Patents Assigned to NYKEN HOLDING B.V.
  • Geranyl geranyl acetone analogs and uses thereof
    Patent number: 9688651
    Abstract: The invention relates to novel therapeutic compounds, more in particular to biologically active analogs and uses thereof as medicament, for instance for the treatment of atrial fibrillation. Provided is a compound of the general formula (formula I) wherein R1 is H or a saturated or unsaturated aliphatic moiety comprising 1 to 8 C-atoms; and X is selected from the group consisting of moieties X1, X2, X3, X4, X5 and X6. Exemplary uses include the prevention or therapeutic treatment of a HSF1-mediated disease.
    Type: Grant
    Filed: April 19, 2013
    Date of Patent: June 27, 2017
    Assignees: Nyken Holding B.V., Rijksuniversiteit Groningen, Academisch Ziekenhuis Groningen
    Inventors: Bianca Johanna Josephina Maria Brundel, Hermannus Steen, André Heeres, Johannes Paulus Gerardus Seerden
  • Geranyl Geranyl Acetone Analogs and Uses Thereof
    Publication number: 20150152076
    Abstract: The invention relates to novel therapeutic compounds, more in particular to biologically active analogs and uses thereof as medicament, for instance for the treatment of atrial fibrillation. Provided is a compound of the general formula (formula I) wherein R1 is H or a saturated or unsaturated aliphatic moiety comprising 1 to 8 C-atoms; and X is selected from the group consisting of moieties X1, X2, X3, X4, X5 and X6. Exemplary uses include the prevention or therapeutic treatment of a HSF1-mediated disease.
    Type: Application
    Filed: April 19, 2013
    Publication date: June 4, 2015
    Applicants: NYKEN HOLDING B.V., ACADEMISCH ZIEKENHUIS GRONINGEN, RIJKSUNIVERSITEIT GRONINGEN
    Inventors: Bianca Johanna Josephina Maria Brundel, Hermannus Steen, André Heeres, Johannes Paulus Gerardus Seerden