Abstract: A device is disclosed is disclosed for holding a membrane filter with use of a porous metal disk support for a membrane. The metal disk and membrane are sealed to a fusible enclosure by heat formed in the metal disk by induction heating. Such heat seals the metal disk and also seals the surface of the membrane to the fusible surrounding enclosure. The device is particularly useful in filtering particulate matter from intravenous solutions administered into the circulatory system of a human.
Abstract: Membranes which are useful in ultrafiltration processes are prepared by casting films from solutions of heteroaromatic polymers and subsequently quenching these films into solvents which cause gelation of the polymers. Examples of polymers employed in the preparation of microporous membranes are: poly-as-triazines, polyquinoxalines, poly (pyrazinoquinoxalines), polyquinolines and poly (anthrazolines). Membrane properties such as solvent flux, specific water content and pore size are readily controlled by proper choice of polymer concentration, solvents, and the addition of nonsolvents, salts and/or surfactants to the casting solutions.
Type:
Grant
Filed:
September 29, 1976
Date of Patent:
June 26, 1979
Assignee:
Pharmaco, Inc.
Inventors:
Wolfgang J. Wrasidlo, Soloman Spiegelman
Abstract: An elongated cylindrical body is provided and includes a diametrically reduced sharpened tubular needle extension on one end for opposing and piercing the puncturable seal of a medicament vial. The other end of the cylindrical body includes a slightly inwardly tapering diametrically enlarged counterbore communicated at its inner end with the interior of the tubular needle extension.
Abstract: A cap is provided for telescoping over the puncturable seal of a medicament vial and particularly a unit dose medicament vial. The cap includes a center outwardly projecting tubular extension including outer end circumferentially spaced inwardly projecting abutments. A needle structure including a generally cylindrical body is slidingly received within the tubular extension of the cap and includes a diametrically reduced sharpened tubular needle extension on its inner end opposing and for piercing the puncturable seal of the associated vial upon movement of the needle structure inwardly of the tubular extension or mounting portion of the cap.
Abstract: The safety cap of the present invention is for use with a medicament vial having a puncturable seal. The cap includes a cylindrical extension provided with a shape-retentive but slightly expandable cylindrical body slidable therein having a diametrically reduced sharpened tubular needle extension on its inner end for piercing the seal. The body includes first and second portions of slightly different diameters, with the portion of smaller diameter outermost, and an inwardly tapering center portion, thus defining two shoulders for cooperating with an inwardly projecting lip on the outer end of the cylindrical extension to resiliently resist inward movement of the body and to prevent outward withdrawal of the body after it has been pressed inwardly to puncture the seal.