Patents Assigned to PARTICLE DYNAMICS INTERNATIONAL, LLC
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Patent number: 11154570Abstract: The present invention generally relates to iron-polysaccharide (polydextrose) complexes and methods for the preparation thereof. In particular, the present invention relates to iron-polydextrose complexes and methods for the preparation thereof. The inventive complexes are suitable for use in various compositions, including particulate compositions that may be incorporated in various forms of administration, including tablets, capsules, and intravenous formulations. The complexes and compositions of the present invention are suitable for use in the treatment of iron deficient anemia. Advantageously, in addition to providing iron supplementation the complexes and compositions of the present invention provide certain advantages based on the presence of polydextrose (e.g., its low glycemic index and high fiber content).Type: GrantFiled: April 28, 2020Date of Patent: October 26, 2021Assignee: Particle Dynamics International, LLC.Inventors: Paul Brady, Keith Cromack
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Publication number: 20200345765Abstract: The present invention generally relates to iron-polysaccharide (polydextrose) complexes and methods for the preparation thereof. In particular, the present invention relates to iron-polydextrose complexes and methods for the preparation thereof. The inventive complexes are suitable for use in various compositions, including particulate compositions that may be incorporated in various forms of administration, including tablets, capsules, and intravenous formulations. The complexes and compositions of the present invention are suitable for use in the treatment of iron deficient anemia. Advantageously, in addition to providing iron supplementation the complexes and compositions of the present invention provide certain advantages based on the presence of polydextrose (e.g., its low glycemic index and high fiber content).Type: ApplicationFiled: April 28, 2020Publication date: November 5, 2020Applicant: Particle Dynamics International, LLCInventors: Paul Brady, Keith Cromack
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Patent number: 10682375Abstract: The present invention generally relates to iron-polysaccharide (polydextrose) complexes and methods for the preparation thereof. In particular, the present invention relates to iron-polydextrose complexes and methods for the preparation thereof. The inventive complexes are suitable for use in various compositions, including particulate compositions that may be incorporated in various forms of administration, including tablets, capsules, and intravenous formulations. The complexes and compositions of the present invention are suitable for use in the treatment of iron deficient anemia. Advantageously, in addition to providing iron supplementation the complexes and compositions of the present invention provide certain advantages based on the presence of polydextrose (e.g., its low glycemic index and high fiber content).Type: GrantFiled: September 24, 2018Date of Patent: June 16, 2020Assignee: Particle Dynamics International, LLCInventors: Paul Brady, Keith Cromack
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Publication number: 20200170291Abstract: The present invention is generally directed to processes for producing lactitol granulates. The present invention is also directed to lactitol granulates exhibiting one or more desirable and improved properties as compared to prior lactitol granulates.Type: ApplicationFiled: May 22, 2018Publication date: June 4, 2020Applicant: PARTICLE DYNAMICS INTERNATIONAL, LLCInventors: Keith Cromack, Steve Freebersyser, Paul Brady
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Patent number: 10258647Abstract: The present invention generally relates to iron-polysaccharide (polydextrose) complexes and methods for the preparation thereof. In particular, the present invention relates to iron-polydextrose complexes and methods for the preparation thereof. The inventive complexes are suitable for use in various compositions, including particulate compositions that may be incorporated in various forms of administration, including tablets, capsules, and intravenous formulations. The complexes and compositions of the present invention are suitable for use in the treatment of iron deficient anemia. Advantageously, in addition to providing iron supplementation the complexes and compositions of the present invention provide certain advantages based on the presence of polydextrose (e.g., its low glycemic index and high fiber content).Type: GrantFiled: August 30, 2016Date of Patent: April 16, 2019Assignee: PARTICLE DYNAMICS INTERNATIONAL, LLCInventors: Paul Brady, Keith Cromack
