Patents Assigned to Pharyx, Inc.
  • Methods and apparatus for independent control of product and reactant concentrations
    Patent number: 9574167
    Abstract: A microreactor with a reaction chamber comprising two sub-chambers with reconfigurable volumes, an input conduit with input valve, an un-filtered output conduit with first output valve, and a filtered output conduit with a second output valve is used to perform a method to control a different dilution rate for cells and molecules in continuous culture bioprocesses. In preferred embodiments flow control is achieved using the difference in volume of the two sub-chambers.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: February 21, 2017
    Assignee: Pharyx, Inc.
    Inventors: Harry Lee, Kevin Shao-Kwan Lee
  • Apparatus and methods to operate a microreactor
    Patent number: 9328962
    Abstract: The present invention provides apparatus and methods to operate microreactor devices through the controlled delivery of pressurized fluids. A heated reservoir, a heated manifold, and a heater for the microreactor device provides for the delivery of a pressurized gas while minimizing evaporation and condensation; and a fluid interface and pressure interlock provides for the delivery of aseptic fluids while minimizing contamination and fluid loss.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: May 3, 2016
    Assignee: Pharyx, Inc.
    Inventors: Harry Lee, Kevin Shao-Kwan Lee
  • Apparatus and methods to measure optical density
    Patent number: 9176060
    Abstract: The present invention provides apparatus and methods for measuring the optical density of a fluid by measuring the light transmission through a reconfigurable optical path. The optical path is reconfigured by the deflection of an elastic membrane wherein the optical path length through the fluid is determined by the position of the membrane relative to a fixed surface. The optical density can be determined from two measurements with different optical path lengths through the fluid.
    Type: Grant
    Filed: April 9, 2012
    Date of Patent: November 3, 2015
    Assignee: Pharyx, Inc.
    Inventors: Harry Lee, Kevin Shao-Kwan Lee
  • Methods and apparatus for independent control of product and reactant concentrations
    Publication number: 20140234954
    Abstract: A microreactor with a reaction chamber comprising two sub-chambers with reconfigurable volumes, an input conduit with input valve, an un-filtered output conduit with first output valve, and a filtered output conduit with a second output valve is used to perform a method to control a different dilution rate for cells and molecules in continuous culture bioprocesses. In preferred embodiments flow control is achieved using the difference in volume of the two sub-chambers.
    Type: Application
    Filed: February 14, 2014
    Publication date: August 21, 2014
    Applicant: Pharyx, Inc
    Inventors: Harry Lee, Kevin Shao-Kwan Lee
  • Apparatus and methods to operate a microreactor
    Publication number: 20130196276
    Abstract: The present invention provides apparatus and methods to operate microreactor devices through the controlled delivery of pressurized fluids. A heated reservoir, a heated manifold, and a heater for the microreactor device provides for the delivery of a pressurized gas while minimizing evaporation and condensation; and a fluid interface and pressure interlock provides for the delivery of aseptic fluids while minimizing contamination and fluid loss.
    Type: Application
    Filed: January 25, 2013
    Publication date: August 1, 2013
    Applicant: Pharyx, Inc.
    Inventor: Pharyx, Inc.