Abstract: The present invention relates to a Silybum marianum (L.) Gaertn. extract comprising less than 0.2% by weight of silymarin with respect to the weight of the dry extract, as well as pharmaceutical and cosmetic compositions containing same, the preparation method thereof and uses thereof as a medicinal product, particularly in the treatment of acne, seborrhoea, seborrheic dermatitis and/or rosacea.
Type:
Application
Filed:
June 30, 2017
Publication date:
June 13, 2019
Applicant:
PIERRE FABRE DERMO-COSMETIQUE
Inventors:
Jean-Hilaire SAURAT, Olivier SORG, Mathieu LETI, Bernard FABRE
Abstract: The invention relates to a method for producing an extract of a matrix of vegetable origin, particularly a plant, involving a solid-liquid extraction by means of an aqueous solution containing at least one, preferably agro-sourced, non-ionic amphiphilic compound, at a concentration at least equal to the minimum hydrotrope concentration thereof.
Abstract: The present invention relates to a method for producing a crude extract enriched in pentacyclic triterpenes, including celastrol, from cells of a plant from the Celastraceae family; an enriched crude extract that can be obtained using such a method; therapeutic applications of such an extract; and pharmaceutical and dermocosmetic compositions containing such an extract.
Type:
Application
Filed:
May 12, 2017
Publication date:
May 9, 2019
Applicant:
PIERRE FABRE DERMO-COSMETIQUE
Inventors:
Thien NGUYEN, Adrien COUSY, Nicolas STEWARD
Abstract: The present invention relates to a preparation obtained from an in vitro culture of undifferentiated cells of Mimosa pudica, as well as to the preparation method thereof; a cosmetic or dermatological composition comprising said preparation; and the uses thereof for the treatment of inflammatory skin conditions, as an antioxidant agent in the treatment of oxidative stress caused by environmental pollution, and as an anti-aging agent.
Abstract: The invention concerns topical compositions based on retinaldehyde, glycylglycine oleamide and, if necessary, delta-tocopheryl-glucopyranoside, and their use in cosmetology and dermatology to combat skin ageing and more particularly light-induced skin ageing.
Type:
Grant
Filed:
June 3, 2014
Date of Patent:
February 26, 2019
Assignee:
PIERRE FABRE DERMO-COSMETIQUE
Inventors:
Daniel Bacqueville, Patrick Bogdanowicz, Jean-Hilaire Saurat, Olivier Sorg
Abstract: The present invention concerns a combination of a retinoid and a diol and polyunsaturated fatty acid ester, a dermatological or dermocosmetic composition containing such a combination and use of same in the treatment of acne and the prevention of retentional lesions. The present invention also concerns a retinoid, optionally in combination with a diol and polyunsaturated fatty acid ester, for use in the prevention of retentional lesions.
Type:
Grant
Filed:
February 29, 2016
Date of Patent:
January 29, 2019
Assignee:
PIERRE FABRE DERMO-COSMETIQUE
Inventors:
Nathalie Castex-Rizzi, Daniel Redoules, Sandrine Bessou-Touya, Jean-Hilaire Saurat
Abstract: This invention relates to a topical, cosmetic or dermatological composition, comprising a 1,3 diglyceride having the general formula (I), in which the radicals R1 and R2 represent, independently of one another, a C13 to C40 saturated and linear alkyl radical, and at least one cosmetic or dermatological excipient for a topical application on the skin. This invention also relates to such a composition, or a 1,3 diglyceride having the formula (I), for its use in protecting the skin, in countering the weakening of the skin barrier and in preventing or reducing the penetration of exogenous molecules into the skin following a weakening of the skin barrier.
Abstract: The invention concerns the use of a cosmetic compound to improve hair strength, said cosmetic compound comprising as an active ingredient an extract of Balanites almonds.
Abstract: The invention relates to the use of L-serine as a drug for preventing and/or treating an inflammatory response of the skin caused by the overexpression and/or the overactivation of PAR2 receptors.
Abstract: A massager device includes a structure having a contact face and a handling face. A pair of notched rollers is on the contact face of the structure. The notched rollers freely rotates around intersecting axes. The notched rollers are attached to the structure by elastic suspensions. A gripping shape is on the handling face of the structure, opposite to the contact face. The gripping shape forms a cap wrapping the surface of the structure.
