Abstract: Apparatus for transport of molecules including nucleic acid sequences in a bibulous carrier comprising a dry bibulous carrier defining a capillary transport path which supports the transport of the molecules when contacted with a solution containing the molecules.
Type:
Grant
Filed:
September 14, 1994
Date of Patent:
June 18, 1996
Assignee:
Orgenics Ltd.
Inventors:
Avraham Reinhartz, Sarah Alajem, Thierry Paper, Max Herzberg
Abstract: Apparatus for dry chemical analysis of fluids comprising a filter, a filter holder apparatus including a base member defining a filter supporting location and a filter retaining apparatus including a mesh arranged to retain the filter at the filter supporting location in spaced relationship with respect to the mesh.
Abstract: A method of assaying for the presence or quantity of a suspect nucleic acid in a suspect sample using a modified genetic probe in combination with an imaging procedure. The probe is modified by addition and provides an easy and very effective technique of modifying a genetic probe preparatory to its use in a kit. The genetic probe is then introduced into contact with DNA or RNA of the suspect sample and permitted to hybridize therewith. A kit for performing an assay using the modified probe is also disclosed.
Abstract: A stable chromogenic substrate mixture of indoxyl phosphate and tetrazolium salt is prepared by dissolving the phosphate in DMF and combining the same with Tris buffer containing magnesium chloride and followed by combination of the same with a DMF solution of tetrazolium salt. The resulting mixture is stored below room temperature in the absence of light.
Abstract: A method for assaying a specimen for the presence of a substance capable of inhibiting de novo biomolecular synthesis in a test microorganism, which comprises: exposing a cell wall permeability-enhanced test microorganism exhibiting delayed de novo synthesis of said biomolecule to said specimen, and assaying the extent of inhibition of synthesis of said biomolecule in said microorganism. A kit is described for performing the method, as well as a reaction mixture for performing the technique.
Abstract: A sheet for separating and retaining biological molecules. The sheet is activated with a compound for covalently binding a ligand to said sheet, and then coated with ligands having an affinity for the substance of interest. A method of using the sheet for isolating and separating substances of interest and methods for forming the sheet.