Abstract: The invention provides methods to exert antimicrobial effects in prophylactic or therapeutic treatment of bacterial or fungal infections employing polypeptides that have affinity to microbial and fungal toxins.
Abstract: The present invention relates to a group of peptidic compounds which have antimicrobial activity. The compounds also have affinity for toxins and especially for bacterial toxins, such as lipopolysaccharide or lipoteichoic acid. The compounds can be used to manufacture medicaments useful for the treatment of bacterial or fungal infections. The medicaments may be administered systemically or locally.