Patents Assigned to Orqis Medical Corporation
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Patent number: 7614997Abstract: An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment provides a vascular graft that has a first end that is sized and configured to couple to a non-primary blood vessel and a second end that is fluidly coupled to a pump to conduct blood between the pump and the non-primary blood vessel. An outflow conduit is also provided that has a first end sized and configured to be positioned within the same or different blood vessel, whether primary or non-primary, through the vascular graft. The outflow conduit is fluidly coupled to the pump to conduct blood between the pump and the patient. The vascular graft may be connected to the blood vessel subcutaneously to permit application of the extracardiac pumping system in a minimally-invasive procedure.Type: GrantFiled: May 3, 2006Date of Patent: November 10, 2009Assignee: Orqis Medical CorporationInventor: Steven F. Bolling
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Patent number: 7591778Abstract: An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment provides a vascular graft that has a first end that is sized and configured to couple to a non-primary blood vessel and a second end that is fluidly coupled to a pump to conduct blood between the pump and the non-primary blood vessel. An outflow conduit is also provided that has a first end sized and configured to be positioned within the same or different blood vessel, whether primary or non-primary, through the vascular graft. The outflow conduit is fluidly coupled to the pump to conduct blood between the pump and the patient. The vascular graft may be connected to the blood vessel subcutaneously to permit application of the extracardiac pumping system in a minimally-invasive procedure.Type: GrantFiled: May 3, 2006Date of Patent: September 22, 2009Assignee: Orqis Medical CorporationInventors: Steven F. Bolling, Anthony Viole, Shawn O'Leary
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Patent number: 7588531Abstract: An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment provides a vascular graft that has a first end that is sized and configured to couple to a non-primary blood vessel and a second end that is fluidly coupled to a pump to conduct blood between the pump and the non-primary blood vessel. An outflow conduit is also provided that has a first end sized and configured to be positioned within the same or different blood vessel, whether primary or non-primary, through the vascular graft. The outflow conduit is fluidly coupled to the pump to conduct blood between the pump and the patient. The vascular graft may be connected to the blood vessel subcutaneously to permit application of the extracardiac pumping system in a minimally-invasive procedure.Type: GrantFiled: May 3, 2006Date of Patent: September 15, 2009Assignee: Orqis Medical CorporationInventor: Steven F. Bolling
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Patent number: 7513863Abstract: An extracardiac pumping system and method for using it supplement the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart. A battery powered pump may be implanted subcutaneously and attached to an inflow conduit fluidly coupled to a patient's femoral artery via a subcutaneous anastomosis connection. The pump draws blood from the inflow conduit and discharges it through an outflow conduit fluidly coupled to a second peripheral artery via another subcutaneous anastomosis connection. The battery may be charged extracorporeally and the pump may be operated in either a continuous or pulsatile fashion in synchronization with the patient's heart. The conduits can be housed in a multi-lumen catheter and a reservoir may be provided which fluidly communicates with the inflow conduits. An additional feature may keep blood traveling extracorporeally within the system at or near body temperature.Type: GrantFiled: June 28, 2004Date of Patent: April 7, 2009Assignee: ORQIS Medical CorporationInventors: Steven F. Bolling, Morteza Gharib, Gabriel Aldea, Mary Lynn Gaddis, Anthony J. Viole
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Patent number: 7491163Abstract: A multilumen catheter that maximizes the blood flow into and out of the patient's vasculature while also providing for passive and/or active perfusion of tissue downstream of where the catheter resides in the vasculature. The inventive catheter comprises a proximal end, a first distal and a second distal end with first and second lumens extending from the proximal end to each of these distal ends to provide for blood circulation within one blood vessel or between two different blood vessels. The second lumen, and any additional lumens so desired, may be positioned coaxially with or radially around the first lumen. Redirecting means is provided at a distal end of at least one of said lumens for directing blood in a direction generally opposite of the direction of flow through said lumen.Type: GrantFiled: May 3, 2006Date of Patent: February 17, 2009Assignee: Orqis Medical CorporationInventors: Anthony Viole, Laksen Sirimanne, Steven F. Bolling, Shawn O'Leary, Robert Pecor, Ryan Kelly, Wolfgang Werner, Masoud Beizai
