Patents Assigned to Nycomed GmbH
  • Combination medicament
    Patent number: 7879833
    Abstract: The invention relates to the combination of ciclesonide with formoterol.
    Type: Grant
    Filed: December 11, 2003
    Date of Patent: February 1, 2011
    Assignee: NYCOMED GmbH
    Inventors: Christian Weimar, Klaus Dietzel, Helgert Müller, Degenhard Marx
  • Use of the combination of ciclesonide and antihistamines for the treatment of allergic rhinitis
    Patent number: 7879832
    Abstract: The present invention relates to a combination of ciclesonide with antihistamines.
    Type: Grant
    Filed: August 29, 2003
    Date of Patent: February 1, 2011
    Assignee: Nycomed GmbH
    Inventors: Degenhard Marx, Helgert Müller
  • PYRROLOPYRIMIDINECARBOXAMIDES
    Publication number: 20110021479
    Abstract: The compounds of Formula (I), in which R1, R21, R22, R23, R24, Y and R3 have the meanings as given in the description, the salts thereof, the N-oxides of the compounds and the salts thereof and the stereoisomers of the compounds, the salts, the N-oxides of the compounds and the N-oxides of the salts thereof are effective inhibitors of the type 5 phosphodiesterase.
    Type: Application
    Filed: February 25, 2009
    Publication date: January 27, 2011
    Applicant: NYCOMED GMBH
    Inventors: Josef Stadlwieser, Beate Schmidt, Heiko Bernsmann, Alexander Sudau, Torsten Dunkern, Degenhard Marx, Jörg Diefenbach
  • IMIDAZOPYRIDINE DERIVATIVES USEFUL AS INOS INHIBITORS
    Publication number: 20100317650
    Abstract: The compounds of formula (I) in which R1, R11 and A have the meanings as given in the description are novel effective iNOS inhibitors.
    Type: Application
    Filed: August 3, 2010
    Publication date: December 16, 2010
    Applicant: NYCOMED GmbH
    Inventors: Thomas FUCHSS, Andreas STRUB, Wolf-Rüdiger ULRICH, Christian HESSLINGER, Martin LEHNER, Raimund Külzer, Rainer BOER, Manfrid ELTZE
  • Triazolophthalazines
    Patent number: 7851472
    Abstract: The compounds of formula I in which R1 and R2 have the meanings as given in the description are novel effective PDE2 inhibitors.
    Type: Grant
    Filed: August 31, 2005
    Date of Patent: December 14, 2010
    Assignee: NYCOMED GmbH
    Inventors: Beate Schmidt, Steffen Weinbrenner, Dieter Flockerzi, Raimund Kuelzer, Hermann Tenor, Hans-Peter Kley
  • 3-oxa-10-aza-phenanthrenes
    Patent number: 7838521
    Abstract: The compounds of formula I in which R1, R2 and R3 have the meanings as given in the description, are novel effective PDE4 inhibitors.
    Type: Grant
    Filed: September 5, 2005
    Date of Patent: November 23, 2010
    Assignee: NYCOMED GmbH
    Inventors: Dieter Flockerzi, Ulrich Kautz, Armin Hatzelmann, Christof Zitt, Andrea Wohlsen, Degenhard Marx, Hans-Peter Kley, Jens Christoffers, Anna Rosiak
  • TRIAZOLOPHTHALAZINES
    Publication number: 20100286140
    Abstract: The compounds of formula I in which R1 and R2 have the meanings as given in the description are novel effective PDE2 inhibitors.
    Type: Application
    Filed: April 23, 2010
    Publication date: November 11, 2010
    Applicant: NYCOMED GMBH
    Inventors: Beate SCHMIDT, Steffen WEINBRENNER, Dieter FLOCKERZI, Raimund KUELZER, Hermann TENOR, Hans-Peter KLEY
  • 2-(piperidin-4-yl)-4,5-dihydro-2H-pyridazin-3-one derivatives as PDE4 inhibitors
    Patent number: 7820669
    Abstract: The compounds of a certain formula (1), in which R1, R2, R3 and R9 have the meanings as given in the description, are novel effective PDE4 inhibitors.
    Type: Grant
    Filed: January 14, 2009
    Date of Patent: October 26, 2010
    Assignee: NYCOMED GmbH
    Inventors: Wiro M. P. B. Menge, Geert Jan Sterk
  • STABILIZED PHARMACEUTICAL PRODUCT
    Publication number: 20100247585
    Abstract: Use of an adsorbent and a sealed package (e.g. an overwrap) to protect a pharmaceutical product in a solid state in the presence of a reducing sugar.
    Type: Application
    Filed: April 30, 2010
    Publication date: September 30, 2010
    Applicant: NYCOMED GMBH
    Inventors: Zoe HEATON, David GOODWIN, Iain BREAKWELL
  • COMPOSITION COMPRISING A PDE4 INHIBITOR AND A PDE5 INHIBITOR
    Publication number: 20100234382
    Abstract: The invention relates to the combined administration of a PDE4 inhibitor and a PDE5 inhibitor for the treatment of a disease in which phosphodiesterase 4 (PDE4) and/or phosphodiesterase 5 (PDE5) is detrimental.
    Type: Application
    Filed: May 24, 2010
    Publication date: September 16, 2010
    Applicant: NYCOMED GMBH
    Inventors: Torsten DUNKERN, Armin HATZELMANN, Christian SCHUDT, Friedrich GRIMMINGER, Hossein Ardeschir GHOFRANI
  • Preparation and administration form comprising an acid-labile active compound
    Patent number: 7794752
    Abstract: Novel administration forms and preparations for acid-labile active compounds are described. The novel administration forms contain individual active compound units, the active compound being present in the active compound units in a matrix made of a mixture comprising at least one fatty alcohol and at least one solid paraffin, in a matrix made of a mixture of a triglyceride and at least one solid paraffin or in a matrix made of a mixture comprising at least one fatty acid ester and at least one solid paraffin. In particular, the active compound units are microspheres which can be produced by prilling.
