Abstract: An invasive, fluid velocity measuring wire guide particularly adapted and of a size (less than 0.030 inch) for subselective placement in the coronary arterial tree, which includes a Doppler mechanism for determining the blood flow velocity in the region of the distal end of the wire guide. Although the wire guide is particularly adapted for diagnosing coronary arterial disease subselectively; it is of such a size and manipulability to be useful in other blood flow and biological fluid flow analyses. Preferably, the wire guide is flexible and steerable for precise placement. The wire guide includes an elongated wire member having a Doppler crystal attached in longitudinal alignment at its distal end. Electrical leads extend from the Doppler crystal along the wire member to the appropriate test equipment for measuring the fluid flow velocity in the region of the Doppler crystal. Preferred embodiments of the Doppler means include piezoelectric crystals and piezoelectric polymers.

Abstract: A surgical instrument for installing a plurality of interlocking coupling members forming a compression anastomosis assembly, particularly suitable for use in achieving anastomosis of a resected tubular organ, with the instrument having a cutting portion designed and configured for rotational movement as the cutter advances to perform its intended functions of severing tissue and at least a portion of one of the members of the assembly. Also disclosed is a dual locking feature for alternately locking a driving component and an aligning component against movement where, in a first mode, the aligning component is operative when the driving component is locked and, in a second mode, the driving component is operative when the aligning component is locked. Additionally disclosed is a unique aligning component for aligning and exerting a compressive force on members of an associated coupling assembly.

Abstract: A bone cement is disclosed wherein the liquid component contains a therapeutic or diagnostic substance in combination with an emulsifying agent for said substance.

Abstract: A proximal femoral sealing device is disclosed for use in the application of bone cement under pressure to a surgically prepared medullary canal of a femur prior to the implantation of a hip prostesis. The proximal femoral sealing device is formed of a generally solid body member with a passageway and a flexible annular wall member extending from the body member. The sealing device has an anatomically shaped outer surface, corresponding to the exposed endosteal surface of a prepared medullary canal. A chamber defined by a flexible annular wall and the body member opens into the medullary canal. In turn, the passageway communicates with the chamber and permits insertion of a cement nozzle therethrough into the chamber. In operation, the proximal femoral sealing device is placed within the proximal end of a surgically prepared medullary canal.

Abstract: A pressure regulator including high and low pressure chambers separated by a divider having an opening, a closing member biassed to a closing position for closing the opening with a biassing force according to a desired pressure differential between the chambers, and a damping device for damping the resulting force on the closing member. There is also disclosed a fluid drainage system having a suction chamber with a suction regulator, and various arrangements of diaphragms for measuring pressure differentials. An anti-spill device for the draining system is disclosed as well.

Abstract: Devices and methods for transmitting neural signals from a proximal stump of a transected nerve to a prosthetic apparatus are disclosed employing microelectrodes, preferably conductive fiber networks, capable of sensing electrical signals from a nerve and transmitting such signals to a prosthetic apparatus; and a semipermeable guidance channel disposed about the microelectrodes. The channels include an opening adapted to receive the proximal stump of a transected nerve, such that the channel promotes the growth of the stump and the formation of an electrical connection between the transected nerve and the microelectrode.

Abstract: A femoral hip implant for use in patients requiring a long distal section of the femoral component is provided. For example, it can be used in patients undergoing revision surgery or requiring an implant with a long stem because of a fracture in the femur or a bone defect (for example as a result of a tumor removal). The implant is specially curved in its distal section so that the implant avoids impingement on the wall of the medullary canal even in the region of the isthumus of the bone.

Abstract: A high strength, low modulus, ductile, biocompatible titanium base alloy containing one or more isomorphous beta stabilizers, eutectoid beta stabilizers and optional alpha stabilizers, characterized by a modulus of elasticity not exceeding 100 GPa; a method for the preparation of said alloy and prostheses made from said alloy.

Abstract: A sensor for determining the partial pressure of carbon dioxide in a liquid, which comprises a carbon dioxide - permeable, liquid and ion-impermeable membrane enveloping an aqueous medium containing an absorber, a fluorescer and a source of bicarbonate ions, which medium exhibits variations in pH as a function of the partial pressure of dissolved carbon dioxide, the ratio of absorber to fluorescer and the characteristics of the absorption spectrum of the absorber and the excitation and emission spectra of the fluorescer being such that the partial pressure of carbon dioxide in the liquid may be determined from the pH of the aqueous medium as measured by the intensity of the fluorescent emission of the fluorescer.

Abstract: An improved metallic bone prosthesis having a porous coating for bone ingrowth or interlocking with bone cement is disclosed. The porous coating comprises two layers of generally ball-shaped metallic particles bonded together at their points of contact, e.g. by sintering, and defining between them a plurality of connected interstitial pores having an average pore size of from about 350 microns to about 500 microns. A high resistance to failure at the coating-substrate and bone-coating (or cement-coating) interfaces is achieved with the use of the improved prosthesis. Also disclosed are a novel method for affixing the porous coating to a metal substrate, and a knee joint prosthesis having bearing portions designed so that the function of said prosthesis closely approximates that of the natural knee.