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Publication number: 20190022138Abstract: The present invention generally relates to iron-polysaccharide (polydextrose) complexes and methods for the preparation thereof. In particular, the present invention relates to iron-polydextrose complexes and methods for the preparation thereof. The inventive complexes are suitable for use in various compositions, including particulate compositions that may be incorporated in various forms of administration, including tablets, capsules, and intravenous formulations. The complexes and compositions of the present invention are suitable for use in the treatment of iron deficient anemia. Advantageously, in addition to providing iron supplementation the complexes and compositions of the present invention provide certain advantages based on the presence of polydextrose (e.g., its low glycemic index and high fiber content).Type: ApplicationFiled: September 24, 2018Publication date: January 24, 2019Applicant: Particle Dynamics International, LLCInventors: Paul Brady, Keith Cromack
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Publication number: 20170216224Abstract: The present invention generally relates to improvements in the bioavailability and/or solubility of coenzyme Q10. For example, the present invention relates to methods for preparing particulate compositions including coenzyme Q10 that generally comprise dispersing and/or dissolving the coenzyme Q10 throughout a suitable solvent, and combining the coenzyme Q10 and an encapsulating (e.g., microencapsulating) agent. The present invention also generally relates to particulate compositions comprising coenzyme Q10 that exhibit improved bioavailability and/or solubility as compared to previous coenzyme Q10 products.Type: ApplicationFiled: April 20, 2017Publication date: August 3, 2017Applicant: PARTICLE DYNAMICS INTERNATIONAL, LLCInventor: Irwin C. Jacobs
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Patent number: 9655849Abstract: The present invention generally relates to improvements in the bioavailability and/or solubility of coenzyme Q10. For example, the present invention relates to methods for preparing particulate compositions including coenzyme Q10 that generally comprise dispersing and/or dissolving the coenzyme Q10 throughout a suitable solvent, and combining the coenzyme Q10 and an encapsulating (e.g., microencapsulating) agent. The present invention also generally relates to particulate compositions comprising coenzyme Q10 that exhibit improved bioavailability and/or solubility as compared to previous coenzyme Q10 products.Type: GrantFiled: March 16, 2012Date of Patent: May 23, 2017Assignee: Particle Dynamics International, LLCInventor: Irwin C. Jacobs
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Publication number: 20170056444Abstract: The present invention generally relates to iron-polysaccharide (polydextrose) complexes and methods for the preparation thereof. In particular, the present invention relates to iron-polydextrose complexes and methods for the preparation thereof. The inventive complexes are suitable for use in various compositions, including particulate compositions that may be incorporated in various forms of administration, including tablets, capsules, and intravenous formulations. The complexes and compositions of the present invention are suitable for use in the treatment of iron deficient anemia. Advantageously, in addition to providing iron supplementation the complexes and compositions of the present invention provide certain advantages based on the presence of polydextrose (e.g., its low glycemic index and high fiber content).Type: ApplicationFiled: August 30, 2016Publication date: March 2, 2017Applicant: Particle Dynamics International, LLCInventors: Paul Brady, Keith Cromack
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Publication number: 20160374942Abstract: The present invention generally relates to dosage forms for oral administration including one or more gelling agents. In particular, the present invention is directed to gelling agent-based dosage forms that are easily administered and taken, or swallowed. The present invention is also directed to gelling agent-based dosage forms that exhibit relatively low syneresis, are thermally stable, exhibit substantially constant active ingredient concentration, and/or exhibit one or more advantageous rheological properties. In particular, the present invention is directed to such gels containing one or more omega-3 fatty acids. The gelling agent-based dosage forms of the present invention are suitable for administration of a relatively large dose of active ingredient. The gelling agent-based dosage forms of the present invention are also suitable for administration of multiple active ingredients.Type: ApplicationFiled: August 16, 2016Publication date: December 29, 2016Applicant: PARTICLE DYNAMICS INTERNATIONAL, LLCInventors: Irwin Jacobs, Stephen Gee, Paul Brady
