Abstract: The invention relates generally to methods and apparatus for conducting analyses, particularly microfluidic devices for the detection of target analytes.
Abstract: The invention relates generally to methods and apparatus for conducting analyses, particularly microfluidic devices for the detection of target analytes.
Abstract: The invention relates to fluidics as used in medical and diagnostic equipment and relates further to means for purifying, abstracting, filtering, detecting and/or measuring analytes in liquid samples.
Type:
Grant
Filed:
July 17, 2012
Date of Patent:
July 21, 2015
Assignee:
OSMETECH TECHNOLOGY, INC.
Inventors:
Charles E Clemens, Robert Mucic, Rudolph A. Montalvo, Clark Foster, Gary R. Gust, Thomas P. Robinson, Gary T. Olsen
Abstract: The invention relates to the use of particles comprising binding ligands and electron transfer moieties (ETMs). Upon binding of a target analyte, a particle and a reporter composition are associated and transported to an electrode surface. The ETMs are then detected, allowing the presence or absence of the target analyte to be determined.
Abstract: The invention relates to the use of particles comprising binding ligands and electron transfer moieties (ETMs). Upon binding of a target analyte, a particle and a reporter composition are associated and transported to an electrode surface. The ETMs are then detected, allowing the presence or absence of the target analyte to be determined.
Abstract: The invention relates to the use of particles comprising binding ligands and electron transfer moieties (ETMs). Upon binding of a target analyte, a particle and a reporter composition are associated and transported to an electrode surface. The ETMs are then detected, allowing the presence or absence of the target analyte to be determined.
Abstract: The present invention is directed to methods and compositions for the use of self-assembled monolayers to electronically detect nucleic acids, particularly alterations such as nucleotide substitutions (mismatches) and single nucleotide polymorphisms (SNPs).
Type:
Grant
Filed:
July 26, 2000
Date of Patent:
May 3, 2011
Assignee:
Osmetech Technology Inc.
Inventors:
Robert M. Umek, Gary Blackburn, Bruce D. Irvine, Robert H. Terbrueggen, Changjun Yu, Jost G. Vielmetter
Abstract: The invention relates to fluidics as used in medical and diagnostic equipment and relates further to means for purifying, abstracting, filtering, detecting and/or measuring analytes in liquid samples.
Type:
Grant
Filed:
February 15, 2008
Date of Patent:
January 4, 2011
Assignee:
Osmetech Technology Inc.
Inventors:
Charles E. Clemens, Robert Mucic, Rudolph A. Montalvo, Clark Foster, Gary R. Gust, Thomas P. Robinson, Gary T. Olsen
Abstract: The invention relates to novel methods and compositions for the detection of analytes using the nuclear reorganization energy, ?, of an electron transfer process.
Abstract: The invention relates to compositions and methods useful in the acceleration of binding of target analytes to capture ligands on surfaces. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the target analyte, either directly or indirectly, to allow electronic detection of the ETM.
Type:
Grant
Filed:
April 12, 2004
Date of Patent:
February 2, 2010
Assignee:
Osmetech Technology Inc.
Inventors:
Gary Blackburn, Stephen E. Creager, Scott Fraser, Bruce D. Irvine, Thomas J. Meade, Stephen J. O'Connor, Robert H. Terbrueggen, Jost G. Vielmetter, Thomas W. Welch
Abstract: The invention relates to fluidics as used in medical and diagnostic equipment and relates further to means for purifying, abstracting, filtering, detecting and/or measuring analytes in liquid samples.
Type:
Application
Filed:
August 3, 2009
Publication date:
November 26, 2009
Applicant:
Osmetech Technology Inc.
Inventors:
Charles E. Clemmens, Robert Mucic, Rudolph A. Montalvo, Clark Foster, Gary R. Gust, Thomas P. Robinson, Gary T. Olsen
Abstract: The invention relates to novel methods and compositions for the detection of analytes using the nuclear reorganization energy, ?, of an electron transfer process.
Abstract: The invention relates to novel methods and compositions for the detection of analytes using the nuclear reorganization energy, ?, of an electron transfer process.