Patents Assigned to Orca Biosystems, Inc.
  • Publication number: 20240075471
    Abstract: This disclosure provides methods and apparatuses for sorting target particles. In various embodiments, the disclosure provides a cassette for sorting target particles, methods for sorting target particles, methods of loading a microchannel for maintaining sample material viability, methods of quantifying sample material, and an optical apparatus for laser scanning and particle sorting.
    Type: Application
    Filed: August 4, 2023
    Publication date: March 7, 2024
    Applicant: Orca Biosystems, Inc.
    Inventors: Ivan K. Dimov, Nathaniel Fernhoff, Lagnajeet Pradhan
  • Patent number: 11759779
    Abstract: This disclosure provides methods and apparatuses for sorting target particles. In various embodiments, the disclosure provides a cassette for sorting target particles, methods for sorting target particles, methods of loading a microchannel for maintaining sample material viability, methods of quantifying sample material, and an optical apparatus for laser scanning and particle sorting.
    Type: Grant
    Filed: September 12, 2022
    Date of Patent: September 19, 2023
    Assignee: Orca Biosystems, Inc.
    Inventors: Ivan K. Dimov, Nathaniel Fernhoff, Lagnajeet Pradhan
  • Patent number: 11471885
    Abstract: This disclosure provides methods and apparatuses for sorting target particles. In various embodiments, the disclosure provides a cassette for sorting target particles, methods for sorting target particles, methods of loading a microchannel for maintaining sample material viability, methods of quantifying sample material, and an optical apparatus for laser scanning and particle sorting.
    Type: Grant
    Filed: June 16, 2020
    Date of Patent: October 18, 2022
    Assignee: Orca Biosystems, Inc.
    Inventors: Ivan K. Dimov, Nathaniel Fernhoff, Lagnajeet Pradhan
  • Patent number: 10857183
    Abstract: The present disclosure provides distinct therapeutic populations of cells that form a pharmaceutical composition useful in hematopoietic stem/progenitor cell transplant. For example, the present disclosure provides a therapeutic population of cells, comprising an enriched population of hematopoietic stem/progenitor cells, memory T cells, regulatory T cells, and wherein the population of cells is depleted of naïve conventional ??-T cells. The present disclosure further provides methods of treatment using the therapeutic population of cells. In other embodiments, the present disclosure provides methods of producing a therapeutic population of cells.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: December 8, 2020
    Assignee: ORCA BIOSYSTEMS, INC.
    Inventors: Ivan K. Dimov, Nathaniel Fernhoff, Kevin Sheehan
  • Patent number: 10722885
    Abstract: This disclosure provides methods and apparatuses for sorting target particles. In various embodiments, the disclosure provides a cassette for sorting target particles, methods for sorting target particles, methods of loading a microchannel for maintaining sample material viability, methods of quantifying sample material, and an optical apparatus for laser scanning and particle sorting.
    Type: Grant
    Filed: May 29, 2019
    Date of Patent: July 28, 2020
    Assignee: ORCA BIOSYSTEMS, INC.
    Inventors: Ivan K. Dimov, Nathaniel Fernhoff, Lagnajeet Pradhan
  • Patent number: 10350595
    Abstract: This disclosure provides methods and apparatuses for sorting target particles. In various embodiments, the disclosure provides a cassette for sorting target particles, methods for sorting target particles, methods of loading a microchannel for maintaining sample material viability, methods of quantifying sample material, and an optical apparatus for laser scanning and particle sorting.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: July 16, 2019
    Assignee: Orca Biosystems, Inc.
    Inventors: Ivan K. Dimov, Nathaniel Fernhoff, Lagnajeet Pradhan
  • Patent number: 10300090
    Abstract: The present disclosure provides distinct therapeutic populations of cells that form a pharmaceutical composition useful in hematopoietic stem/progenitor cell transplant. For example, the present disclosure provides a therapeutic population of cells, comprising an enriched population of hematopoietic stem/progenitor cells, memory T cells, regulatory T cells, and wherein the population of cells is depleted of naïve conventional ??-T cells. The present disclosure further provides methods of treatment using the therapeutic population of cells. In other embodiments, the present disclosure provides methods of producing a therapeutic population of cells.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: May 28, 2019
    Assignee: Orca Biosystems, Inc.
    Inventors: Ivan K. Dimov, Nathaniel Fernhoff, Kevin Sheehan