    Type: Grant
    Filed: May 31, 2000
    Date of Patent: September 14, 2010
    Assignee: NYCOMED GmbH
    Inventors: Rango Dietrich, Rudolf Linder
  • Preparation and administration form comprising an acid-labile active compound
    Patent number: 7790198
    Abstract: Novel administration forms and preparation for acid-labile active compounds are described. The novel administration forms contain individual active compound units, the active compound being present in the active compound units in a matrix made of a mixture comprising at least one fatty alcohol and at least one solid paraffin, in a matrix made of a mixture of a triglyceride and at least one solid paraffin or in a matrix made of a mixture comprising at least one fatty acid ester and at least one solid paraffin. In particular, the active compound units are microspheres which can be produced by prilling.
    Type: Grant
    Filed: February 9, 2006
    Date of Patent: September 7, 2010
    Assignee: NYCOMED GmbH
    Inventors: Rango Dietrich, Rudolf Linder
  • Imidazopyridine derivatives useful as iNOS inhibitors
    Patent number: 7790710
    Abstract: The compounds of formula (I) in which R1, R11 and A have the meanings as given in the description are novel effective iNOS inhibitors.
    Type: Grant
    Filed: March 29, 2006
    Date of Patent: September 7, 2010
    Assignee: NYCOMED GmbH
    Inventors: Thomas Fuchss, Andreas Strub, Wolf-Rüdiger Ulrich, Christian Hesslinger, Martin Lehner, Raimund Külzer, Rainer Boer, Manfrid Eltze
  • Preparation and administration form comprising an acid-labile active compound
    Patent number: 7785630
    Abstract: Novel administration forms and preparation for acid-labile active compounds are described. The novel administration forms contain individual active compound units, the active compound being present in the active compound units in a matrix made of a mixture comprising at least one fatty alcohol and at least one solid paraffin, in a matrix made of a mixture of a triglyceride and at least one solid paraffin or in a matrix made of a mixture comprising at least one fatty acid ester and at least one solid paraffin. In particular, the active compound units are microspheres which can be produced by prilling.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: August 31, 2010
    Assignee: NYCOMED GmbH
    Inventors: Rango Dietrich, Rudolf Linder
  • Use of PDE4 inhibitors for the treatment of diabetes mellitus
    Patent number: 7776893
    Abstract: The invention relates to the use of certain known PIDE4 inhibitors for the treatment of diabetes mellitus and accompanying disorders thereof.
    Type: Grant
    Filed: September 2, 2004
    Date of Patent: August 17, 2010
    Assignee: NYCOMED GmbH
    Inventor: Hans-Peter Kley
  • Novel salts of 6-heterocycle substituted hexahydrophenanthridine derivatives
    Publication number: 20100190818
    Abstract: The invention relates to salts of 6-heteroaryl substituted hexahydrophenanthridine PDE4 inhibiting compounds, which can be used in the pharmaceutical industry for the production of pharmaceutical composition for use, e.g., in treatment of airway disorders.
    Type: Application
    Filed: March 26, 2010
    Publication date: July 29, 2010
    Applicant: Nycomed GmbH
    Inventors: Ulrich Kautz, Matthias Webel, Christian Scheufler, Rolf-Peter Hummel
  • Novel use for PDE5 inhibitors
    Publication number: 20100179152
    Abstract: The present invention is concerned with the use of PDE5 inhibitors in medicine.
    Type: Application
    Filed: January 4, 2010
    Publication date: July 15, 2010
    Applicant: NYCOMED GmbH
    Inventors: Torsten Dunkern, Christian Schudt, Friedrich Grimminger, Hossein Ardeschir Ghofrani, Manfred Kaps, Bernhard Rosengarten
  • Combination treatment for diabetes mellitus
    Publication number: 20100179131
    Abstract: The invention relates to combinations of (2R,4aR,10bR)-6-(2,6-Dimethoxy-pyridin-3-yl)-9-ethoxy-8-methoxy-1,2,3,4,4a,10b-hexahydrophenanthridine-2-ol with other active compounds for the treatment of diabetes mellitus type 2 and/or type 1.
    Type: Application
    Filed: September 4, 2007
    Publication date: July 15, 2010
    Applicant: NYCOMED GMBH
    Inventors: Thomas Klein, Anja Blaser, Bettina Rudolph, Ulrich Kautz, Jens Selige, Wolfgang Kromer
  • Stabilized pharmaceutical product
    Patent number: 7736673
    Abstract: The invention relates to the use of an adsorbent and a sealed package, for example an overwrap, to protect a pharmaceutical product in a solid state in the presence of a reducing sugar.
    Type: Grant
    Filed: October 26, 2005
    Date of Patent: June 15, 2010
    Assignee: Nycomed GmbH
    Inventors: Zoe Heaton, David Goodwin, Iain Breakwell
  • Salts of 6-heterocycle substituted hexahydrophenanthridine derivatives
    Patent number: 7718668
    Abstract: The invention relates to salts of 6-heteroaryl substituted hexahydrophenanthridine PDE4-inhibiting compounds, which can be used in the pharmaceutical industry for the production of pharmaceutical compositions for use, e.g., in treatment of airway disorders.
    Type: Grant
    Filed: March 1, 2006
    Date of Patent: May 18, 2010
    Assignee: Nycomed GmbH
    Inventors: Ulrich Kautz, Matthias Webel, Christian Scheufler, Rolf-Peter Hummel