Patents Assigned to PARTICLE DYNAMICS INTERNATIONAL, LLC
  • Patent number: 11154570
    Abstract: The present invention generally relates to iron-polysaccharide (polydextrose) complexes and methods for the preparation thereof. In particular, the present invention relates to iron-polydextrose complexes and methods for the preparation thereof. The inventive complexes are suitable for use in various compositions, including particulate compositions that may be incorporated in various forms of administration, including tablets, capsules, and intravenous formulations. The complexes and compositions of the present invention are suitable for use in the treatment of iron deficient anemia. Advantageously, in addition to providing iron supplementation the complexes and compositions of the present invention provide certain advantages based on the presence of polydextrose (e.g., its low glycemic index and high fiber content).
    Type: Grant
    Filed: April 28, 2020
    Date of Patent: October 26, 2021
    Assignee: Particle Dynamics International, LLC.
    Inventors: Paul Brady, Keith Cromack
  • Publication number: 20200345765
    Abstract: The present invention generally relates to iron-polysaccharide (polydextrose) complexes and methods for the preparation thereof. In particular, the present invention relates to iron-polydextrose complexes and methods for the preparation thereof. The inventive complexes are suitable for use in various compositions, including particulate compositions that may be incorporated in various forms of administration, including tablets, capsules, and intravenous formulations. The complexes and compositions of the present invention are suitable for use in the treatment of iron deficient anemia. Advantageously, in addition to providing iron supplementation the complexes and compositions of the present invention provide certain advantages based on the presence of polydextrose (e.g., its low glycemic index and high fiber content).
    Type: Application
    Filed: April 28, 2020
    Publication date: November 5, 2020
    Applicant: Particle Dynamics International, LLC
    Inventors: Paul Brady, Keith Cromack
  • Patent number: 10682375
    Abstract: The present invention generally relates to iron-polysaccharide (polydextrose) complexes and methods for the preparation thereof. In particular, the present invention relates to iron-polydextrose complexes and methods for the preparation thereof. The inventive complexes are suitable for use in various compositions, including particulate compositions that may be incorporated in various forms of administration, including tablets, capsules, and intravenous formulations. The complexes and compositions of the present invention are suitable for use in the treatment of iron deficient anemia. Advantageously, in addition to providing iron supplementation the complexes and compositions of the present invention provide certain advantages based on the presence of polydextrose (e.g., its low glycemic index and high fiber content).
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: June 16, 2020
    Assignee: Particle Dynamics International, LLC
    Inventors: Paul Brady, Keith Cromack
  • Publication number: 20200170291
    Abstract: The present invention is generally directed to processes for producing lactitol granulates. The present invention is also directed to lactitol granulates exhibiting one or more desirable and improved properties as compared to prior lactitol granulates.
    Type: Application
    Filed: May 22, 2018
    Publication date: June 4, 2020
    Applicant: PARTICLE DYNAMICS INTERNATIONAL, LLC
    Inventors: Keith Cromack, Steve Freebersyser, Paul Brady
  • Patent number: 10258647
    Abstract: The present invention generally relates to iron-polysaccharide (polydextrose) complexes and methods for the preparation thereof. In particular, the present invention relates to iron-polydextrose complexes and methods for the preparation thereof. The inventive complexes are suitable for use in various compositions, including particulate compositions that may be incorporated in various forms of administration, including tablets, capsules, and intravenous formulations. The complexes and compositions of the present invention are suitable for use in the treatment of iron deficient anemia. Advantageously, in addition to providing iron supplementation the complexes and compositions of the present invention provide certain advantages based on the presence of polydextrose (e.g., its low glycemic index and high fiber content).
    Type: Grant
    Filed: August 30, 2016
    Date of Patent: April 16, 2019
    Assignee: PARTICLE DYNAMICS INTERNATIONAL, LLC
    Inventors: Paul Brady, Keith Cromack
  • Publication number: 20190022138
    Abstract: The present invention generally relates to iron-polysaccharide (polydextrose) complexes and methods for the preparation thereof. In particular, the present invention relates to iron-polydextrose complexes and methods for the preparation thereof. The inventive complexes are suitable for use in various compositions, including particulate compositions that may be incorporated in various forms of administration, including tablets, capsules, and intravenous formulations. The complexes and compositions of the present invention are suitable for use in the treatment of iron deficient anemia. Advantageously, in addition to providing iron supplementation the complexes and compositions of the present invention provide certain advantages based on the presence of polydextrose (e.g., its low glycemic index and high fiber content).
