Patents Assigned to Phytronix Technologies, Inc.
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Publication number: 20230093230Abstract: Laser diode thermal desorption coupled with tandem mass spectrometry systems and methods are described to detect at least one target analyte in a sample by negative ion mode mass spectrometry. For instance, the system and method involve desorbing a sample prepared for mass spectrometry analysis by laser diode thermal desorption to obtain a desorbed sample, and then ionizing the desorbed sample under conditions to generate an ionized analyte flow comprising a superoxide radical anion (O2.?) adduct detectable by negative ion mode mass spectrometry; and then detecting the O2.? adduct by negative ion mode mass spectrometry, to thereby detect the target analyte.Type: ApplicationFiled: January 29, 2021Publication date: March 23, 2023Applicant: PHYTRONIX TECHNOLOGIES INC.Inventors: Pierre PICARD, Serge AUGER
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Patent number: 11049711Abstract: A mass spectrometer having a triple ionization interface for ionizing sample components is provided. The ionization interface of the mass spectrometer includes a means for ionizing sample components via electrostatic ionization, atmospheric pressure chemical ionization, and laser diode thermal desorption.Type: GrantFiled: June 4, 2018Date of Patent: June 29, 2021Assignees: SHIMADZU CORPORATION, PHYTRONIX TECHNOLOGIES INC.Inventors: Tairo Ogura, Jean Lacoursiere, Pierre Picard
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Publication number: 20210151311Abstract: A mass spectrometer having a triple ionization interface for ionizing sample components is provided. The ionization interface of the mass spectrometer includes a means for ionizing sample components via electrostatic ionization, atmospheric pressure chemical ionization, and laser diode thermal desorption.Type: ApplicationFiled: June 4, 2018Publication date: May 20, 2021Applicants: SHIMADZU CORPORATION, PHYTRONIX TECHNOLOGIES INC.Inventors: Tairo OGURA, Jean LACOURSIERE, Pierre PICARD
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Publication number: 20180292375Abstract: A method for detecting boar taint in a fat sample is provided. The method includes extracting boar taint compounds from the fat sample to obtain a boar taint extract which includes indole components and androstenone. The method also includes derivatizing the indole components such that the derivatized indole components have a lower volatility than the indole components. The method also includes desorbing the derivatized indole components and the androstenone by Laser Diode Thermal Desorption (LDTD), and ionizing the desorbed analytes. The content of boar taint compounds in the fat sample can then be determined by subjecting the ionized analytes to mass spectrometry.Type: ApplicationFiled: March 2, 2017Publication date: October 11, 2018Applicant: PHYTRONIX TECHNOLOGIES INC.Inventors: Pierre PICARD, Serge AUGER
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Patent number: 9209003Abstract: Methods and systems for quantifying analytes in a biological sample are provided comprising preparing a biological sample for mass spectrometric analysis, utilizing an ionization source to ionize at least a portion of the prepared biological sample to generate an ionized analyte flow, introducing the ionized analyte flow into a differential mobility spectrometer set at a compensation voltage selected to extract ionized analyte molecules from the ionized analyte flow, introducing an output analyte flow of the differential mobility spectrometer into a mass spectrometer to detect and quantify analyte ions in the output analyte flow.Type: GrantFiled: October 26, 2012Date of Patent: December 8, 2015Assignees: DH TECHNOLOGIES DEVELOPMENT PTE. LTD., PHYTRONIX TECHNOLOGIES INC.Inventors: Serge Auger, Gregory Blachon, Hesham Ghobarah, Michael Jarvis, Pierre Picard
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Patent number: 7582863Abstract: An apparatus and method for regenerating ion samples for a mass spectrometer are provided. Source samples are loaded on a support which is heated by a laser beam, desorbing the sample without ionization. The desorbed sample is carried by a carrier gas flow through a transfer tube, at the output of which it is ionized by corona discharge or photo-ionization. The obtained ionized sample may be analyzed in a mass spectrometer or used to serve any other appropriate purpose.Type: GrantFiled: November 28, 2007Date of Patent: September 1, 2009Assignee: Phytronix Technologies, Inc.Inventors: Pierre Picard, Andre L'heureux, Jean Lacoursiere, Philippe Nobert, Sylvain Letarte, Alexandre Vallieres, Réal Paquin, Denis Lessard
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Publication number: 20080067357Abstract: An apparatus and method for regenerating ion samples for a mass spectrometer are provided. Source samples are loaded on a support which is heated by a laser beam, desorbing the sample without ionization. The desorbed sample is carried by a carrier gas flow through a transfer tube, at the output of which it is ionized by corona discharge or photo-ionization. The obtained ionized sample may be analyzed in a mass spectrometer or used to serve any other appropriate purpose.Type: ApplicationFiled: November 28, 2007Publication date: March 20, 2008Applicant: Phytronix Technologies, Inc.Inventors: Pierre Picard, Andre L'heureux, Jean Lacoursiere, Philippe Nobert, Sylvain Letarte, Alexandre Vallieres, Robert Tiveron, Real Paquin, Denis Lessard
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Patent number: 7321116Abstract: An apparatus and method for regenerating ion samples for a mass spectrometer are provided. Source samples are loaded on a support which is heated by a laser beam, desorbing the sample without ionization. The desorbed sample is carried by a carrier gas flow through a transfer tube, at the output of which it is ionized by corona discharge or photo-ionization. The obtained ionized sample may be analyzed in a mass spectrometer or used to serve any other appropriate purpose.Type: GrantFiled: May 20, 2005Date of Patent: January 22, 2008Assignee: Phytronix Technologies, Inc.Inventors: Pierre Picard, Denis Lessard, André L'Heureux, Jean Lacoursiere, Philippe Nobert, Sylvain Letarte, Alexandre Vallieres, Robert Tiveron, Réal Paquin
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Publication number: 20060054807Abstract: An apparatus and method for regenerating ion samples for a mass spectrometer are provided. Source samples are loaded on a support which is heated by a laser beam, desorbing the sample without ionization. The desorbed sample is carried by a carrier gas flow through a transfer tube, at the output of which it is ionized by corona discharge or photo-ionization. The obtained ionized sample may be analyzed in a mass spectrometer or used to serve any other appropriate purpose.Type: ApplicationFiled: May 20, 2005Publication date: March 16, 2006Applicant: PHYTRONIX TECHNOLOGIES, INC.Inventors: Pierre Picard, Denis Lessard, Andre L'Heureux, Jean Lacoursiere, Philippe Nobert, Sylvain Letarte, Alexandre Vallieres, Robert Tiveron, Real Paquin