Abstract: The present invention discloses a new bionic lateral-line sensor. The new bionic lateral-line sensor includes a cilia cupule, a cilia base rod, IPMC film sheets, extraction electrodes, and a sensor housing. When external current acts on a free end of the cilia cupule, mechanical deformation is generated on the cilia cupule, and the mechanical deformation is transmitted to the cilia base rod, so as to cause deformation on the cilia base rod; the deformation on the cilia base rod leads to mechanical deformation on the IPMC film sheets, and the IPMC film sheets generate induced voltages by using an IPMC mechano-electric effect; and a flow rate of the external current is calculated according to the acquired induced voltages. The new bionic lateral-line sensor provided in the present invention is used for measurement of external current.

Abstract: A device for multi-parameter integrated monitoring of a deep submarine turbidity current primarily includes cement pile pore-pressure monitoring, optical turbidity monitoring, floating ball flow velocity monitoring, and turbidity current sediment sampling, can observe the turbidity, excess pore pressure, flow velocity, and other parameters of the turbidity current, can fulfill simultaneous and real-time transmission for in-situ monitoring, and can complete multiple tasks at the same observing position, so that the situation where the sampling position and the observing position are different due to the movement of an apparatus along with a ship during ordinary work is avoided.

Abstract: The present invention discloses a new bionic lateral-line sensor. The new bionic lateral-line sensor includes a cilia cupule, a cilia base rod, IPMC film sheets, extraction electrodes, and a sensor housing. When external current acts on a free end of the cilia cupule, mechanical deformation is generated on the cilia cupule, and the mechanical deformation is transmitted to the cilia base rod, so as to cause deformation on the cilia base rod; the deformation on the cilia base rod leads to mechanical deformation on the IPMC film sheets, and the IPMC film sheets generate induced voltages by using an IPMC mechano-electric effect; and a flow rate of the external current is calculated according to the acquired induced voltages. The new bionic lateral-line sensor provided in the present invention is used for measurement of external current.

Abstract: An observation system and determination method for the re-suspension quantity of submarine sediments by deep-sea internal waves. The observation system comprises a submarine observation platform, a mooring rope, and an anchor mooring counterweight. Acoustic release transponder, a single-point current meter, a turbidity meter, a high-precision temperature and salinity detector, and a sediment catcher are mounted on the submarine observation platform. A main floating body and auxiliary floating bodies are arranged on the mooring rope, wherein the main floating body is located in the middle of the mooring rope and is equipped with acoustic Doppler current profilers, and the auxiliary floating bodies are equipped with turbidity meters and high-precision temperature and salinity detectors. The anchor mooring counterweight is a gravity anchor provided with a square clamping groove and a fixed ring.

Abstract: The present invention provides alkaloids with formula I, II, III, IV, or V and their pharmaceutically acceptable salts, their preparation and their uses as antivirus drugs, for example, for treatment of HSV-1 infection. The alkaloids with formula I were isolated from the fermentation of marine fungus Scopulariopsis sp. (TA01-33) by means of column chromatography, such as positive phase silica gel column chromatography, etc. Alkaloids with formula II, III, IV and V were semisynthesized from compounds with formula I.

Abstract: An observation system and determination method for the re-suspension quantity of submarine sediments by deep-sea internal waves. The observation system comprises a submarine observation platform, a mooring rope, and an anchor mooring counterweight. Acoustic release transponder, a single-point current meter, a turbidity meter, a high-precision temperature and salinity detector, and a sediment catcher are mounted on the submarine observation platform. A main floating body and auxiliary floating bodies are arranged on the mooring rope, wherein the main floating body is located in the middle of the mooring rope and is equipped with acoustic Doppler current profilers, and the auxiliary floating bodies are equipped with turbidity meters and high-precision temperature and salinity detectors. The anchor mooring counterweight is a gravity anchor provided with a square clamping groove and a fixed ring.

Abstract: The present application relates to a method for selecting a wave height threshold, based on a target location, original wave height samples are acquired, and a wave height threshold interval are obtained; combined with wave height threshold and based on GPD and specified return period, a design wave height Hsi,j corresponding to each threshold within the wave height threshold interval is calculated according to the sample wave height values which are greater that the threshold; a difference is calculated to obtain a stable threshold interval, and a threshold within the stable threshold interval is selected as a reasonable threshold for design wave height estimation. In this method, the stability of estimated values can be determined directly and objectively to realize wave height threshold selection.

