communication with the trigger, and a display device. The processing device provides a trigger count and the display device communicates with the processing device and displays a message based on the count.Type: GrantFiled: February 23, 2012Date of Patent: October 7, 2014Assignee: NovaBay Pharmaceuticals, IncInventors: Charles Francavilla, Ramin Najafi, Eddy Low, Timothy Shiau, Eric Douglas Turtle, Donogh John Roger O'Mahony
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Patent number: 8729112Abstract: This application describes compounds useful as anti-microbial agents, including as antibacterial, disinfectant, antifungal, germicidal or antiviral agents.Type: GrantFiled: November 14, 2012Date of Patent: May 20, 2014Assignee: Novabay Pharmaceuticals, Inc.Inventors: Timothy Shiau, Charles Francavilla, Eddy Low, Eric Douglas Turtle, Donogh John Roger O'Mahony, Rakesh K. Jain
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Publication number: 20140094495Abstract: This application describes compounds useful as anti-microbial agents, including as antibacterial, disinfectant, antifungal, germicidal or antiviral agents.Type: ApplicationFiled: November 14, 2012Publication date: April 3, 2014Applicant: NovaBay Pharmaceuticals, Inc.Inventors: Timothy K. Shiau, Charles Francavilla, Eddy Low, Eric Douglas Turtle, Donogh John Roger O'Mahony, Rakesh K. Jain
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Patent number: 8415497Abstract: The present invention relates to active bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and antiviral compounds and compositions and to new uses of these compositions in therapy. This specification also describes methods of use for the new compounds and compositions. The specification further describes methods for preparing these compounds.Type: GrantFiled: December 28, 2007Date of Patent: April 9, 2013Assignee: Novabay Pharmaceuticals, Inc.Inventors: Ramin Najafi, Rakesh K. Jain, Timothy P. Shiau, Eddy Low, Satheesh K. Nair
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Patent number: 8278482Abstract: The present application relates to N-chlorinated cationic compounds of Formula I or a salt thereof, and associated compositions and methods of use as antimicrobial agents.Type: GrantFiled: November 6, 2009Date of Patent: October 2, 2012Assignee: Novabay Pharmaceuticals, Inc.Inventors: Rakesh K. Jain, Eddy Low, Charles Francavilla, Timothy P. Shiau, Satheesh K. Nair
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Patent number: 7893109Abstract: The present invention relates to active bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and antiviral compounds and compositions and to new uses of these compositions in therapy. This specification also describes methods of use for the new compounds and compositions. The specification further describes methods for preparing these compounds.Type: GrantFiled: September 11, 2008Date of Patent: February 22, 2011Assignee: Novabay Pharmaceuticals, Inc.Inventors: Mansour Bassiri, Ramin Najafi, Lu Wang, Jane Yang
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Patent number: 7846971Abstract: The present invention relates to active bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and antiviral compounds and compositions and to new uses of these compositions in therapy. This specification also describes methods of use for the new compounds and compositions. The specification further describes methods for preparing these compounds. FIG. 1: A dual chamber apparatus for the preparation of NNDCT on site.Type: GrantFiled: January 25, 2006Date of Patent: December 7, 2010Assignee: Novabay Pharmaceuticals, Inc.Inventors: Ramin Najafi, Mansour Bassiri, Lu Wang, Behzad Khosrovi
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Patent number: 7462361Abstract: The present invention relates to active bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and antiviral compounds and compositions and to new uses of these compositions in therapy. This specification also describes methods of use for the new compounds and compositions. The specification further describes methods for preparing these compounds.Type: GrantFiled: August 17, 2004Date of Patent: December 9, 2008Assignee: Novabay Pharmaceuticals, Inc.Inventors: Mansour Bassiri, Ramin Najafi, Lu Wang, Jane Yang
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Patent number: 7393522Abstract: Described herein is a physiologically-balanced, acidic solution. Typically the solution is prepared by a chemical reactions or by the electrolysis of a solution comprising a mixture of an inorganic salt to form a physiologically balanced solution. This invention also relates to methods for use of the solutions, including a specialized bandage which may be used in combination with the solutions, or optionally with other topically applied materials. A mixture of inorganic salts and, optionally minerals, is used in order to mimic the electrolyte concentration and mixture of body fluid in an isotonic state. The solution typically comprises of one halide salt of lithium, sodium, potassium, calcium, and other cations. Typically the halide is fluoride, chloride, bromide, or iodide, and most typically chloride.Type: GrantFiled: September 3, 2003Date of Patent: July 1, 2008Assignee: NovaBay Pharmaceuticals, Inc.Inventors: Ramin Najafi, Lu Wang, Mansour Bassiri, Jane Yang