Patents Assigned to Pharmos Bioscience A/S
  • Screening compounds for activity in modulating chloride ion transport
    Patent number: 7851165
    Abstract: A method for screening a test compound for activity in modulating the activity of the chloride channel ClC-7 either directly or by modulating the subcellular localization of Ostm1 comprises determining whether test compound inhibits the binding of Ostm1 to ClC-7. Compounds active in the screen are candidates for use in treating bone resorption conditions such as Osteoporosis by modulating the activity of osteoclasts.
    Type: Grant
    Filed: December 18, 2006
    Date of Patent: December 14, 2010
    Assignee: Pharmos Bioscience A/S
    Inventors: Philipp Lange, Jens C. Fuhrmann, Thomas Jentsch
  • Screening Compounds for Activity in Modulating Chloride Ion Transport
    Publication number: 20090170127
    Abstract: A method for screening a test compound for activity in modulating the activity of the chloride channel ClC-7 either directly or by modulating the subcellular localization of Ostm1 comprises determining whether test compound inhibits the binding of Ostm1 to ClC-7. Compounds active in the screen are candidates for use in treating bone resorption conditions such as Osteoporosis by modulating the activity of osteoclasts.
    Type: Application
    Filed: December 18, 2006
    Publication date: July 2, 2009
    Applicant: PHARMOS BIOSCIENCE A/S
    Inventors: Philipp Lange, Jens C. Fuhrmann, Thomas Jentsch