Patents Assigned to Novadaq Technologies Inc.
-
Publication number: 20100210904Abstract: A fluorescence endoscopy video system includes a multimode light source that produces light for color and fluorescence imaging modes. Light from the light source is transmitted through an endoscope to the tissue under observation. The system also includes a compact camera for color and fluorescence imaging. Images obtained through the endoscope are optically divided and projected onto one or more image sensors by a fixed beam splitter in the camera. The fixed beam splitter eliminates the need for inserting a movable mirror into the light path between the endoscope and the image sensors. Image signals from the camera are processed in the system processor/controller where a contrast enhancement function can be applied. The contrast enhancement function increases the color contrast between normal tissue and tissue suspicious for early cancer. Finally, the system also includes a calibration feature whereby the system performance can be maintained when used with different endoscopes.Type: ApplicationFiled: April 16, 2010Publication date: August 19, 2010Applicant: Novadaq Technologies Inc.Inventors: Richard W. Cline, John J.P. Fengler, Joachim W. Boehm
-
Publication number: 20100198010Abstract: A fluorescence endoscopy video system includes a multimode light source that produces light for color and fluorescence imaging modes. Light from the light source is transmitted through an endoscope to the tissue under observation. The system also includes a compact camera for color and fluorescence imaging. Images obtained through the endoscope are optically divided and projected onto one or more image sensors by a fixed beam splitter in the camera. The fixed beam splitter eliminates the need for inserting a movable mirror into the light path between the endoscope and the image sensors. Image signals from the camera are processed in the system processor/controller where a contrast enhancement function can be applied. The contrast enhancement function increases the color contrast between normal tissue and tissue suspicious for early cancer. Finally, the system also includes a calibration feature whereby the system performance can be maintained when used with different endoscopes.Type: ApplicationFiled: April 16, 2010Publication date: August 5, 2010Applicant: Novadaq Technologies Inc.Inventors: Richard W. Cline, John J.P. Fengler, Joachim W. Boehm
-
Patent number: 7722534Abstract: A fluorescence endoscopy video system includes a multimode light source that produces light for color and fluorescence imaging modes. Light from the light source is transmitted through an endoscope to the tissue under observation. The system also includes a compact camera for color and fluorescence imaging. Images obtained through the endoscope are optically divided and projected onto one or more image sensors by a fixed beam splitter in the camera. The fixed beam splitter eliminates the need for inserting a movable mirror into the light path between the endoscope and the image sensors. Image signals from the camera are processed in the system processor/controller where a contrast enhancement function can be applied. The contrast enhancement function increases the color contrast between normal tissue and tissue suspicious for early cancer. Finally, the system also includes a calibration feature whereby the system performance can be maintained when used with different endoscopes.Type: GrantFiled: January 7, 2008Date of Patent: May 25, 2010Assignee: Novadaq Technologies, Inc.Inventors: Richard W Cline, John J. P. Fengler, Joachim W. Boehm
-
Publication number: 20100087741Abstract: A method is described for computing a statistically significant difference between dysplasia and Barrett's esophagus (both with and without inflammatory component) using a discriminate function with diffuse reflectance measurements performed at a minimum of four different wavelengths of 485, 513, 598, and 629 nm. The discriminate function found depends both on local blood fraction volume THB and oxygenation SO2. A pull-back approach of spectral data acquisition is disclosed which takes into account tissue motility in esophagus and measurement geometry peculiarities. The pull-back approach provides a significant improvement of measurement reproducibility and reduction of data deviation by 75-100%, resulting in a better discrimination between different histological groups.Type: ApplicationFiled: October 2, 2009Publication date: April 8, 2010Applicant: NOVADAQ TECHNOLOGIES INC.Inventors: Alexandre Douplik, Desmond C. Adler, Brian C. Wilson, Norman Marcon
-
