Patents Assigned to OptiScan Biomedical Corporation
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Publication number: 20130123592Abstract: Systems and methods for determining a physiological parameter in a patient are provided. In certain embodiments, a system can include an analyte detection system configured to measure first analyte data in a fluid sample received from a patient, a medical sensor configured to measure second analyte data in the patient, and a processor configured to receive the first analyte data and the second analyte data and to determine a physiological parameter based at least in part on the first analyte data and the second analyte data. In certain such embodiments, the medical sensor may be a pulse oximeter, and the physiological parameter may include a cardiovascular parameter including, for example, cardiac output.Type: ApplicationFiled: September 10, 2012Publication date: May 16, 2013Applicant: OPTISCAN BIOMEDICAL CORPORATIONInventor: Peter Rule
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Publication number: 20130114068Abstract: Systems and method are disclosed for determining a concentration of an analyte (e.g., glucose) in a fluid (e.g., blood). The system can draw blood from a patient and deliver the blood to a sample cell. A centrifuge motor can spin the sample cell to separate the fluid into a plurality of components (plasma, red blood cells, etc.). A particular component of the fluid (e.g., plasma) may be positioned at a sample portion of the sample cell after centrifuging such that the concentration of the analyte is measured in the particular component of the fluid (e.g., plasma). The sample cell can include a cuvette that has two window pieces sandwiched between two clamshell pieces, and where the sample portion of the sample cell is defined by a gap between the window pieces.Type: ApplicationFiled: July 5, 2012Publication date: May 9, 2013Applicant: OptiScan Biomedical CorporationInventors: Eugene Lim, Roger Tong
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Patent number: 8425444Abstract: Methods and apparatus are provided for determining the concentration of an analyte in a sample, such as an analyte in a sample of bodily fluid. In some embodiments, a method for maintaining clear passageways in an extracorporeal blood flow system includes intermittently providing one or more anti-clotting agents to a passageway of the extracorporeal blood flow system. In some embodiments, an extracorporeal blood flow system includes a passageway and a device operatively connected to provide one or more anti-clotting agents to a least a portion of said passageway.Type: GrantFiled: April 11, 2007Date of Patent: April 23, 2013Assignee: Optiscan Biomedical CorporationInventors: Richard Keenan, Jeff Chiou
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Patent number: 8417311Abstract: Disclosed are methods and apparatuses for determining analyte concentration in a sample such as bodily fluid. Systems and methods disclosed herein can also include a treatment dosing system to infuse or inject a treatment dose (e.g. insulin, dextrose, etc.) and provide glycemic control. The dose of the treatment drug may be based on the patient's calculated sensitivity to treatment dosing, for example. The dose of the treatment drug may be based on the concentration of the analyte or the average value for the concentration of the analyte and/or the rate of change of the value of the concentration of the analyte. Delivery of the treatment drug can be cut off if the determined analyte concentration indicates that continued delivery would be harmful to the patient.Type: GrantFiled: September 14, 2009Date of Patent: April 9, 2013Assignee: Optiscan Biomedical CorporationInventor: Peter Rule
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Patent number: 8412293Abstract: Systems and methods for determining a physiological parameter in a patient are provided. In certain embodiments, a system can include an analyte detection system configured to measure first analyte data in a fluid sample received from a patient, a medical sensor configured to measure second analyte data in the patient, and a processor configured to receive the first analyte data and the second analyte data and to determine a physiological parameter based at least in part on the first analyte data and the second analyte data. In certain such embodiments, the medical sensor may be a pulse oximeter, and the physiological parameter may include a cardiovascular parameter including, for example, cardiac output.Type: GrantFiled: July 16, 2008Date of Patent: April 2, 2013Assignee: Optiscan Biomedical CorporationInventor: Peter Rule
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Patent number: 8251907Abstract: In certain embodiments, a method of maintaining health of a patient uses an analyte detection system. The analyte detection system is coupled to the patient such that a bodily fluid of the patient is accessible to the analyte detection system. The method includes automatically initiating and conducting a measurement of an analyte in the bodily fluid using the analyte detection system. The method further includes determining a treatment dose for the patient based on the measurement using the analyte detection system.Type: GrantFiled: February 8, 2010Date of Patent: August 28, 2012Assignee: OptiScan Biomedical CorporationInventors: Bernhard B. Sterling, James R. Braig, Peter Rule, Richard A. King