    Type: Application
    Filed: September 24, 2018
    Publication date: January 24, 2019
    Applicant: Particle Dynamics International, LLC
    Inventors: Paul Brady, Keith Cromack
  • Publication number: 20170216224
    Abstract: The present invention generally relates to improvements in the bioavailability and/or solubility of coenzyme Q10. For example, the present invention relates to methods for preparing particulate compositions including coenzyme Q10 that generally comprise dispersing and/or dissolving the coenzyme Q10 throughout a suitable solvent, and combining the coenzyme Q10 and an encapsulating (e.g., microencapsulating) agent. The present invention also generally relates to particulate compositions comprising coenzyme Q10 that exhibit improved bioavailability and/or solubility as compared to previous coenzyme Q10 products.
    Type: Application
    Filed: April 20, 2017
    Publication date: August 3, 2017
    Applicant: PARTICLE DYNAMICS INTERNATIONAL, LLC
    Inventor: Irwin C. Jacobs
  • Patent number: 9655849
    Abstract: The present invention generally relates to improvements in the bioavailability and/or solubility of coenzyme Q10. For example, the present invention relates to methods for preparing particulate compositions including coenzyme Q10 that generally comprise dispersing and/or dissolving the coenzyme Q10 throughout a suitable solvent, and combining the coenzyme Q10 and an encapsulating (e.g., microencapsulating) agent. The present invention also generally relates to particulate compositions comprising coenzyme Q10 that exhibit improved bioavailability and/or solubility as compared to previous coenzyme Q10 products.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: May 23, 2017
    Assignee: Particle Dynamics International, LLC
    Inventor: Irwin C. Jacobs
  • Publication number: 20170056444
    Abstract: The present invention generally relates to iron-polysaccharide (polydextrose) complexes and methods for the preparation thereof. In particular, the present invention relates to iron-polydextrose complexes and methods for the preparation thereof. The inventive complexes are suitable for use in various compositions, including particulate compositions that may be incorporated in various forms of administration, including tablets, capsules, and intravenous formulations. The complexes and compositions of the present invention are suitable for use in the treatment of iron deficient anemia. Advantageously, in addition to providing iron supplementation the complexes and compositions of the present invention provide certain advantages based on the presence of polydextrose (e.g., its low glycemic index and high fiber content).
    Type: Application
    Filed: August 30, 2016
    Publication date: March 2, 2017
    Applicant: Particle Dynamics International, LLC
    Inventors: Paul Brady, Keith Cromack
  • Publication number: 20160374942
    Abstract: The present invention generally relates to dosage forms for oral administration including one or more gelling agents. In particular, the present invention is directed to gelling agent-based dosage forms that are easily administered and taken, or swallowed. The present invention is also directed to gelling agent-based dosage forms that exhibit relatively low syneresis, are thermally stable, exhibit substantially constant active ingredient concentration, and/or exhibit one or more advantageous rheological properties. In particular, the present invention is directed to such gels containing one or more omega-3 fatty acids. The gelling agent-based dosage forms of the present invention are suitable for administration of a relatively large dose of active ingredient. The gelling agent-based dosage forms of the present invention are also suitable for administration of multiple active ingredients.
    Type: Application
    Filed: August 16, 2016
    Publication date: December 29, 2016
    Applicant: PARTICLE DYNAMICS INTERNATIONAL, LLC
    Inventors: Irwin Jacobs, Stephen Gee, Paul Brady
  • Patent number: 9452135
    Abstract: The present invention generally relates to dosage forms for oral administration including one or more gelling agents. In particular, the present invention is directed to gelling agent-based dosage forms that are easily administered and taken, or swallowed. The present invention is also directed to gelling agent-based dosage forms that exhibit relatively low syneresis, are thermally stable, exhibit substantially constant active ingredient concentration, and/or exhibit one or more advantageous rheological properties. In particular, the present invention is directed to such gels containing one or more omega-3 fatty acids. The gelling agent-based dosage forms of the present invention are suitable for administration of a relatively large dose of active ingredient. The gelling agent-based dosage forms of the present invention are also suitable for administration of multiple active ingredients.
