Abstract: A multi-dose spray applicator is disclosed for dispensing a pharmaceutical liquid from a sealed container, said applicator comprising means for holding the container, a manually operable metering pump for delivering said pharmaceutical as a nasal spray, and a hollow needle associated with said pump for penetrating a membrane sealing said container and dispensing the pharmaceutical liquid through the pump, said container having a movable wall or plug which is movable to displace the liquid from the container as it is dispensed by the pump.