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Patent number: 8197770Abstract: A fluid handling module is configured for removable engagement with a reusable main fluid handling instrument. The module includes a module housing and a first fluid passageway extending from the module housing. The first fluid passageway has a patient end remote from the housing. The first fluid passageway is configured to provide fluid communication with a bodily fluid in a patient. A fluid component separator is in fluid communication with the first fluid passageway. The fluid component separator is configured to separate at least one component from a portion of the bodily fluid drawn from the patient. A spectroscopic sample cell is configured to hold at least a portion of the first component.Type: GrantFiled: January 26, 2009Date of Patent: June 12, 2012Assignee: Optiscan Biomedical CorporationInventors: Jennifer H. Gable, James R. Braig, Kenneth I. Li, Mark Wechsler, Peng Zheng, Richard Keenan
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Patent number: 8139207Abstract: A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.Type: GrantFiled: August 15, 2011Date of Patent: March 20, 2012Assignee: OptiScan Biomedical CorporationInventors: James R. Braig, Peter Rule, Philip C. Hartstein, Bernhard B. Sterling, Jennifer H. Gable, Kenneth I. Li
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Patent number: 8140140Abstract: An apparatus for analyzing the composition of bodily fluid. The apparatus comprises a fluid handling network including a patient end configured to maintain fluid communication with a bodily fluid in a patient; and a pump unit in operative engagement with the fluid handling network. The pump unit has an infusion mode in which the pump unit is operable to deliver infusion fluid to the patient through the patient end, and a sample draw mode in which the pump unit is operable to draw a sample of the bodily fluid from the patient through the patient end. The apparatus further comprises a spectroscopic analyzer positioned to analyze at least a portion of the sample; a processor in communication with or incorporated into the spectroscopic analyzer; and stored program instructions executable by the processor to obtain measurements of two or more properties of the sample.Type: GrantFiled: December 21, 2005Date of Patent: March 20, 2012Assignee: OptiScan Biomedical CorporationInventors: Bernhard B. Sterling, James R. Braig, Kenneth G. Witte, Peter Rule, Richard Keenan, W. Dale Hall
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Publication number: 20110313318Abstract: Methods and systems for determining the concentration of one or more analytes from a sample such as blood or plasma are described. The systems described herein can be configured to withdraw a certain volume of sample from a source of bodily fluid, direct a first portion of the withdrawn sample to an analyte monitoring system and return a second portion of the sample to the patient. The analyte monitoring system can include an automated blood withdrawal system that is configured to withdraw blood from the patient's vasculature at low pressure and/or withdrawal rates so as to reduce or prevent contamination of the withdrawn fluid from the infusion fluids.Type: ApplicationFiled: June 16, 2011Publication date: December 22, 2011Applicant: OPTISCAN BIOMEDICAL CORPORATIONInventors: Peter Rule, James R. Braig, Richard Keenan, David N. Callicoat
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Publication number: 20110306856Abstract: Systems and methods for analyzing multiple components of a fluid sample are provided. In certain embodiments, a system can include an analyte detection system configured to measure first analyte data in a first component of a fluid sample received from a patient and measure second analyte data in a second component of a fluid sample. In some embodiments, one or more portions of an optical system is movable with respect to other portions of the system in order to optically and/or electrochemically analyze multiple components of a fluid sample. In other embodiments, optical and/or electrochemical analysis can be performed simultaneously on multiple components of a fluid sample. In some embodiments, a first analyte can be measured in a sample (e.g., whole blood) before the sample is separated into its components (e.g., plasma, red blood cells, etc.), and a second analyte can be measured in a component of the sample after separation.Type: ApplicationFiled: June 8, 2011Publication date: December 15, 2011Applicant: OptiScan Biomedical CorporationInventors: Peter Rule, James R. Braig, Richard Keenan, II, David Callicoat
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Publication number: 20110264071Abstract: Disclosed are methods and apparatus for determining analyte concentration in a sample such as bodily fluid. Systems and methods disclosed herein can also include a treatment dosing system to infuse or inject a treatment drug (e.g., insulin or glucose) and provide glycemic control. The dose of the treatment drug may be based on the concentration of the analyte or the average value for the concentration of the analyte and/or the rate of change of the value of the concentration of the analyte.Type: ApplicationFiled: June 30, 2011Publication date: October 27, 2011Applicant: OptiScan Biomedical CorporationInventors: James R. Braig, Richard Keenan, Peter Rule, Gil Rivas, Mahesh Seetharaman