Abstract: Provided herein are quinolinone derivatives and their uses as antiviral drugs, for example, for treatment of HSV-1 infection. Also provided herein are pharmaceutically acceptable compositions comprising the quinolinone derivatives and the uses of the composition in the treatment of diseases caused by HSV-1 virus.

Abstract: A device for multi-parameter integrated monitoring of a deep submarine turbidity current primarily includes cement pile pore-pressure monitoring, optical turbidity monitoring, floating ball flow velocity monitoring, and turbidity current sediment sampling, can observe the turbidity, excess pore pressure, flow velocity, and other parameters of the turbidity current, can fulfill simultaneous and real-time transmission for in-situ monitoring, and can complete multiple tasks at the same observing position, so that the situation where the sampling position and the observing position are different due to the movement of an apparatus along with a ship during ordinary work is avoided.

Abstract: A device for observing the changes in abyssal flow based on differential pressure measurement, includes differential pressure sensing chamber and base connected through communicating portion, controller provided inside communicating portion, floating body and releasing device. Floating body is located on differential pressure sensing chamber and retracted through releasing device. Sensing chamber includes ambient water pressure chamber in communication with hydrostatic pressure chamber. Communicating portion is blocked by spring sheet. The spring sheet is provided with optical fiber sensor. Hydrostatic pressure chamber is always in communication with seawater, and ambient water pressure chamber is always in communication with water in abyssal sedimentary layer. Releasing device includes electric winch provided with acoustic signal device. Base is provided with earth pressure sensor and weight member. Optical fiber sensor, acoustic signal device, and earth pressure sensor are connected with controller.

Abstract: The invention provides an alginate oligosaccharide and its derivatives with the degree of polymerization ranging from 2 to 22. The alginate oligosaccharide is composed of ?-D-mannuronic acid linked by 1,4 glycosidic bonds. The derivatives with the reduced terminal in position 1 of carboxyl radical can be prepared by oxidative degradation. The invention also provides a process for preparing the alginate oligosaccharide and its derivatives, which includes the procedure that an alginate solution is reacted for 2 to 6 h in an autoclave at pH 2˜6 and the temperature of 100˜120° C., and adjusted pH to 7 after the reaction is stopped, after which the resultant oligosaccharide is oxidized in the presence of an oxidant to obtain an oxidative product. The alginate oligosaccharide and its derivatives of the invention can be used in the manufacture of a medicament for the prophylaxis and treatment of AD and diabetes.

Abstract: Disclosed is a lymph targeting nuclear magnetic contrast agent using a brown algae polysaccharide as a carrier, and a preparation method and a use thereof. A macromolecular contrast agent with good water solubility was prepared by using the brown algae polysaccharide as the carrier, using mannose or mannose derivatives as a mannose receptor (MBP) recognition group, and using a paramagnetic metal ion chelate as a nuclear magnetic resonance imaging group. The binding capacity of lymphoid tissue was improved. The mannose or mannose derivative group introduced into the synthesized contrast agent molecule achieves the goal of binding to the enriched mannose receptors in the lymphoid tissues.

Abstract: The invention relates to an oxygen and nitrogen co-doped polyacrylonitrile-based carbon fiber and a preparation method thereof. The oxygen and nitrogen co-doped polyacrylonitrile-based carbon fiber is prepared by electrochemical modification of a raw-material polyacrylonitrile-based carbon fiber, such that the surface thereof has an active layer formed by oxygen-containing active functional groups and nitrogen-containing active functional groups, wherein the nitrogen-containing active functional groups are obtained by activation of the doped nitrogen inherently contained in the raw-material polyacrylonitrile-based carbon fiber by means of electrochemical modification.

Abstract: The method for the measurement of turbulence by using reciprocating ocean microstructure profiler includes the following procedures: 1) system startup; 2) detection of the profile data of ocean dynamic environment information: a. temperature detection; b. shear detection; c. depth detection; and d. current and temperature & conductivity detection; e. gesture sensing; 3) control of ascending and descending operations of the profiler: a. uprising control; b. redirection operation; and c. sinking control; and 4) sleep mode. The method doesn't consume labor several times and the equipment is capable of providing long-time continuous profile measurement at a fixed area along a steel cable; and the entire system can ascend and descend steadily after hydrodynamic optimized layout, eliminating the measurement errors contributable to water flow fluctuation during detection, thus obtaining accurate ocean microstructure observation in vertical with higher precision.

