Abstract: A drug delivery system is presented to increase the bioavailability of biopharmaceutic class II, III, or IV active agents.

Abstract: Disclosed herein are novel methods of treating diseases, novel dosage forms, and novel methods of modulating the pharmacokinetics of active ingredients.

Abstract: A system for packaging a plurality of tablets is disclosed that includes a container. The container comprises a generally elongated channel having a first end and a second end positioned below the first end. The first end has an aperture for receiving a plurality of tablets in series into the channel. The system also includes a container holding and vibration apparatus operable to hold the container and concurrently apply linear vibration in a direction to the container. A tablet delivery system is provided that is operable to deliver the tablets in series to the container in a direction that is substantially in alignment with the direction of linear vibration of the container. The linear vibration of the container provided is operable to align the tablets in a stacked formation within the channel of said container.

Abstract: An insert with an upwardly projecting protuberance proximate one end is inserted into an open container. The open container is conveyed continuously in a downstream direction with a container conveyor with the container opening upwardly. The insert is held above the conveyor at an insertion station by supporting a downstream portion of the insert: the protuberance bearing end of the insert being the upstream end of the insert. A pusher finger is driven downwardly against an upstream portion of the insert at a downstream side of the protuberance in order to push the upstream portion of the insert downwardly into the container. The upstream portion of the insert is pushed against an inside surface of the container with the pusher finger while the container is conveyed underneath the insert. Simultaneously, the support is removed from the downstream portion of the insert.

Abstract: The density of a spray plume generated by an aerosol delivery system (“ADS”) may be characterised by illuminating a face of the plume with light and then imaging the plume. The shape of the plume may be characterised by operating the ADS in a controlled manner to form a first spray plume. A face of the plume is illuminated and the plume imaged from a first side parallel to the spray axis of the plume. The ADS is then again operated in the controlled manner to form a second spray plume. A face of the second plume is illuminated and the second plume imaged from a second side which is parallel to the spray axis of the plume and perpendicular to the first side.

Abstract: The density of a spray plume generated by an aerosol delivery system (“ADS”) may be characterised by illuminating a face of the plume with light and then imaging the plume. The shape of the plume may be characterised by operating the ADS in a controlled manner to form a first spray plume. A face of the plume is illuminated and the plume imaged from a first side parallel to the spray axis of the plume. The ADS is then again operated in the controlled manner to form a second spray plume. A face of the second plume is illuminated and the second plume imaged from a second side which is parallel to the spray axis of the plume and perpendicular to the first side.