Patents Assigned to OsteoSA Inc.
  • Use of fibroblast growth factors to stimulate bone growth
    Patent number: 5656598
    Abstract: The present invention provides therapeutic compositions for the prevention and treatment of pathological conditions involving bone and dental tissue. The present invention also provides a method to promote bone repair and/or growth for the treatment of pathological conditions involving bone tissue, for example, osteoporosis, Paget's disease, osteopetrosis, and periodontal disease and fracture repair, and healing of bone defects by administering FGF-1 to an animal or human in need of such treatment.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: August 12, 1997
    Assignees: Rhone-Poulenc Rorer Pharmaceuticals Inc., Osteosa Inc.
    Inventors: Colin R. Dunstan, Elzbieta Izbicka, Gregory R. Mundy, Wilson Burgess, Michael C. Jaye
  • Use of fibroblast growth factors to stimulate bone growth
    Patent number: 5614496
    Abstract: The present invention provides therapeutic compositions for the prevention and treatment of pathological conditions involving bone and dental tissue. The present invention also provides a method to promote bone repair and/or growth for the treatment of pathological conditions involving bone tissue, for example, osteoporosis, Paget's disease, osteopetrosis, and periodontal disease and fracture repair, and healing of bone defects by administering FGF-1 to an animal or human in need of treatment.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: March 25, 1997
    Assignees: OsteoSA Inc., Rhone-Poulenc Rorer Pharmaceuticals Inc.
    Inventors: Colin R. Dunstan, Elzbieta Izbicka, Gregory R. Mundy, Wilson Burgess, Michael C. Jaye
  • Process of purifying antler-derived bone growth factors
    Patent number: 5408041
    Abstract: The present invention relates to the development of bone growth factors as therapeutics for the prevention and treatment of pathological conditions involving bone tissue. The present invention provides biologically active proteinaceous factors comprising polypeptides containing the amino acid sequence M-A-G-L-G-D-E-F-G-D, [SEQ ID NO: 1], (X) F E T L F G A/V E D V I/D A L Q F V C G D, [SEQ ID NO: 2], or A-Y-I-P-I-E-T-L-E-G-I/G-E-L-V-D/Q-T-G/L-Q-F, [SEQ ID NO: 3], or biologically active fragments or sequence analogues thereof. Among the biological properties of the proteinaceous materials of the present invention is the capability to promote the growth and/or differentiation of osteoblastic cells.
    Type: Grant
    Filed: January 13, 1994
    Date of Patent: April 18, 1995
    Assignees: Rhone-Poulenc Rorer Pharmaceuticals Inc., OsteoSA Inc.
    Inventors: Gregory R. Mundy, Gloria E. Gutierrez, Ian R. Garrett, Massimo Sabatini, Elzbieta Izbicka, Wilson Burgess, Gregg R. Crumley, Clarence C. Morse, Timothy R. Arnett