    Type: Grant
    Filed: March 19, 2013
    Date of Patent: September 27, 2016
    Assignee: Particle Dynamics International, LLC
    Inventors: Irwin Jacobs, Stephen Gee, Paul Brady
  • Patent number: 9339475
    Abstract: The present invention relates to spatially arranging a plurality of particles in a device for the oral delivery of a pharmaceutical. In particular, the plurality of particles is utilized for the oral delivery of a pharmaceutical to a subject via the drinking device.
    Type: Grant
    Filed: February 3, 2014
    Date of Patent: May 17, 2016
    Assignee: Particle Dynamics International, LLC
    Inventors: Jonathan David Bortz, Yury Lagoviyer, Paul Timothy Brady
  • Publication number: 20150140113
    Abstract: The present invention generally relates to dosage forms for oral administration including one or more gelling agents. In particular, the present invention is directed to gelling agent-based dosage forms that are easily administered and taken, or swallowed. The present invention is also directed to gelling agent-based dosage forms that exhibit relatively low syneresis, are thermally stable, exhibit substantially constant active ingredient concentration, and/or exhibit one or more advantageous rheological properties. In particular, the present invention is directed to such gels containing one or more omega-3 fatty acids. The gelling agent-based dosage forms of the present invention are suitable for administration of a relatively large dose of active ingredient. The gelling agent-based dosage forms of the present invention are also suitable for administration of multiple active ingredients.
    Type: Application
    Filed: March 19, 2013
    Publication date: May 21, 2015
    Applicant: PARTICLE DYNAMICS INTERNATIONAL, LLC
    Inventors: Irwin Jacobs, Stephen Gee, Paul Brady
  • Patent number: 8859011
    Abstract: Compositions comprising calcium carbonate and processes for making such compositions are provided. The invention provides a granulation comprising about 95% to about 99% by weight calcium carbonate, about 0.5% to about 5% by weight of a binder and about 0.03% to about 3% by weight of a porosity increasing agent. A pharmaceutical or nutritional composition prepared from such a granulation comprises about 90% to about 99% by weight calcium carbonate, about 0.03% to about 3% by weight of a porosity increasing agent, and about 1% to about 10% by weight of other excipients. The composition provides a smaller tablet than conventional calcium carbonate compositions, for improved ease of swallowing.
    Type: Grant
    Filed: May 10, 2007
    Date of Patent: October 14, 2014
    Assignee: Particle Dynamics International, LLC
    Inventors: Denis Stotler, Steven R. Freebersyser, R. Saul Levinson
  • Publication number: 20140212505
    Abstract: The present invention relates to spatially arranging a plurality of particles in a device for the oral delivery of a pharmaceutical. In particular, the plurality of particles is utilized for the oral delivery of a pharmaceutical to a subject via the drinking device.
    Type: Application
    Filed: February 3, 2014
    Publication date: July 31, 2014
    Applicant: Particle Dynamics International, LLC
    Inventors: Jonathan David Bortz, Yury Lagoviyer, Paul Timothy Brady
  • Patent number: 8679541
    Abstract: The present invention relates to spatially arranging a plurality of particles in a device for the oral delivery of a pharmaceutical. In particular, the plurality of particles is utilized for the oral delivery of a pharmaceutical to a subject via the drinking device.
    Type: Grant
    Filed: February 18, 2008
    Date of Patent: March 25, 2014
    Assignee: Particle Dynamics International, LLC
    Inventors: Jonathan David Bortz, Yury Lagoviyer, Paul Timothy Brady
  • Publication number: 20130330408
    Abstract: The present invention generally relates to improvements in the bioavailability and/or solubility of coenzyme Q10. For example, the present invention relates to methods for preparing particulate compositions including coenzyme Q10 that generally comprise dispersing and/or dissolving the coenzyme Q10 throughout a suitable solvent, and combining the coenzyme Q10 and an encapsulating (e.g., microencapsulating) agent. The present invention also generally relates to particulate compositions comprising coenzyme Q10 that exhibit improved bioavailability and/or solubility as compared to previous coenzyme Q10 products.
    Type: Application
    Filed: March 16, 2012
    Publication date: December 12, 2013
    Applicant: PARTICLE DYNAMICS INTERNATIONAL, LLC
    Inventor: Irwin C. Jacobs