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Patent number: 8034015Abstract: A method for maintaining clear passageways in an extracorporeal blood flow system. The method comprises intermittently providing one or more anti-clotting agents to a passageway of the extracorporeal blood flow system. Also disclosed is an extracorporeal blood flow system. The system comprises a passageway, and a device operatively connected to provide one or more anti-clotting agents to a least a portion of said passageway.Type: GrantFiled: April 28, 2008Date of Patent: October 11, 2011Assignee: OptiScan Biomedical CorporationInventors: James R. Braig, Richard Keenan
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Publication number: 20110218411Abstract: A fluid handling system for use in bodily fluid analysis. The system comprises a first fluid handling module configured to interface with a main instrument. The first fluid handling module has a first fluid handling network and the first fluid handling network includes an infusate passage and an infusion fluid pressure member suitable for moving fluid within the infusate passage. The fluid handling system also has a second fluid handling module separate from the first module which is configured to interface with the main instrument. The second fluid handling module has a second fluid handling network and at least one sample analysis cell which is accessible via the second fluid handling network. The first and second modules are configured to interconnect and provide fluid communication between the first and second fluid handling network and the sample cells.Type: ApplicationFiled: January 6, 2011Publication date: September 8, 2011Applicant: OptiScan Biomedical CorporationInventors: Richard Keenan, Jeff Chiou, Jennifer Gable, Ken Li, Roger Tong, Mike Recknor, James R. Braig
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Patent number: 7999927Abstract: A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.Type: GrantFiled: January 14, 2011Date of Patent: August 16, 2011Assignee: Optiscan Biomedical CorporationInventors: James R. Braig, Peter Rule, Philip C. Hartstein, Bernhard B. Sterling, Jennifer H. Gable, Kenneth I. Li
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Publication number: 20110190606Abstract: A fluid handling module that is removably engageable with a bodily fluid analyzer is provided. The module may comprise a fluid handling element, and a fluid component separator that is accessible via the fluid handling element and configured to separate at least one component of a bodily fluid transported to the fluid component separator. The fluid handling element may have at least one control element interface.Type: ApplicationFiled: March 11, 2011Publication date: August 4, 2011Applicant: OptiScan Biomedical CorporationInventors: Jennifer H. Gable, James R. Braig, Kenneth I. Li, Mark Wechsler, Peng Zheng, Richard Keenan
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Patent number: 7972296Abstract: Disclosed are methods and apparatus for determining analyte concentration in a sample such as bodily fluid. Systems and methods disclosed herein can also include a treatment dosing system to infuse or inject a treatment drug (e.g. insulin or glucose) and provide glycemic control. The dose of the treatment drug may be based on the concentration of the analyte or the average value for the concentration of the analyte and/or the rate of change of the value of the concentration of the analyte.Type: GrantFiled: October 10, 2008Date of Patent: July 5, 2011Assignee: OptiScan Biomedical CorporationInventors: James R. Braig, Richard Keenan, Peter Rule, Gil Rivas, Mahesh Seetharaman
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Publication number: 20110092784Abstract: Methods and systems for determining the concentration of one or more analytes from a sample such as blood or plasma are described. The systems described herein can be configured to withdraw a certain volume of sample from a source of bodily fluid, direct a first portion of the withdrawn sample to an analyte monitoring system and return a second portion of the sample to the patient. The analyte monitoring system can be connected to the source of bodily fluid via a connector that is configured to maintain uniform velocity across the connector and reduce the dead space volume.Type: ApplicationFiled: July 20, 2010Publication date: April 21, 2011Applicant: OptiScan Biomedical CorporationInventors: Michael Butler, Eugen Lim, Craig Johnson
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Patent number: 7907985Abstract: A fluid handling module that is removably engageable with a bodily fluid analyzer is provided. The module may comprise a fluid handling element, and a fluid component separator that is accessible via the fluid handling element and configured to separate at least one component of a bodily fluid transported to the fluid component separator. The fluid handling element may have at least one control element interface.Type: GrantFiled: December 21, 2005Date of Patent: March 15, 2011Assignee: Optiscan Biomedical CorporationInventors: Jennifer H. Gable, James R. Braig, Kenneth I. Li, Mark Wechsler, Peng Zheng, Richard Keenan
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Patent number: 7872734Abstract: A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.Type: GrantFiled: June 14, 2010Date of Patent: January 18, 2011Assignee: Optiscan Biomedical CorporationInventors: James R. Braig, Peter Rule, Phillip C. Hartstein, Bernhard B. Sterling, Jennifer H. Gable, Kenneth I. Li