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Publication number: 20090043241Abstract: A connector system is provided for use in priming a fluid circuit. The system includes a first connector and a second connector. The first connector is configured to couple with one end of a conduit. The first connector has a gas permeable membrane, a main lumen extending from the gas permeable membrane, and a second lumen. The second lumen has a first end configured to couple with a fluid source and a second end in fluid communication with the main lumen. The second connector is configured to couple with an end of a cannula. The second connector has an end configured to be inserted through the gas permeable membrane into the first connector, whereby fluid communication can be established between the main lumen of the first connector and the cannula lumen.Type: ApplicationFiled: October 20, 2008Publication date: February 12, 2009Applicant: ORQIS MEDICAL CORPORATIONInventors: Robert Pecor, Michael Scott
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Patent number: 7458929Abstract: An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment provides a vascular graft that has a first end that is sized and configured to couple to a non-primary blood vessel and a second end that is fluidly coupled to a pump to conduct blood between the pump and the non-primary blood vessel. An outflow conduit is also provided that has a first end sized and configured to be positioned within the same or different blood vessel, whether primary or non-primary, through the vascular graft. The outflow conduit is fluidly coupled to the pump to conduct blood between the pump and the patient. The vascular graft may be connected to the blood vessel subcutaneously to permit application of the extracardiac pumping system in a minimally-invasive procedure.Type: GrantFiled: May 3, 2005Date of Patent: December 2, 2008Assignee: Orqis Medical CorporationInventors: Steven F. Bolling, Anthony Viole, Shawn O'Leary
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Patent number: 7445592Abstract: A percutaneous cannula is provided for the exchange of blood within a patient's vasculature. The cannula includes a main cannula portion and a tip portion. The main cannula portion comprises a proximal portion, a distal portion, a first lumen, and a second lumen extending through the proximal portion. The tip portion extends from the main cannula portion to a distal end of the cannula. The tip portion comprises a discharge opening and a redirecting member. The redirecting member is configured to direct blood flow being discharged through the discharge opening proximally along the cannula. At least one of the first and second lumens is configured to reduce the effect of flow resistance therein.Type: GrantFiled: June 10, 2004Date of Patent: November 4, 2008Assignee: Orqis Medical CorporationInventor: Robert Pecor
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Patent number: 7438699Abstract: A connector system is provided for use in priming a fluid circuit. The system includes a first connector and a second connector. The first connector is configured to couple with one end of a conduit. The first connector has a gas permeable membrane, a main lumen extending from the gas permeable membrane, and a second lumen. The second lumen has a first end configured to couple with a fluid source and a second end in fluid communication with the main lumen. The second connector is configured to couple with an end of a cannula. The second connector has an end configured to be inserted through the gas permeable membrane into the first connector, whereby fluid communication can be established between the main lumen of the first connector and the cannula lumen.Type: GrantFiled: March 6, 2006Date of Patent: October 21, 2008Assignee: Orqis Medical CorporationInventors: Robert Pecor, Michael Scott
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Patent number: 7331921Abstract: An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment of the intravascular extracardiac system comprises a pump with inflow and outflow conduits that are sized and configured to be implantable intravascularly through a non-primary vessel, whereby it may positioned where desired within the patient's vasculature. The system comprises a subcardiac pump that may be driven directly or electromagnetically from within or without the patient. The pump is configured to be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart.Type: GrantFiled: June 28, 2004Date of Patent: February 19, 2008Assignee: Orqis Medical CorporationInventors: Anthony Viole, Laksen Sirimanne, Steven F. Bolling, Shawn O'Leary, Robert Pecor, Ryan Kelly, Wolfgang Werner, Masoud Beizai
