Abstract: The present invention relates to a method for culturing a 3-dimensional lung cancer organoid and a method for preparing a patient-derived xenograft animal model using the same. More specifically, the present invention relates to a method for culturing a 3-dimensional lung cancer organoid, a lung cancer organoid prepared by the method, a medium composition for culturing the lung cancer organoid, a method for preparing a xenograft animal model using the lung cancer organoid, a patient-derived lung cancer organoid xenograft animal model prepared by the method, and a method for analyzing therapeutic efficacy of an anticancer agent and a method for screening an anticancer agent, using the animal model.
Type:
Application
Filed:
December 8, 2023
Publication date:
April 4, 2024
Applicant:
ONCOCLEW CO., LTD.
Inventors:
Se Jin JANG, Min Suh KIM, Young Ah SUH, Hye Min MUN, Ju Hee OH
Abstract: The present invention relates to a method for culturing a 3-dimensional lung cancer organoid and a method for preparing a patient-derived xenograft animal model using the same. More specifically, the present invention relates to a method for culturing a 3-dimensional lung cancer organoid, a lung cancer organoid prepared by the method, a medium composition for culturing the lung cancer organoid, a method for preparing a xenograft animal model using the lung cancer organoid, a patient-derived lung cancer organoid xenograft animal model prepared by the method, and a method for analyzing therapeutic efficacy of an anticancer agent and a method for screening an anticancer agent, using the animal model.
Type:
Grant
Filed:
August 13, 2018
Date of Patent:
January 30, 2024
Assignee:
ONCOCLEW CO., LTD.
Inventors:
Se Jin Jang, Min Suh Kim, Young Ah Suh, Hye Min Mun, Ju Hee Oh