Publication number: 20090303317Abstract: An endoscope or wand device comprising transmitting members, in which the transmitting members comprise a coating that transmits between about 95% and about 99.5% of energy at a wavelength within the infra red spectrum.Type: ApplicationFiled: February 7, 2007Publication date: December 10, 2009Applicant: Novadaq Technologies Inc.Inventor: John C. Tesar
-
Publication number: 20090285762Abstract: Disclosed herein are compositions and methods for imaging nerve cells. The composition comprises a fluorescent dye; and a viral component selected from a neurotropic, replication-defective virus, a viral protein of a neurotropic virus, and a capsid of a neurotropic virus. Although the fluorescent dye in itself cannot penetrate nerve cells, the fluorescent dye is bound to the viral component to form a dye/viral component complex that is capable of penetrating nerve cells.Type: ApplicationFiled: May 14, 2009Publication date: November 19, 2009Applicant: Novadaq Technologies Inc.Inventor: Robert W. Flower
-
Publication number: 20090203993Abstract: The invention provides methods and systems for imaging vessels in a subject. In certain embodiments the vessels may be associated with a solid organ transplant.Type: ApplicationFiled: April 26, 2006Publication date: August 13, 2009Applicant: Novadaq Technologies Inc.Inventors: Gurpreet Mangat, Lukasz Brzozowski, Richard L. Croft
-
Publication number: 20090203994Abstract: The invention provides methods and systems for neurovascular imaging (150).Type: ApplicationFiled: April 26, 2006Publication date: August 13, 2009Applicant: Novadaq Technologies Inc.Inventors: Gurpreet Mangat, Lukasz Brzozowski, Richard L. Croft
-
Publication number: 20080291397Abstract: The invention provides an apparatus, a device, and methods for imaging vasculature in a subject as well as an apparatus, a device and methods for treating abnormal vasculature in a subject.Type: ApplicationFiled: May 1, 2006Publication date: November 27, 2008Applicant: Novadaq Technologies Inc.Inventor: John C. Tesar
-
Publication number: 20080239070Abstract: An endoscopic video system and method using a camera with a single color image sensor, for example a CCD color image sensor, for fluorescence and color imaging and for simultaneously displaying the images acquired in these imaging modes at video rates in real time is disclosed. The tissue under investigation is illuminated continuously with fluorescence excitation light and is further illuminated periodically using visible light outside of the fluorescence excitation wavelength range. The illumination sources may be conventional lamps using filters and shutters, or may include light-emitting diodes mounted at the distal tip of the endoscope.Type: ApplicationFiled: December 26, 2007Publication date: October 2, 2008Applicant: Novadaq Technologies Inc.Inventors: Paul Westwick, David Potkins, John Fengler
-
Publication number: 20080228037Abstract: A fluorescence endoscopy video system includes a multimode light source that produces light for color and fluorescence imaging modes. Light from the light source is transmitted through an endoscope to the tissue under observation. The system also includes a compact camera for color and fluorescence imaging. Images obtained through the endoscope are optically divided and projected onto one or more image sensors by a fixed beam splitter in the camera. The fixed beam splitter eliminates the need for inserting a movable mirror into the light path between the endoscope and the image sensors. Image signals from the camera are processed in the system processor/controller where a contrast enhancement function can be applied. The contrast enhancement function increases the color contrast between normal tissue and tissue suspicious for early cancer. Finally, the system also includes a calibration feature whereby the system performance can be maintained when used with different endoscopes.Type: ApplicationFiled: January 7, 2008Publication date: September 18, 2008Applicant: Novadaq Technologies Inc.Inventors: Richard W. Cline, John J.P. Fengler, Joachim W. Boehm
-
Publication number: 20080221648Abstract: A method for treating a lesion of an animal, the animal having at least one vessel that carries blood to the lesion, comprising locating the vessel, administering a composition comprising a photodynamic agent, applying energy to the vessel to photocoagulate the vessel and thereby reduce the rate at which the treatment composition exits said lesion and applying energy to said lesion, of a type and an amount sufficient to excite the photodynamic agent, causing the lesion to undergo photodynamic therapy. Preferably, a dye that is both a fluorescent dye and a radiation absorbing dye, such as indocyanine green dye, is added to the treatment composition to allow (a) confirmation of the presence of the treatment composition b the lesion to be detected by fluorescent angiography and (b) the rate of blow flow to be reduced in the blood vessel feeding the lesion using dye enhanced photocoagulation.Type: ApplicationFiled: March 12, 2008Publication date: September 11, 2008Applicant: Novadaq Technologies Inc.Inventor: Robert Flower