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Patent number: 7144365Abstract: An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and method of using same. One embodiment of the extracardiac system comprises a pump configured to be implanted subcutaneously in a minimally-invasive procedure, wherein the pump can draw blood through an inflow conduit, and can discharge blood through an outflow conduit. The pump may be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart. The conduits can be housed in a multi-lumen catheter.Type: GrantFiled: December 5, 2003Date of Patent: December 5, 2006Assignee: Orqis Medical CorporationInventors: Steven F. Bolling, Morteza Gharib, Gabriel Aldea, Mary Lynn Gaddis, Anthony J. Viole
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Patent number: 7125376Abstract: An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment of the intravascular extracardiac system comprises a pump with inflow and outflow conduits that are sized and configured to be implantable intravascularly through a non-primary vessel, whereby it may positioned where desired within the patient's vasculature. The system comprises a subcardiac pump that may be driven directly or electromagnetically from within or without the patient. The pump is configured to be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart.Type: GrantFiled: April 7, 2003Date of Patent: October 24, 2006Assignee: ORQIS Medical CorporationInventors: Anthony Viole, Laksen Sirimanne, Steven F. Bolling, Shawn O'Leary, Robert Pecor, Ryan Kelly, Wolfgang Werner, Masoud Beizai
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Patent number: 7048680Abstract: A multilumen catheter that maximizes the blood flow into and out of the patient's vasculature while also providing for passive and/or active perfusion of tissue downstream of where the catheter resides in the vasculature. The inventive catheter comprises a proximal end, a first distal and a second distal end. Lumens extending from the proximal end to each of these distal ends provide for blood circulation within one or between two blood vessels. At least one aperture in one of the lumens positioned near the proximal end provides for active perfusion of blood to the patient's vasculature downstream of where the aperture resides in the vasculature when the catheter is inserted into the patient for treatment. The inventive catheter may comprise a third lumen positioned entirely within the patient's vasculature, providing passive perfusion of blood to the patient's vasculature downstream of where the third lumen resides in the vasculature when the catheter is inserted into the patient for treatment.Type: GrantFiled: June 6, 2001Date of Patent: May 23, 2006Assignee: Orqis Medical CorporationInventors: Anthony Viole, Laksen Sirimanne, Steven F. Bolling, Shawn O'Leary, Wolfgang Werner
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Patent number: 6905481Abstract: The present invention is a percutaneous catheter assembly intended for long-term blood flow of several days, said assembly comprising generally three components: a catheter housing having three sections, each of preferably differing diameter, with a set of perforations in a distal section, an end cap for closing off a proximal end of the catheter housing during insertion, and a dilator having an outer diameter substantially the same size as the inner diameter of the smallest section of the catheter housing, the dilator being configured to pass radiopaque contrast through a first and second set of openings in the dilator and the perforations in the catheter housing. The present invention further comprises a method of percutaneous blood perfusion in which the catheter assembly is used without the need for an introducer sheath.Type: GrantFiled: December 2, 2002Date of Patent: June 14, 2005Assignee: Orqis Medical CorporationInventor: Laksen Sirimanne
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Patent number: 6889082Abstract: An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment provides a vascular graft that has a first end that is sized and configured to couple to a non-primary blood vessel and a second end that is fluidly coupled to a pump to conduct blood between the pump and the non-primary blood vessel. An outflow conduit is also provided that has a first end sized and configured to be positioned within the same or different blood vessel, whether primary or non-primary, through the vascular graft. The outflow conduit is fluidly coupled to the pump to conduct blood between the pump and the patient. The vascular graft may be connected to the blood vessel subcutaneously to permit application of the extracardiac pumping system in a minimally-invasive procedure.Type: GrantFiled: November 6, 2002Date of Patent: May 3, 2005Assignee: Orqis Medical CorporationInventors: Steven F. Bolling, Anthony Viole, Shawn O'Leary