Type:
Grant
Filed:
May 6, 2016
Date of Patent:
June 26, 2018
Assignee:
PIERRE FABRE DERMO-COSMETIQUE
Inventors:
Olivier Jean Marty, Marie Chenal, Bénédicte Roucayrol
Abstract: The present invention relates to a combination comprising a hyaluronic acid or a salt thereof and a sulphated polysaccharide of which the molecular weight is between 5 and 25 kDa, which is of use in particular for combating the signs of skin ageing or for treating and healing skin wounds.
Type:
Grant
Filed:
April 30, 2015
Date of Patent:
June 12, 2018
Assignee:
PIERRE FABRE DERMO-COSMETIQUE
Inventors:
Stéphane Poigny, Hélène Hernandez-Pigeon, Jean-Hilaire Saurat, Gürkan Kaya
Abstract: An association comprising a peptide is described containing the sequence A-Lys-Gly-His-Lys-NH2 (SEQ ID NO: 1), wherein A is the radical corresponding to a C1 to C18 saturated or unsaturated fatty acid, and glyceryl laurate or one of the derivatives thereof. The use thereof for stimulating hair growth is also described.
Abstract: The present invention relates to a process for obtaining a juice of fresh plants, characterized in that said fresh plants, with the exclusion of the seeds only, are subjected to a thermomechanical treatment consisting in extruding the fresh plants in an extruder, combined with a heat treatment which makes it possible to inactivate the endogenous enzymes and to preserve the molecules of compounds of interest in the native form thereof, in the absence of solvent, followed by a juice recovery operation.
Type:
Grant
Filed:
September 18, 2014
Date of Patent:
March 13, 2018
Assignees:
PIERRE FABRE DERMO-COSMETIQUE, PIERRE FABRE MEDICAMENT
Abstract: The invention relates to a method for producing an extract of a matrix of vegetable origin, particularly a plant, characterised in that the matrix of vegetable origin undergoes a mechanical treatment consisting in extruding the matrix of vegetable origin in an extruder, in association or not with a heat treatment, in the presence of an aqueous solution containing at least one hydrotrope agent, particularly at a concentration at least equal to the minimum hydrotrope concentration thereof, followed by an operation of recovering the extract.
Abstract: The present invention concerns a combination of a retinoid and a diol and polyunsaturated fatty acid ester, a dermatological or dermocosmetic composition containing such a combination and use of same in the treatment of acne and the prevention of retentional lesions. The present invention also concerns a retinoid, optionally in combination with a diol and polyunsaturated fatty acid ester, for use in the prevention of retentional lesions.
Type:
Application
Filed:
February 29, 2016
Publication date:
February 8, 2018
Applicant:
PIERRE FABRE DERMO-COSMETIQUE
Inventors:
Nathalie CASTEX-RIZZI, Daniel REDOULES, Sandrine BESSOU-TOUYA, Jean-Hilaire SAURAT
Abstract: The invention relates to zinc coceth sulfate for the use thereof as an antibacterial agent for treating skin disorders associated with Propionibacterium acnes.
Abstract: The invention relates to a method for producing an extract of a matrix of vegetable origin, particularly a plant, involving a solid-liquid extraction by means of an aqueous solution containing at least one, preferably agro-sourced, non-ionic amphiphilic compound, at a concentration at least equal to the minimum hydrotrope concentration thereof.
Abstract: The present invention concerns a combination comprising the dipeptide L-alanyl-L-glutamine, hyaluronic acid or one of the salts of same and an oat extract, advantageously intended for healing wounds and repairing skin lesions.
Abstract: The present invention concerns a topical, cosmetic or pharmaceutical preparation containing a combination of 3 or 4 solar filters comprising: one or two UVA filters to obtain a critical wavelength >370 nm, chosen from among: i. 5,6,5,6-tetraphenyl-3,3?-(1,4-phenylene)-bis[1,2,4]triazine, ii. 1,1?-(1,4-piperazinediyl)bis[1-[2-[4-(diethylamino)-2-hydroxybenzoyl]phenyl]-methanone iii. Butyl Methoxydibenzoylmethane (BMDBM), in a quantity less than 2% by weight with regard to the total weight of said composition, iv. Hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate, 2,4-Bis[4-(2-ethylhexyloxy)-2-hydroxyphenyl]-6-(4-methoxyphenyl)-1,3,5-triazine=(BEMT), one or two filters chosen from among UVB filters, except octocrylene, PABA and ethylhexyl methoxycinnamate, said composition also containing a pharmaceutically or cosmetically acceptable excipient.