Patents Assigned to Peri Development Applications (1985) Ltd.
  • Human serum albumin expression construct
    Patent number: 5648243
    Abstract: The present invention provides DNA constructs comprising a promoter DNA sequence and a DNA sequence coding for human serum albumin. In one embodiment the human serum albumin sequence comprises at least one, but not all, of the introns in the naturally occurring gene encoding for the HSA protein. In another embodiment the DNA constructs comprise a 5' regulatory sequence which directs the expression and secretion of HSA protein in the milk of a transgenic animal. Preferably, the promoter gene is a milk protein promoter sequence such as .beta.-lactoglobulin. The present invention also provides transgenic animals which secrete HSA in the milk of lactating females. The present invention also provides vectors comprising the constructs of the present invention.
    Type: Grant
    Filed: September 21, 1994
    Date of Patent: July 15, 1997
    Assignees: Rhone-Poulenc Rorer Pharmaceuticals, Inc., Peri Development Applications (1985) Ltd.
    Inventors: David R. Hurwitz, Margret Nathan, Moshe Shani
  • Isolate of Trichoderma harzianum I-952 fungicidal compositions containing said isolate and use against B. cinerea and S. sclerotiorum
    Patent number: 5266316
    Abstract: The present invention relates to a novel biologically pure culture of Triderma Harzianum, I-952, to biological control compositions containing same and to methods of protecting flowering plants and fruits from the disease gray mold, caused by B. Cinerea and the disease white rot caused by S. Sclerotiorum with the compositions.
    Type: Grant
    Filed: March 26, 1993
    Date of Patent: November 30, 1993
    Assignees: Peri Development Applications (1985) Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Yigal Elad, Gilly Zimand, Ilan Chet