-
Patent number: 7420151Abstract: A system for performing short wavelength imaging with a broadband illumination source includes an image processor that receives signals from a color image sensor. The image processor reduces the contribution of red illumination light to an image by computing blue, green, and blue-green (cyan) color components of display pixels from the signals received from the image sensor. The blue, green, and cyan color component values are coupled to inputs of a color monitor for display to produce a false color image of the tissue.Type: GrantFiled: October 10, 2006Date of Patent: September 2, 2008Assignee: Novadaq Technologies Inc.Inventors: John J. P. Fengler, Paul R. Westwick, Joachim W. Boehm
-
Publication number: 20080161744Abstract: The invention provides methods for pre- and intra-operatively localizing penile sentinel lymph nodes by injection of fluorescent dyes into penile tumors.Type: ApplicationFiled: September 6, 2007Publication date: July 3, 2008Applicants: University of Rochester Medical Center, Novadaq Technologies Inc.Inventors: Dragan Golijanin, Lukasz Brzozowski, Ronald Wood
-
Patent number: 7364574Abstract: A method for treating a lesion of an animal, the animal having at least one vessel that carries blood to the lesion, comprising locating the vessel, administering a composition comprising a photodynamic agent, applying energy to the vessel to photocoagulate the vessel and thereby reduce the rate at which the treatment composition exits said lesion and applying energy to said lesion, of a type and an amount sufficient to excite the photodynamic agent, causing the lesion to undergo photodynamic therapy. Preferably, a dye that is both a fluorescent dye and a radiation absorbing dye, such as indocyanine green dye, is added to the treatment composition to allow (a) confirmation of the presence of the treatment composition in the lesion to be detected by fluorescent angiography and (b) the rate of blow flow to be reduced in the blood vessel feeding the lesion using dye enhanced photocoagulation.Type: GrantFiled: July 16, 2003Date of Patent: April 29, 2008Assignee: Novadaq Technologies Inc.Inventor: Robert Flower
-
Patent number: 7341557Abstract: A fluorescence endoscopy video system includes a multimode light source that produces light for color and fluorescence imaging modes. Light from the light source is transmitted through an endoscope to the tissue under observation. The system also includes a compact camera for color and fluorescence imaging. Images obtained through the endoscope are optically divided and projected onto one or more image sensors by a fixed beam splitter in the camera. The fixed beam splitter eliminates the need for inserting a movable mirror into the light path between the endoscope and the image sensors. Image signals from the camera are processed in the system processor/controller where a contrast enhancement function can be applied. The contrast enhancement function increases the color contrast between normal tissue and tissue suspicious for early cancer. Finally, the system also includes a calibration feature whereby the system performance can be maintained when used with different endoscopes.Type: GrantFiled: July 26, 2004Date of Patent: March 11, 2008Assignee: Novadaq Technologies Inc.Inventors: Richard W. Cline, John J. P. Fengler, Joachim W. Boehm
-
Publication number: 20080027280Abstract: An applicator suitable for converting a white-light endoscope into an endoscope for combined white-light/fluorescence imaging is disclosed. The applicator facilitates attachment of an optical element, for example an optical filter, to a distal optical port of an endoscope. The applicator engages with alignment feature on the endoscope's distal end and releasably supports the optical element in an opening that is aligned with the optical port. The optical element is released in a proximal direction by pressing down on an actuator.Type: ApplicationFiled: July 30, 2007Publication date: January 31, 2008Applicant: Novadaq Technologies Inc.Inventors: John Fengler, John Senger, Gary Jenne
-
Publication number: 20060239921Abstract: The invention provides methods and systems for imaging vessels in a subject. In certain embodiments the vessels may be associated with a solid organ transplant.Type: ApplicationFiled: April 26, 2005Publication date: October 26, 2006Applicant: Novadaq Technologies Inc.Inventors: Gurpreet Mangat, Lukasz Brzozowski, Richard Croft