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Patent number: 6761700Abstract: An extracorporeal vascular conduit for circulating blood outside a patient's body over an extended period of time in a manner that minimizes risk of thrombosis and complement activation and maximizes the ability of a patient to be ambulatory during recovery stages. The inventive vascular conduit comprises a first biocompatible material and a second synthetic material that is employed over a portion of the biocompatible material that extends outside the patient's body when is use. The majority of the portion that extends within the patient's body remains uncoated. A third synthetic material is applied around the conduit near the distal end of the second coating material of the catheter to permit a physician to secure the catheter to the patient's skin to minimize relative movement.Type: GrantFiled: February 9, 2001Date of Patent: July 13, 2004Assignee: Orqis Medical CorporationInventors: Laksen Sirimanne, Anthony Viole
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Patent number: 6610004Abstract: An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment of the intravascular extracardiac system comprises a pump with inflow and outflow conduits that are sized and configured to be implantable intravascularly through a non-primary vessel, whereby it may positioned where desired within the patient's vasculature. The system comprises a subcardiac pump that may be driven directly or electromagnetically from within or without the patient. The pump is configured to be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart.Type: GrantFiled: February 15, 2002Date of Patent: August 26, 2003Assignee: Orqis Medical CorporationInventors: Anthony Viole, Laksen Sirimanne, Steven F. Bolling, Shawn O'Leary, Robert Pecor, Ryan Kelly, Wolfgang Werner, Masoud Beizai
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Patent number: 6428464Abstract: An extracardiac pumping for supplementing the circulation of blood through a patient without any component thereof being connected to the patient's heart, and method of using same. The extracardiac system comprises a pump implanted subcutaneously at or about the patient's groin in a minimally-invasive procedure, wherein the pump is powered by a battery, and means for charging the battery extracorporeally, wherein the pump draws blood through an inflow conduit fluidly coupled to the patient's femoral artery via a subcutaneous anastomosis connection, and discharges blood through an outflow conduit fluidly coupled to a peripheral artery that stems from the patient's aortic arch via a subcutaneous anastomosis connection. The pump may be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the pumping load on the heart.Type: GrantFiled: April 9, 1999Date of Patent: August 6, 2002Assignee: Orqis Medical CorporationInventor: Steven F. Bolling
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Patent number: 6390969Abstract: An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and method of using same. One embodiment of the extracardiac system comprises an implantable or portable subcardiac pump, whereby the pump draws blood through an inflow conduit fluidly coupled to a non-primary artery via a cannula and discharges blood through an outflow conduit fluidly coupled to a second non-primary artery via a cannula, wherein at least one of the cannulas projects well into the patient's vascular system. The pump may be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart.Type: GrantFiled: April 21, 2000Date of Patent: May 21, 2002Assignee: Orqis Medical CorporationInventors: Steven F. Bolling, Morteza Gharib, Gabriel Aldea, Mary Lynn Gaddis, Anthony Viole
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Patent number: 6387037Abstract: An extracardiac pumping system and method for using it supplement the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart. A battery powered pump may be implanted subcutaneously and attached to an inflow conduit fluidly coupled to a patient's femoral artery via a subcutaneous anastomosis connection. The pump draws blood from the inflow conduit and discharges it through an outflow conduit fluidly coupled to a second peripheral artery via another subcutaneous anastomosis connection. The battery may be charged extracorporeally and the pump may be operated in either a continuous or pulsatile fashion in synchronization with the patient's heart. The conduits can be housed in a multi-lumen catheter and a reservoir may be provided which fluidly communicates with the inflow conduits. An additional feature may keep blood traveling extracorporeally within the system at or near body temperature.Type: GrantFiled: December 23, 1999Date of Patent: May 14, 2002Assignee: Orqis Medical CorporationInventors: Steven F. Bolling, Morteza Gharib, Gabriel Aldea, Mary Lynn Gaddis, Anthony J. Viole