Abstract: A reciprocating ocean microstructure profiler includes a first profiler subunit, a second profiler subunit and a central stand. The first profiler subunit is provided with the first buoyancy drive part and the first observation part; and the second profiler subunit is provided with the second buoyancy drive part and the second observation part. Both the first and second buoyancy drive parts are installed with a floating compartment, a drive compartment and a pressure housing each. A top oil bladder is provided in the floating compartment and a bottom oil bladder in the pressure housing. A drive pump assembly and a solenoid valve are installed in the drive compartment. The first and second observation parts are electrically connected to a controller each and each controller is electrically connected to a drive pump assembly and a solenoid valve.

Abstract: The invention provides an alginate oligosaccharide and its derivatives with the degree of polymerization ranging from 2 to 22. The alginate oligosaccharide is composed of ?-D-mannuronic acid linked by 1,4 glycosidic bonds. The derivatives with the reduced terminal in position 1 of carboxyl radical can be prepared by oxidative degradation. The invention also provides a process for preparing the alginate oligosaccharide and its derivatives, which includes the procedure that an alginate solution is reacted for 2 to 6 h in an autoclave at pH 2˜6 and the temperature of 100˜120° C., and adjusted pH to 7 after the reaction is stopped, after which the resultant oligosaccharide is oxidized in the presence of an oxidant to obtain an oxidative product. The alginate oligosaccharide and its derivatives of the invention can be used in the manufacture of a medicament for the prophylaxis and treatment of AD and diabetes.

Abstract: A selective breeding method of a new strain of Crassostrea gigas with orange left and right shells includes: selecting individuals of C. gigas with purple left shell and black mantle as the male broodstocks and individuals of C. gigas with black left shell and black mantle as the female broodstocks from cultured populations to generate a F1 family by applying single-pair mating strategy; selecting individuals with black purple left and right shells and black mantle from the F1 family as broodstocks to generate F2 families through family selection; selecting individuals with black purple left and right shells and black mantle from the F2 families as broodstocks to generate F3 families through family selection; and selecting individuals with orange left and right shells from the F3 families as broodstocks to propagate to generate a new strain of C. gigas with the stably inherited trait of orange left and right shells.

Abstract: A selective breeding method of a new strain of Crassostrea gigas with orange left and right shells, comprising the following steps: selecting individuals of C. gigas with purple left shell and black mantle as the male broodstocks and individuals of C. gigas with black left shell and black mantle as the female broodstocks from cultured populations to generate a F1 family by applying single-pair mating strategy; selecting individuals with black purple left and right shells and black mantle from the F1 family as broodstocks to generate F2 families through family selection; selecting individuals with black purple left and right shells and black mantle from the F2 families as broodstocks to generate F3 families through family selection; selecting individuals with orange left and right shells from the F3 families as broodstocks to propagate to generate a new strain of C. gigas with the stably inherited trait of orange left and right shells. The new color trait of C.

Abstract: An along-the-cable reciprocating motion control mechanism includes a moving platform, weight drop-off gear, weight release gear and trigger gear. The moving platform is set at a guide cable and can make reciprocating motion along the guide cable. A profiler is carried by the moving platform and the buoyancy of the moving platform carrying the profiler is greater than zero, the weight drop-off gear is set at the top of the guide cable and can drop a weight onto the moving platform within a predefined period, the weight release gear is provided on the moving platform, the trigger gear is set at the bottom of the guide cable, and when the moving platform carries a weight and descends to the bottom of the guide cable, the trigger gear touches the weight release gear to enable it to make a series of actions.

Abstract: An along-the-cable reciprocating motion control mechanism includes a moving platform, weight drop-off gear, weight release gear and trigger gear. The moving platform is set at a guide cable and can make reciprocating motion along the guide cable. A profiler is carried by the moving platform and the buoyancy of the moving platform carrying the profiler is greater than zero, the weight drop-off gear is set at the top of the guide cable and can drop a weight onto the moving platform within a predefined period, the weight release gear is provided on the moving platform, the trigger gear is set at the bottom of the guide cable, and when the moving platform carries a weight and descends to the bottom of the guide cable, the trigger gear touches the weight release gear to enable it to make a series of actions.