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Patent number: 9452135Abstract: The present invention generally relates to dosage forms for oral administration including one or more gelling agents. In particular, the present invention is directed to gelling agent-based dosage forms that are easily administered and taken, or swallowed. The present invention is also directed to gelling agent-based dosage forms that exhibit relatively low syneresis, are thermally stable, exhibit substantially constant active ingredient concentration, and/or exhibit one or more advantageous rheological properties. In particular, the present invention is directed to such gels containing one or more omega-3 fatty acids. The gelling agent-based dosage forms of the present invention are suitable for administration of a relatively large dose of active ingredient. The gelling agent-based dosage forms of the present invention are also suitable for administration of multiple active ingredients.Type: GrantFiled: March 19, 2013Date of Patent: September 27, 2016Assignee: Particle Dynamics International, LLCInventors: Irwin Jacobs, Stephen Gee, Paul Brady
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Patent number: 9339475Abstract: The present invention relates to spatially arranging a plurality of particles in a device for the oral delivery of a pharmaceutical. In particular, the plurality of particles is utilized for the oral delivery of a pharmaceutical to a subject via the drinking device.Type: GrantFiled: February 3, 2014Date of Patent: May 17, 2016Assignee: Particle Dynamics International, LLCInventors: Jonathan David Bortz, Yury Lagoviyer, Paul Timothy Brady
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Publication number: 20150140113Abstract: The present invention generally relates to dosage forms for oral administration including one or more gelling agents. In particular, the present invention is directed to gelling agent-based dosage forms that are easily administered and taken, or swallowed. The present invention is also directed to gelling agent-based dosage forms that exhibit relatively low syneresis, are thermally stable, exhibit substantially constant active ingredient concentration, and/or exhibit one or more advantageous rheological properties. In particular, the present invention is directed to such gels containing one or more omega-3 fatty acids. The gelling agent-based dosage forms of the present invention are suitable for administration of a relatively large dose of active ingredient. The gelling agent-based dosage forms of the present invention are also suitable for administration of multiple active ingredients.Type: ApplicationFiled: March 19, 2013Publication date: May 21, 2015Applicant: PARTICLE DYNAMICS INTERNATIONAL, LLCInventors: Irwin Jacobs, Stephen Gee, Paul Brady
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Patent number: 8859011Abstract: Compositions comprising calcium carbonate and processes for making such compositions are provided. The invention provides a granulation comprising about 95% to about 99% by weight calcium carbonate, about 0.5% to about 5% by weight of a binder and about 0.03% to about 3% by weight of a porosity increasing agent. A pharmaceutical or nutritional composition prepared from such a granulation comprises about 90% to about 99% by weight calcium carbonate, about 0.03% to about 3% by weight of a porosity increasing agent, and about 1% to about 10% by weight of other excipients. The composition provides a smaller tablet than conventional calcium carbonate compositions, for improved ease of swallowing.Type: GrantFiled: May 10, 2007Date of Patent: October 14, 2014Assignee: Particle Dynamics International, LLCInventors: Denis Stotler, Steven R. Freebersyser, R. Saul Levinson
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Publication number: 20140212505Abstract: The present invention relates to spatially arranging a plurality of particles in a device for the oral delivery of a pharmaceutical. In particular, the plurality of particles is utilized for the oral delivery of a pharmaceutical to a subject via the drinking device.Type: ApplicationFiled: February 3, 2014Publication date: July 31, 2014Applicant: Particle Dynamics International, LLCInventors: Jonathan David Bortz, Yury Lagoviyer, Paul Timothy Brady
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Patent number: 8679541Abstract: The present invention relates to spatially arranging a plurality of particles in a device for the oral delivery of a pharmaceutical. In particular, the plurality of particles is utilized for the oral delivery of a pharmaceutical to a subject via the drinking device.Type: GrantFiled: February 18, 2008Date of Patent: March 25, 2014Assignee: Particle Dynamics International, LLCInventors: Jonathan David Bortz, Yury Lagoviyer, Paul Timothy Brady
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Publication number: 20130330408Abstract: The present invention generally relates to improvements in the bioavailability and/or solubility of coenzyme Q10. For example, the present invention relates to methods for preparing particulate compositions including coenzyme Q10 that generally comprise dispersing and/or dissolving the coenzyme Q10 throughout a suitable solvent, and combining the coenzyme Q10 and an encapsulating (e.g., microencapsulating) agent. The present invention also generally relates to particulate compositions comprising coenzyme Q10 that exhibit improved bioavailability and/or solubility as compared to previous coenzyme Q10 products.Type: ApplicationFiled: March 16, 2012Publication date: December 12, 2013Applicant: PARTICLE DYNAMICS INTERNATIONAL, LLCInventor: Irwin C. Jacobs