Abstract: A novel prosthesis for use in repairing or replacing soft tissue is disclosed, which comprises a triaxially-braided fabric element having interwoven first, second and third sets of fibers, with the fibers of the second and third sets being oriented at substantially the same acute braiding angle with respect to the fibers of the first set. An elongated ligament prosthesis exhibiting the desired properties of high strength and high elasticity may be prepared by selecting high elasticity fibers for the first set, orienting said first set of fibers in the longitudinal direction of the prosthesis and selecting fibers having high yield strength and high Young's modulus for the second and third sets. A tubular prosthesis in which high elasticity fibers are oriented in the longitudinal direction is highly suitable for use as a vascular prosthesis. A prosthesis of the invention may also be manufactured in the form of a prosthetic heart valve leaflet.

Abstract: An adjustable housing suitable to be used with another housing and with a synthetic ligament so as to provide (for example) an anterior cruciate ligament prosthesis system for a knee joint is provided. The adjustable housing features an interior having a step shoulder located therein. A set screw in the housing fixes the synthetic ligament at a desired level of tension. The system has many significant advantages including (but not limited to) being able to withstand very high loads and being able to be retensioned repeatedly and easily without replacing the artificial ligament.

Abstract: A femoral spacer for positioning a femoral prosthesis is disclosed comprising a hollow body portion having an outside surface and an inside surface. The outside surface is adapted to contact the intramedullary canal wall, and the inside surface is adapted to contact the proximal portion of the prosthesis such that the prosthesis is substantially centered within the intramedullary canal.

Abstract: A three-component acetabular cup assembly for receiving and releasably retaining the femoral head component of a prosthesis, said cup assembly comprising an outer metal shell, a cup-shaped inner bearing of substantially rigid plastic fixedly secured within said metal shell, and a locking ring made from the same plastic as the inner bearing; the outer surface of the bearing and the inner surface of the locking ring having cooperating configurations forming a secure but releasable latch.

Abstract: An apparatus for draining fluids, for example, from a chest or pleural cavity, includes a collection chamber for collecting fluids through an inlet port for entry of the fluids. Also included is a dry or waterless suction control chamber in fluid communication with the collection chamber for regulating the degree of vacuum imposed in the collection chamber. If desired, a seal chamber can also be provided between the dry suction control chamber and the collection chamber so as to prevent any ambient or atmospheric air from passing into the collection chamber. The suction control chamber has a first inlet which is coupled to a suction source and a second inlet communicates with the ambient. A waterless regulator is provided for regulating the degree of suction imposed in the collection chamber at a plurality of predetermined preset levels of suction. This regulator is positioned between the suction inlet and the ambient inlet.

Abstract: A dressing delivery system comprising an adhesive-coated dressing, a release liner and a package are arranged such that the package acts as the means for applying the dressing to a skin area, with the opening of the package and the application of the dressing being accomplished in a single step. A simple method of preparing the dressing delivery system is also described.

Abstract: A method of producing a site for tissue ingrowth on a surgical implant by embedding a space occupier possessing a desired pattern in the surface of the implant at the desired location for ingrowth and then solubilizing the embedded space occupier to leave the pattern on the implant surface. Preferably, the implant is fabricated from a composite comprising a semi-crystalline thermoplastic resin such as polyetheretherketone or polyphenylene sulfide, and the space occupier is an acid-soluble metal plate machined to produce the desired pattern and removed by aqueous acid solution.

Abstract: A modular femoral internal implant system for use in the treatment of femoral disorders resulting from injury, disease or congenital defect includes at least three interconnectable components: (1) an elongated epiphyseal/metaphyseal implant, (2) an intramedullary rod and (3) an angled side plate having an elongated plate portion adapted to be secured to the outer cortical wall and a hollow sleeve adapted to extend into the femur. The epiphyseal/metaphyseal implant can be connected to either the angled side plate or the intramedullary rod. The system may also include an elongated bone plate connectable to the angled side plate, one or more additional epiphyseal/metaphyseal implants of variable length, an additional angled side plate, a distal buttress plate connectable to the elongated bone plate, and a plurality of bone screws of a universal design. Preferably, many or all of the components of the system are made of an inert, resilient titanium-base alloy.

Abstract: An invasive, fluid velocity measuring wire guide particularly adapted and of a size (less than 0.030 inch) for subselective placement in the coronary arterial tree, which includes a Doppler mechanism for determining the blood flow velocity in the region of the distal end of the wire guide. Although the wire guide is particularly adapted for diagnosing coronary arterial disease subselectively; it is of such a size and manipulability to be useful in other blood flow and biological fluid flow analyses. Preferably, the wire guide if flexible and steerable for precise placement. The wire guide includes an elongated wire member having a Doppler crystal attached in longitudinal alignment at its distal end. Electrical leads extend from the Doppler crystal along the wire member to the appropriate test equipment for measuring the fluid flow velocity in the region of the Doppler crystal.

Abstract: Apparatus for supporting a housing from a support including a bracket member formed of at least two opposed walls and having a post member extending between the walls, one of the walls capable of being positioned on the housing; and a hook member having one end rotatably secured about the post member for selective rotational movement from a first storage position to a second hanging position, the other end of the hook member being configured for engagement with the support, the one end of the hook member and the bracket being configured and dimensioned so that the hook member remains locked in the hanging position.