Patents Assigned to NovaSterilis Inc.
  • Patent number: 8974730
    Abstract: A process for creating acellular donor soft tissue by removing contaminants such as cells by extraction using a fluid at supercritical temperature and pressures while preserving the integrity of the soft tissue. The soft tissue is maintained in contact with the fluid in a pressure vessel at supercritical temperature and pressures for a period of time and then the pressure vessel is rapidly depressurized.
    Type: Grant
    Filed: October 6, 2011
    Date of Patent: March 10, 2015
    Assignee: Novasterilis, Inc.
    Inventors: David C. Burns, Anthony R. Eisenhut, Renee Christopher
  • Publication number: 20140193552
    Abstract: A method for sterilizing a ground meat product through the application supercritical CO2 during the processing of the meat by introducing supercritical CO2 into an extruder as the meat passes through the extruder while controlling the pressure and speed at which the meat passes through the extruder to maintain the meat in contact with the supercritical CO2 for a time sufficient achieve a log reduction in colony forming units of microbial contaminants.
    Type: Application
    Filed: January 10, 2013
    Publication date: July 10, 2014
    Applicant: Novasterilis, Inc.
    Inventors: David Burns, Thomas Steffie, Alecia Eppelsheimer
  • Patent number: 8658091
    Abstract: Treating absorbable sutures that have been sterilized using ethylene oxide with carbon dioxide at or near its supercritical pressure and temperature conditions to remove any residual ethylene oxide.
    Type: Grant
    Filed: September 15, 2011
    Date of Patent: February 25, 2014
    Assignee: Novasterilis, Inc.
    Inventors: David Burns, Anastasia J Nichols
  • Patent number: 8388944
    Abstract: Whole organisms are inactivated by at least a factor of 106 using carbon dioxide at or near its supercritical pressure and temperature conditions.
    Type: Grant
    Filed: September 23, 2010
    Date of Patent: March 5, 2013
    Assignee: Novasterilis Inc.
    Inventor: Tim W. Christensen
  • Patent number: 7919096
    Abstract: Whole organisms are inactivated by at least a factor of 106 using carbon dioxide at or near its supercritical pressure and temperature conditions.
    Type: Grant
    Filed: June 8, 2009
    Date of Patent: April 5, 2011
    Assignee: Novasterilis, Inc.
    Inventor: Tim W. Christensen
  • Patent number: 7771652
    Abstract: A method is disclosed that produces allografts from matrices typically containing demineralized bone matrix (DBM) powder, demineralized bone matrix gel, demineralized bone matrix paste, bone cement, cancellous bone, or cortical bone and mixtures thereof. The matrices are sterilized utilizing supercritical CO2 in the presence of a sterilizing additive and an entrainer such as an alkaline earth metal compound, preferably CaCO3. The resultant allograft materials have a reduced rate of rejection when used in allograft procedures including, bone, cartilage, tendon, and ligament grafting procedures.
    Type: Grant
    Filed: April 11, 2008
    Date of Patent: August 10, 2010
    Assignee: Novasterilis, Inc.
    Inventors: Renee A. Christopher, J. Anastasia Nichols
  • Patent number: 7108832
    Abstract: Sterilization methods and apparatus are effective to achieve a 6-log reduction in CFUs of industry standard bacteria and bacterial spores, i.e., B. stearothermophilus and B. subtilis spores, by subjecting sterilizable materials to a chemical additive-containing carbon dioxide sterilant fluid at or near its supercritical pressure and temperature conditions. Most preferably, the chemical additive-containing supercritical carbon dioxide sterilant fluid is agitated during sterilization, e.g., via mechanical agitation or via pressure cycling.
    Type: Grant
    Filed: June 17, 2004
    Date of Patent: September 19, 2006
    Assignee: NovaSterilis Inc.
    Inventors: Timothy Wayne Christensen, David Carroll Burns, Angela Lydia White, Bruce Ganem, Anthony Romey Eisenhut
  • Publication number: 20050025667
    Abstract: Sterilization methods and apparatus are effective to achieve a 6-log reduction in CFUs of industry standard bacteria and bacterial spores, i.e., B. stearothermophilus and B. subtilis spores, by subjecting sterilizable materials to a chemical additive-containing carbon dioxide sterilant fluid at or near its supercritical pressure and temperature conditions. Most preferably, the chemical additive-containing supercritical carbon dioxide sterilant fluid is agitated during sterilization, e.g., via mechanical agitation or via pressure cycling.
    Type: Application
    Filed: June 17, 2004
    Publication date: February 3, 2005
    Applicant: NovaSterilis Inc.
    Inventors: Timothy Christensen, David Burns, Angela White, Bruce Ganem, Anthony Eisenhut